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Newly identified protein markers could signal early development of metastatic lung cancer

Researchers at Mays Cancer Center at The University of Texas Health Science at San Antonio (UT Health San Antonio) have identified protein markers that could signal for early development of metastatic lung cancer, providing possibilities for new treatment.

4 Oct 2023

New drug tirzepatide equally effective in early-onset and later-onset type 2 diabetes

Tirzepatide is as effective at treating early-onset type 2 diabetes (T2D), a more aggressive form of the condition that normally responds less well to treatment, as it is at treating T2D diagnosed later in life, new research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) has found.

4 Oct 2023

Organ-on-chip model sheds light on lymphedema

In a new PNAS study co-authored by Boston University biomedical engineer Dr. Chris Chen, researchers say they're getting closer to understanding the mysteries of lymphedema -; a condition characterized by the buildup of fluid in the body due to a malfunctioning lymphatic system.

4 Oct 2023

Study finds cluster of common conditions may signal early onset of type 2 diabetes

New research presented at this year's Annual Meeting of The European Association for the Study of Diabetes (EASD), Hamburg (2-6 Oct), reveals a marked increase in several common conditions in the years leading up to, and immediately prior to, type 2 diabetes diagnosis, suggesting considerably earlier diagnosis might be possible in some patients.

4 Oct 2023

How vitamin D and genetics shape early brain development

The study examined how vitamin D levels and vitamin D binding protein genotypes in both pregnant mothers and their children aged 3-5, impact early childhood neurodevelopment. Findings suggest that higher vitamin D concentrations in children were associated with better neurodevelopmental scores, with additional influences from sociodemographic factors and certain genetic variations.

4 Oct 2023

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

An oral lipid nanoparticle drug prevents tumor development in mice, suggesting this is a promising drug formulation for preventing colitis-associated cancer, according to a study led by researchers in the Institute for Biomedical Sciences at Georgia State University.

4 Oct 2023

The adipose tissue dysfunction behind metabolically healthy obesity

A session at this year's Annual Meeting of the European Association for the Study of Diabetes will explore the latest data on the concept of metabolically healthy obesity (MHO) – more commonly known by the public as 'fat but fit'.

4 Oct 2023

Study links high and low levels of "good" cholesterol with dementia risk

Having either high or low levels of high-density lipoprotein (HDL) cholesterol, or "good" cholesterol, is tied to a small increased risk of dementia in older adults, according to a study published in the October 4, 2023, online issue of Neurology, the medical journal of the American Academy of Neurology.

4 Oct 2023

Measuring ctDNA may lead to alternative treatment options for BRAF wild-type melanoma

Circulating tumor DNA (ctDNA) is emerging as a blood-based biomarker for many solid tumor types, including melanoma.

4 Oct 2023

Dietary deep dive: Unveiling the good, the bad, and the unclear in blood pressure battleground

An umbrella review in Advances in Nutrition critically analyzes various dietary elements' effects on blood pressure and hypertension, revealing a spectrum of impacts across different food groups and nutrients. While certain diets and foods like DASH, ketogenic, and flaxseed show promise in blood pressure control, the evidence varies widely, urging further research to refine existing hypertension dietary guidelines.

4 Oct 2023

Research identifies characteristics linked with higher risk of sudden cardiac arrest in people with type 2 diabetes

New research being presented at the Annual Meeting of the European Association for the Study of Diabetes (EASD) in Hamburg, Germany (2-6 Oct) has identified a range of characteristics associated with a higher risk of sudden cardiac arrest in individuals with type 2 diabetes.

4 Oct 2023

Study identifies potential new way to protect premature babies from deadly infection

Premature babies in neonatal care units are extremely vulnerable, and susceptible to life-threatening infections.

4 Oct 2023

Early metformin therapy falls short in curbing gestational diabetes woes

In a significant randomized clinical trial, early metformin therapy was tested for its potential to lessen insulin dependence and enhance glycemic control in gestational diabetes-afflicted pregnant women; however, it yielded no improvements in diabetes symptoms. While metformin reduced maternal weight gain, its effects on primary diabetes symptoms and other secondary outcomes like infant weight gain were mixed, indicating a need for further focused research to unravel these associations.

4 Oct 2023

Effectiveness of Lactobacillus in treating inflammatory bowel disease

The role of Lactobacillus in treating inflammatory bowel disease.

4 Oct 2023

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

Researchers investigated endotype-phenotype associations in atopic dermatitis (AD) beyond its general clinical severity.

4 Oct 2023

The cut-off for HbA1c-based diagnosis of diabetes may be too high in women

Researchers compare the distribution of glycated hemoglobin (HbA1c) levels in premenopausal women and men of the same age.

4 Oct 2023

New study reveals inequalities in the provision of heart valve replacement surgery

There are striking inequalities in the provision of major (aortic) heart valve replacement surgery across England, with women, Black and Asian people, and those living in areas of deprivation much less likely to receive the life-saving procedure, suggests a large data analysis, published in the open access journal Open Heart.

4 Oct 2023

Blood News and Research

Newly identified protein markers could signal early development of metastatic lung cancer

New drug tirzepatide equally effective in early-onset and later-onset type 2 diabetes

Organ-on-chip model sheds light on lymphedema

Study finds cluster of common conditions may signal early onset of type 2 diabetes

How vitamin D and genetics shape early brain development

Oral lipid nanoparticle drug shows promise for preventing colitis-associated cancer in mice

The adipose tissue dysfunction behind metabolically healthy obesity

Study links high and low levels of "good" cholesterol with dementia risk

Measuring ctDNA may lead to alternative treatment options for BRAF wild-type melanoma

Dietary deep dive: Unveiling the good, the bad, and the unclear in blood pressure battleground

Research identifies characteristics linked with higher risk of sudden cardiac arrest in people with type 2 diabetes

Study identifies potential new way to protect premature babies from deadly infection

Early metformin therapy falls short in curbing gestational diabetes woes

Effectiveness of Lactobacillus in treating inflammatory bowel disease

Study highlights the patient heterogeneity in atopic dermatitis and demonstrates the promises of personalized treatment

The cut-off for HbA1c-based diagnosis of diabetes may be too high in women

New study reveals inequalities in the provision of heart valve replacement surgery

What mobile clinics in dollar general parking lots say about health care in rural America

Can human chorionic gonadotropin supplements enhance penile growth?

Unveiling the role of astrocyte-derived LCN2 in neurodegenerative disease progression

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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