Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Life's Essential 8: Higher cardiovascular health scores linked to reduced mortality risks

Cardiovascular disease (CVD) is one of the most significant causes of global mortality. Several factors, such as obesity, poor diet, lack of physical activity, dyslipidemia, smoking, diabetes, and high blood pressure, have been identified to enhance the risk of CVD events. In 2010, the American Heart Association (AHA) constructed Life’s Simple 7, which included seven lifestyle-based goals that could help achieve ideal cardiovascular health (CVH).

4 Apr 2023

New review examines link between HDLC and different types of cancer

Researchers summarized studies on the association between high-density lipoprotein cholesterol and different types of cancer

29 Mar 2023

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

A new research paper was published in Oncotarget's Volume 14 on March 24, 2023, entitled, "Downregulation of angulin-1/LSR induces malignancy via upregulation of EGF-dependent claudin-2 and TGF-β-dependent cell metabolism in human lung adenocarcinoma A549 cells."

29 Mar 2023

Capsaicin and its health benefits

Researchers examine the health benefits associated with capsaicin, with a particular focus on how this compound impacts cognition and cardiovascular health.

28 Mar 2023

Losing weight with lifestyle changes may reduce cardiovascular risk- even if some weight is regained

Losing weight with lifestyle changes in an intensive behavioral weight loss program was associated with a decrease in risk factors for cardiovascular disease and Type 2 diabetes for at least five years -; even if some weight was regained, according to a systematic review of research, published today in Circulation: Cardiovascular Quality and Outcomes, a peer-reviewed American Heart Association journal.

28 Mar 2023

Despite raising LDL levels, coffee lowers systolic and diastolic blood pressure

Researchers performed a cross-sectional analysis of the general population of Hamburg City, Germany.

27 Mar 2023

Complications, pathophysiology, and treatment of type 2 diabetes differ by sex

In a recent review published in the journal Diabetologia, researchers in Austria discussed the sex-based differences in the risk factors, diagnosis, and therapeutic approaches for type 2 diabetes and associated complications to improve awareness about and management options for all diabetes type 2 patients.

22 Mar 2023

New study investigates effect of short-term PM2.5 exposure on blood lipids

A recent Scientific Reports study sought to address a gap in research and determined the association between short-term PM2.5 exposure and blood lipids.

22 Mar 2023

New VA Medical Center program to help veterans with atherosclerotic cardiovascular disease

More than 2 million veterans are living with atherosclerotic cardiovascular disease (ASCVD) and require management of their high cholesterol, according to the Department of Veterans Affairs (VA).

21 Mar 2023

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Researchers investigate the impact of intestinal microbiota dysbiosis on atherosclerotic cardiovascular disease incidence.

15 Mar 2023

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Houston Methodist scientists reversed infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein, showing further evidence that links high cholesterol to female infertility.

15 Mar 2023

Consuming low-insulin-stimulating bread significantly reduces body weight

Substituting common insulinogenic bread with bread releasing low levels of inulin could significantly reduce weight among obese individuals.

13 Mar 2023

Dietary polyphenol intake reduces risk of metabolic syndrome

Researchers investigate the relationship between dietary polyphenol intake and metabolic syndrome.

10 Mar 2023

Investigating treat-to-target low-density lipoprotein-cholesterol versus high-intensity statins for coronary artery disease

In a recent study published in JAMA, researchers investigated whether treat-to-target (TTT) low-density lipoprotein-cholesterol (LDL-C) therapy was inferior to administering statins of high intensity for clinical outcomes in the long term among coronary artery disease (CAD) patients.

8 Mar 2023

Does treatment status relate to other diseases in gout patients?

A new study shows how urate-lowering therapy (ULT) is related to such conditions as chronic kidney disease (CKD) and cardiovascular disease (CVD).

8 Mar 2023

Statin-related residual inflammation predicts cardiovascular events and mortality

A recent Lancet study assessed the importance of low-density lipoprotein cholesterol (LDLC) and high-sensitivity C-reactive protein (CRP) as risk predictors of cardiovascular death, cardiovascular events, and all-cause death among patients subjected to statins.

7 Mar 2023

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

New research has shown that the blood vessels that feed aggressive brain tumors have receptors that could allow a new type of drug-containing nanoparticle to be used to starve the tumors of the energy they use to grow and spread, and also cause other disruptions to their adapted existence, even killing themselves.

7 Mar 2023

What is the impact of consuming walnuts on the dietary intake of total polyphenols?

Researchers performed secondary analyses of the Walnuts and Healthy Aging study (WAHA) data.

7 Mar 2023

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

MK-0616, an experimental oral proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitor, met its primary endpoint and substantially reduced levels of low-density lipoprotein (LDL) cholesterol in people with high cholesterol and/or heart disease related to clogged arteries, in a study being presented at the American College of Cardiology's Annual Scientific Session Together With the World Congress of Cardiology.

6 Mar 2023

Review highlights the effectiveness of diet-based low-density lipoprotein lowering over medication

In a recent article published in the journal Nutrition, researchers in Australia summarized how diet could help decrease low-density lipoprotein cholesterol (LDLc) or triglyceride concentrations in polygenic hypercholesterolemia.

5 Mar 2023

Lipoprotein News and Research

Further Reading

Life's Essential 8: Higher cardiovascular health scores linked to reduced mortality risks

New review examines link between HDLC and different types of cancer

Study investigates how loss of angulin-1/LSR affects the malignancy of lung adenocarcinoma

Capsaicin and its health benefits

Losing weight with lifestyle changes may reduce cardiovascular risk- even if some weight is regained

Despite raising LDL levels, coffee lowers systolic and diastolic blood pressure

Complications, pathophysiology, and treatment of type 2 diabetes differ by sex

New study investigates effect of short-term PM2.5 exposure on blood lipids

New VA Medical Center program to help veterans with atherosclerotic cardiovascular disease

The relationship between intestinal microbiome dysbiosis and atherosclerosis

Reversing infertility in sterile mice by reducing high-circulating cholesterol with a bacterial protein

Consuming low-insulin-stimulating bread significantly reduces body weight

Dietary polyphenol intake reduces risk of metabolic syndrome

Investigating treat-to-target low-density lipoprotein-cholesterol versus high-intensity statins for coronary artery disease

Does treatment status relate to other diseases in gout patients?

Statin-related residual inflammation predicts cardiovascular events and mortality

Study reveals the LDLR pathway as a ubiquitous metabolic vulnerability in high grade gliomas

What is the impact of consuming walnuts on the dietary intake of total polyphenols?

LDL cholesterol levels reduced by oral PCSK9 inhibitor in phase 2 trial

Review highlights the effectiveness of diet-based low-density lipoprotein lowering over medication

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