Colon News and Research

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Study finds anti-gout medication may reduce risk of colorectal cancer

Allopurinol, a relatively inexpensive anti-gout medication that has been on the market for more than 20 years, may have some activity against colorectal adenomas, according to data presented at the Ninth Annual AACR Frontiers in Cancer Prevention Research Conference, held here Nov. 7-10, 2010.

8 Nov 2010

Blocking beta glucuronidase enzyme could eliminate side effects of CPT-11 in colon cancer treatment

A debilitating side effect of a widely used but harshly potent treatment for colon cancer could be eliminated if a promising new laboratory discovery bears fruit.

8 Nov 2010

Laparoscopic surgery safe and effective for removing bowel tumours

Laparoscopic or 'keyhole' surgery is a safe, effective way of removing bowel tumours and should be offered to all patients undergoing surgery for colorectal cancer, according to researchers from the University of Leeds.

8 Nov 2010

Onconome receives $231,000 cash grant under QTDP program

Onconome, Inc. announced today that it was awarded a cash grant totaling approximately $231,000 under the U.S. Government's Qualifying Therapeutic Discovery Project (QTDP) program. The QTDP was enacted as part of the Patient Protection and Affordable Care Act of 2010.

7 Nov 2010

EDP Biotech receives $244,000 grant under QTDP program for colon cancer blood test

EDP Biotech Corporation was awarded a $244,000 grant from the federal government under the Qualifying Therapeutic Discovery Project program as a result of the company's work in the development of their ColoMarker test, an early detection blood test for colon cancer.

4 Nov 2010

Mouse study indicates black raspberries can prevent colorectal cancer

Black raspberries are highly effective in preventing colorectal tumors in two mouse models of the disease, according to a University of Illinois at Chicago study. The findings are published in the November issue of Cancer Prevention Research.

3 Nov 2010

NSAIDs drugs prevent colon cancer: Research

Nonsteroidal anti-inflammatory drugs (NSAIDs) prevent colon cancer by triggering diseased stem cells to self-destruct, according to researchers at the University of Pittsburgh Cancer Institute (UPCI) and the University of Pittsburgh School of Medicine.

2 Nov 2010

H. pylori infection reduces severity of Salmonella-induced colitis: Research

Helicobacter pylori, a common stomach bacterium, reduced the severity of inflammation of the colon caused by Salmonella in mice, according to research from U-M Medical School scientists.

2 Nov 2010

Mechanism that controls embryonic development could also prevent cancer

Researchers from Mount Sinai School of Medicine have identified a mechanism controlling the function of a protein that binds to DNA during embryonic development and may function to prevent abnormal tumor growth.

29 Oct 2010

Novel small molecule inhibitors may provide new therapy for colon cancer

Researchers are one step closer to providing a new therapy for colon cancer, after findings revealed that a small molecule focal adhesion kinase (FAK) inhibitor known as Y15 effectively blocked cell viability, promoted detachment and apoptosis, and decreased tumor growth in mice. These findings were presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

Researchers identify small-molecule inhibitors that effectively target FAK enzyme in colon cancer

Researchers have identified two small-molecule inhibitors that effectively targeted the focal adhesion kinase (FAK), an enzyme present in certain cancers that helps tumors thrive and survive.

29 Oct 2010

Researchers develop three-dimensional culture that mimics growth patterns of colon cancer stem cells

University of Pittsburgh researchers have devised a three-dimensional system in laboratory culture that mimics the growth patterns of colon cancer stem cells in patients. Their findings were presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held Oct. 27-30, 2010.

29 Oct 2010

New noninvasive stool DNA test to predict colorectal cancer

An investigational DNA methylation test could alter the screening landscape for colorectal cancer, according to data presented at the American Association for Cancer Research special conference on Colorectal Cancer: Biology to Therapy, held here Oct. 27-30, 2010.

29 Oct 2010

Researchers find link between telomere length and colorectal cancer risk

For the first time, researchers have found a link between long telomeres and an increased risk for colorectal cancer, according to research presented at the American Association for Cancer Research special conference on Colorectal Cancer Biology to Therapy, held here Oct. 27-30, 2010.

29 Oct 2010

IsoRay completes Cs-131 brachytherapy seeds feasibility study for breast cancer treatment

IsoRay, Inc. announced, today, it has completed an initial feasibility study, which demonstrates the ability to use its patented Cesium-131 (Cs-131) brachytherapy seeds (internal radiation therapy) in accelerated partial breast irradiation (APBI) for breast cancer treatment.

28 Oct 2010

Pancreatic cancer develops and spreads more slowly than thought before

Pancreatic cancer develops and spreads much more slowly than scientists have thought, according to new research from Johns Hopkins investigators. The finding indicates that there is a potentially broad window for diagnosis and prevention of the disease.

28 Oct 2010

Government institutions need to find alternate funding sources for colorectal cancer screening

Offering colorectal cancer screening to poor minority women during mammography visits can effectively expand screening in this otherwise underserved population, although lack of medical insurance remains a significant barrier. That is the conclusion of a new study published early online in Cancer, a peer-reviewed journal of the American Cancer Society. The results highlight the need to find alternative funding sources for colorectal cancer screening from the government or private institutions.

28 Oct 2010

Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Laureate Pharma, Inc., a full-service contract development and manufacturing organization, announced today that they have entered into a development and manufacturing agreement to produce AV-203, AVEO Pharmaceutical's (Cambridge, MA) novel monoclonal antibody targeted against ErbB3.

28 Oct 2010

Researchers identify signaling pathway that promotes metastasis of pediatric bone cancer

Researchers have identified an important signaling pathway that, when blocked, significantly decreases the spread of pediatric bone cancer. Their research showed that the Notch pathway and Hes1 gene play a key role in promoting the metastasis of osteosarcoma, the most common form of bone cancer in children.

26 Oct 2010

Experts identify efficient way to increase minority access to colorectal cancer screening

Minority patients have a significantly decreased survival from colon cancer compared to white patients, most often as a result of a late diagnosis. To help address this problem, a team of healthcare professionals at Memorial Sloan-Kettering Cancer Center has identified an efficient way to increase minority access to lifesaving colorectal cancer screening (CRCS) in communities where multiple barriers to preventive care exist.

25 Oct 2010

Colon News and Research

Study finds anti-gout medication may reduce risk of colorectal cancer

Blocking beta glucuronidase enzyme could eliminate side effects of CPT-11 in colon cancer treatment

Laparoscopic surgery safe and effective for removing bowel tumours

Onconome receives $231,000 cash grant under QTDP program

EDP Biotech receives $244,000 grant under QTDP program for colon cancer blood test

Mouse study indicates black raspberries can prevent colorectal cancer

NSAIDs drugs prevent colon cancer: Research

H. pylori infection reduces severity of Salmonella-induced colitis: Research

Mechanism that controls embryonic development could also prevent cancer

Novel small molecule inhibitors may provide new therapy for colon cancer

Researchers identify small-molecule inhibitors that effectively target FAK enzyme in colon cancer

Researchers develop three-dimensional culture that mimics growth patterns of colon cancer stem cells

New noninvasive stool DNA test to predict colorectal cancer

Researchers find link between telomere length and colorectal cancer risk

IsoRay completes Cs-131 brachytherapy seeds feasibility study for breast cancer treatment

Pancreatic cancer develops and spreads more slowly than thought before

Government institutions need to find alternate funding sources for colorectal cancer screening

Laureate enters agreement with AVEO to produce AV-203 monoclonal antibody against ErbB3

Researchers identify signaling pathway that promotes metastasis of pediatric bone cancer

Experts identify efficient way to increase minority access to colorectal cancer screening

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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