Antibodies News and Research

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Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Researchers discuss mutations in the NTD of the spike protein, which contains an antigenic “supersite” and is the target for nAbs.

24 Oct 2021

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Researchers report the binding and pseudo-neutralizing antibody titers elicited after patients had received either the Pfizer-BioNTech or AstraZeneca vaccines.

24 Oct 2021

Fluorescent system reveals how viruses produced during RSV infection change shape

Respiratory syncytial virus, more commonly known as RSV, is a highly contagious respiratory virus that can be very serious and even fatal for young children and the elderly.

22 Oct 2021

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

A team of researchers measured the infectivity of SARS-CoV-2 variants C.1.2, Mu, and Delta+501S spike proteins and determined the susceptibility to neutralizing antibodies.

22 Oct 2021

SARS-CoV-2 anti-nucleocapsid antibodies reduce risk of reinfection for at least eight months

A new study concludes that at least with predominantly wild-type variants, the risk of reinfection with the virus among unvaccinated people is reduced by 80% or more.

22 Oct 2021

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Scientists studied the efficacy of an intranasal booster composed of beta variant-spike protein S1 with IL-15 and TLR agonists in macaques that were previously immunized.

22 Oct 2021

Replication of SARS-CoV-2 variants in different cell and organ models

In this study, the replication of B.1.1.7 viruses was analyzed in different cell and organ models and dwarf hamsters.

22 Oct 2021

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

Researchers from Stanford University have been attempting to create a hydrogel-based vaccine delivery system that could improve the immune response's strength and duration.

22 Oct 2021

TEDDY study adds to a growing body of evidence that type 1 diabetes is not a single disease

New findings from the international The Environmental Determinants of Diabetes in the Young (TEDDY) study add to a growing body of evidence indicating that type 1 diabetes is not a single disease. The presentation and, perhaps, cause of autoimmune diabetes differs among genetically high-risk children, the research suggests.

22 Oct 2021

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Amidst growing concerns on the use and potential benefits of convalescent plasma therapy, a research group in the United States has identified three human antibodies (Abs) that, when combined, demonstrate both robust viral suppressive properties against all tested severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Variants of Concern (VoC) in vitro and profound antiviral efficacy in vivo.

22 Oct 2021

Investigational inhaled COVID-19 treatment graduates to phase 3 in ACTIV-2 trial

The AIDS Clinical Trials Group, the largest global HIV research network, which recently expanded its focus to include evaluating outpatient treatment for COVID-19, today announced that the external data and safety monitoring board (DSMB) has recommended that SNG001, an inhaled formulation of interferon beta, advance to phase 3 in the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial (ACTG A5401).

21 Oct 2021

Nationwide advertising campaign launches in the UK to urge people to get COVID-19 booster, flu jabs

A nationwide advertising campaign launches today (Friday 22 October) as part of the government's call to the public to get their COVID-19 booster and flu jabs, to protect themselves and their loved ones this winter.

21 Oct 2021

Booster dose of COVID-19 vaccine significantly increases neutralizing antibodies in rhesus macaques

A booster dose of the mRNA-1273 COVID-19 vaccine given to rhesus macaques about six months after their primary vaccine series significantly increased levels of neutralizing antibodies against all known SARS-CoV-2 variants of concern, according to a new study from National Institutes of Health scientists and colleagues.

21 Oct 2021

Antibodies News and Research

Immune evasion by SARS-CoV-2 facilitated by a mutational hotspot in the NTD

Does previous SARS-CoV-2 infection affect vaccine-induced immunity?

Fluorescent system reveals how viruses produced during RSV infection change shape

Mu and C.1.2 variant spike proteins partially resistant to neutralization by vaccine-elicited antibodies

SARS-CoV-2 anti-nucleocapsid antibodies reduce risk of reinfection for at least eight months

Immunogenicity and efficacy of adjuvanted SARS-CoV-2 beta variant subunit booster in rhesus macaques

Replication of SARS-CoV-2 variants in different cell and organ models

Hydrogel-based vaccine delivery system evokes antibody response against SARS-CoV-2

TEDDY study adds to a growing body of evidence that type 1 diabetes is not a single disease

SARS-CoV-2 cocktail with three antibodies potent in preclinical testing

Investigational inhaled COVID-19 treatment graduates to phase 3 in ACTIV-2 trial

Nationwide advertising campaign launches in the UK to urge people to get COVID-19 booster, flu jabs

Booster dose of COVID-19 vaccine significantly increases neutralizing antibodies in rhesus macaques

Development of a plant-based platform for the production of SARS-CoV-2 antigen

Immune responses to SARS-CoV-2 infection and vaccination in patients with multiple sclerosis

Researchers develop a new method to remove old cells from tissues to slow down aging

Broadly protective vaccines against coronaviruses needed to protect against future outbreaks

Children show lower seroconversion rates than adults with mild COVID-19

New research on phagocytosis and SARS-CoV-2's spike protein

The neutralization potential of nanobodies against SARS-CoV-2

How to make hybridoma-based antibody discovery more efficient eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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