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SynCardia Systems raises $14M to fund the rapid growth of Total Artificial Heart

Privately held SynCardia Systems, Inc. announced today that it had raised $14 million to fund the rapid growth of the only approved medical device that eliminates the symptoms and source of end-stage heart failure, the SynCardia temporary Total Artificial Heart. The SynCardia Total Artificial Heart is the world's first and only FDA, Health Canada and CE (Europe) approved Total Artificial Heart.

17 Dec 2013

BWH receives $140M grant from NIAID to support ongoing research led by AIDS Clinical Trial Group

The National Institute of Allergy and Infectious Diseases has awarded two seven-year grants to Brigham and Women's Hospital to fund the AIDS Clinical Trial Group Network.

16 Dec 2013

Women are more susceptible to damaging effects of alcohol than men

Women are more susceptible to the damaging effects of alcohol than men because they are generally smaller in stature and have less body water than men, according to a leading Houston hepatologist.

16 Dec 2013

Research roundup: Long-term care use varies dramatically by state; health spending slowdown explained

In 2012, about 58,500 paid, regulated long-term care services providers served about 8 million people in the United States. Long-term care services were provided by 4,800 adult day services centers, 12,200 home health agencies, 3,700 hospices, 15,700 nursing homes, and 22,200 assisted living and similar residential care communities. Each day in 2012, there were 273,200 participants enrolled in adult day services centers, 1,383,700 residents in nursing homes, and 713,300 residents in residential care communities; in 2011, about 4,742,500 patients received services from home health agencies, and 1,244,500 patients received services from hospices. Provider sectors differed in ownership, and average size and supply varied by region (Harris-Kojetin et al., 12/12).

16 Dec 2013

Groundbreaking UVA research receives $3.3M NIH grant to increase lungs for transplantation

Groundbreaking research at the University of Virginia School of Medicine that aims to dramatically increase the number of lungs that can be used for transplant has received a $3.3 million grant from the National Institutes of Health.

13 Dec 2013

New reports demonstrate the effectiveness of modified T cells in treating blood-borne cancers

At the 2013 American Society of Hematology meeting in Dec. 2013, James Kochenderfer, M.D., investigator in the Experimental Transplantation and Immunology Branch, NCI, presented findings from two clinical trials evaluating the use of genetically modified immune system T cells as cancer therapy.

12 Dec 2013

Findings help inform ongoing discussions regarding potential changes to US' lung allocation policy

A new analysis has found no evidence that children aged 6 to 11 years seeking a deceased donor lung transplant are disadvantaged in the current US lung allocation system. The findings, which are published in the American Journal of Transplantation, help inform ongoing discussions regarding potential changes to the nation's lung allocation policy.

12 Dec 2013

New guidelines to manage heart failure in children

Heart failure in children is an important cause of childhood health problems and death. The Children's Heart Failure Study Group of the Canadian Cardiovascular Society, in collaboration with the Canadian Pediatric Cardiology Association, has developed new guidelines to assist practitioners in primary care and emergency departments to recognize and successfully manage heart failure in children with undiagnosed heart disease and symptoms of possible heart failure.

12 Dec 2013

Emergent BioSolutions enters into definitive agreement to acquire Cangene

Emergent BioSolutions Inc.announced that it has entered into a definitive agreement with Cangene Corporation (TSX: CNJ) under which Emergent will acquire all of the outstanding common shares of Cangene in an all-cash transaction valued at $3.24 per share on a fully diluted basis for an aggregate purchase price of $222 million.

12 Dec 2013

New guidelines developed to manage heart failure in children with undiagnosed heart disease

12 Dec 2013

Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

A team of researchers from Brigham and Women's Hospital, Boston Medical Center and Massachusetts General Hospital has been awarded $25 million by the National Institutes of Health to conduct a four-year, randomized clinical trial-the BEST-CLI Trial (Best Endovascular versus Best Surgical Therapy in Patients with Critical Limb Ischemia). The trial will compare traditional bypass surgery with the less invasive alternative of endovascular treatment for patients with critical limb ischemia.

11 Dec 2013

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

Johns Hopkins researchers have identified a new way to predict which heart failure patients are likely to see their condition get worse and which ones have a better prognosis. Their study is one of the first to show that energy metabolism within the heart, measured using a noninvasive magnetic resonance imaging test, is a significant predictor of clinical outcomes, independent of a patient's symptoms or the strength of the heart's ability to pump blood, known as the ejection fraction.

11 Dec 2013

SynCardia Systems sets new record with 150th implant of temporary Total Artificial Heart

SynCardia Systems, Inc. continues to set records with the implantation of the year's 150th SynCardia temporary Total Artificial Heart on Nov. 26, 2013.

11 Dec 2013

Study shows children with ALL can safely receive intravenous infusions of chemotherapy

Children with acute lymphoblastic leukemia (ALL), the most common form of pediatric cancer, can safely receive intravenous infusions of a reformulated mainstay of chemotherapy that has been delivered via painful intramuscular injection for more than 40 years, research suggests.

11 Dec 2013

Celgene: FIRST trial meets primary endpoint in patients newly diagnosed with multiple myeloma

Celgene today announced that data from the FIRST (Frontline Investigation of lenalidomide and dexamethasone vs. standard thalidomide) trial was presented on Sunday 8 December, during the Plenary Scientific Session at the 55th American Society Hematology annual meeting in New Orleans. FIRST (MM-020/IFM 07-01) a phase III, multi-centre study in patients newly diagnosed with multiple myeloma and ineligible for stem cell transplant, included 72 patients from the UK.

11 Dec 2013

Immunologists receive $4.8M grant to target multiple diseases by manipulating enzyme

Immunologists Barbara A. Osborne and Lisa M. Minter at the University of Massachusetts Amherst, as part of a multi-institution research team, will share a five-year, $4.8 million National Cancer Institute grant to target multiple diseases including cancer, Alzheimer's and graft-versus-host disease (GVHD) by manipulating an enzyme that activates over 100 different protein substrates in the body.

10 Dec 2013

Researchers develop new drug-eluting contact lens for prolonged delivery of glaucoma medication

For nearly half a century, contact lenses have been proposed as a means of ocular drug delivery that may someday replace eye drops, but achieving controlled drug release has been a significant challenge.

10 Dec 2013

Takeda presents clinical study results of oral proteasome inhibitor MLN9708 in multiple myeloma patients

Takeda Pharmaceutical Company Limited today announced final Phase 1 and preliminary Phase 2 results of a study combining oral investigational MLN9708 administered twice a week with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma.

10 Dec 2013

IBN and IBM discover new medical application for converted PET bottles

Researchers at Singapore's Institute of Bioengineering and Nanotechnology (IBN) and California's IBM Research - Almaden (IBM) have discovered a new, potentially life-saving application for polyethylene terephthalate (PET), which is widely used to make plastic bottles.

10 Dec 2013

Growing cord blood stem cells in lab before transplant boosts survival, study finds

Donated umbilical cord blood contains stem cells that can save the lives of patients with leukemia, lymphoma and other blood cancers.

9 Dec 2013

Transplant News and Research

SynCardia Systems raises $14M to fund the rapid growth of Total Artificial Heart

BWH receives $140M grant from NIAID to support ongoing research led by AIDS Clinical Trial Group

Women are more susceptible to damaging effects of alcohol than men

Research roundup: Long-term care use varies dramatically by state; health spending slowdown explained

Groundbreaking UVA research receives $3.3M NIH grant to increase lungs for transplantation

New reports demonstrate the effectiveness of modified T cells in treating blood-borne cancers

Findings help inform ongoing discussions regarding potential changes to US' lung allocation policy

New guidelines to manage heart failure in children

Emergent BioSolutions enters into definitive agreement to acquire Cangene

New guidelines developed to manage heart failure in children with undiagnosed heart disease

Researchers awarded $25 million NIH grant to study critical limb ischemia treatment

Researchers find decreased energy metabolism in heart cells as significant independent risk factor

SynCardia Systems sets new record with 150th implant of temporary Total Artificial Heart

Study shows children with ALL can safely receive intravenous infusions of chemotherapy

Celgene: FIRST trial meets primary endpoint in patients newly diagnosed with multiple myeloma

Immunologists receive $4.8M grant to target multiple diseases by manipulating enzyme

Researchers develop new drug-eluting contact lens for prolonged delivery of glaucoma medication

Takeda presents clinical study results of oral proteasome inhibitor MLN9708 in multiple myeloma patients

IBN and IBM discover new medical application for converted PET bottles

Growing cord blood stem cells in lab before transplant boosts survival, study finds

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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