Immune System News and Research

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Scientists seek to block pathogen’s most reliable weapon to cause severe malaria

The parasites that cause severe malaria are well-known for the sinister ways they infect humans, but new research may lead to drugs that could block one of their most reliable weapons: interference with the immune response.

21 Jul 2021

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

You can't make a banana split without bananas. And you can't generate stable regulatory T cells without Vitamin C or enzymes called TET proteins, it appears.

21 Jul 2021

Scientists identify gut microbiota dysbiosis as a potential risk factor for long COVID

A study in Norway has recently highlighted a significant association between gut microbiota alteration and persistent respiratory dysfunction in coronavirus disease 2019 (COVID-19) patients.

21 Jul 2021

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

In a new University of California, Irvine-led study, researchers found that a certain protein prevented regulatory T cells (Tregs) from effectively doing their job in controlling the damaging effects of inflammation in a model of multiple sclerosis (MS), a devastating autoimmune disease of the nervous system.

20 Jul 2021

UMD receives funding to enhance quality of pork production through improved muscle growth in pigs

The University of Maryland received funding from the United States Department of Agriculture National Institute of Food and Agriculture to enhance the overall quality and efficiency of pork production through improved muscle growth in pigs.

20 Jul 2021

Exhausted T cells linked to increased risk of COVID-19 mortality

New research led by Nadia R. Roan of Gladstone Institutes and the University of California, San Francisco, finds a correlation between high numbers of inflammatory CXCR4+ T cells and regulatory T cells specific to SARS-CoV-2 and dying from infection. In contrast, people who recovered from severe COVID-19 illness were more likely to have many SARS-CoV-2-specific T cells that perform homeostatic proliferation.

20 Jul 2021

Antibody levels remain high nine months after SARS-CoV-2 infection, study shows

Testing of an entire Italian town shows antibody levels remain high nine months after SARS-CoV-2 infection, whether symptomatic or asymptomatic.

19 Jul 2021

T cells can be engineered to fight tumors without succumbing to exhaustion

Fighting a tumor is a marathon, not a sprint. For cancer-fighting T cells, the race is sometimes just too long, and the T cells quit fighting. Researchers even have a name for this phenomenon: T cell exhaustion.

19 Jul 2021

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

In February 2020, a trio of bio-imaging experts were sitting amiably around a dinner table at a scientific conference in Washington, D.C., when the conversation shifted to what was then a worrying viral epidemic in China.

19 Jul 2021

Researchers use appendiceal cancer organoids to study personalized immunotherapy response

Wake Forest researchers and clinicians are using patient-specific tumor 'organoid' models as a preclinical companion platform to better evaluate immunotherapy treatment for appendiceal cancer, one of the rarest cancers affecting only 1 in 100,000 people.

19 Jul 2021

A low-cost biopolymer dressing to help heal chronic wounds

Tens of millions of patients around the world suffer from persistent and potentially life-threatening wounds. These chronic wounds, which are also a leading cause of amputation, have treatments, but the cost of existing wound dressings can prevent them from reaching people in need.

19 Jul 2021

New research may offer clues to why MS patients develop progressive disability

Did you know multiple sclerosis (MS) means multiple scars? New research shows that the brain and spinal cord scars in people with MS may offer clues to why they developprogressive disability but those with related diseases where the immune system attacks the central nervous system do not.

19 Jul 2021

Study: Second dose of COVID-19 vaccine induces a powerful boost to the immune system

The second dose of a COVID-19 vaccine induces a powerful boost to a part of the immune system that provides broad antiviral protection, according to a study led by investigators at the Stanford University School of Medicine.

19 Jul 2021

Researchers discover major metabolite involved in regulating intestinal bacteria

Researchers at the RIKEN Center for Integrative Medical Sciences (IMS) have discovered that acetate, a major metabolite produced by some intestinal bacteria, is involved in regulating other intestinal bacteria.

19 Jul 2021

Dysbiosis in gut microbiota may cause severe secondary infection in COVID-19 patients

An interesting study led by scientists in the U.S. has recently revealed that the microbial community in the gut is directly affected by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and that virus-mediated gut microbiome dysbiosis may cause severe secondary infections in coronavirus disease 2019 (COVID-19) patients. The study is currently available on the bioRxiv* preprint server.

19 Jul 2021

Stronger and longer SARS-CoV-2 RBD-ACE2 binding associated with glycans in new study

A new study has been published on the bioRxiv* preprint server, which focuses on the mechanism behind the binding of SARS-CoV-2 with the host receptor, using a molecular dynamics approach. The authors of this study aim to highlight the role of glycans in initiating the interaction between S and ACE2.

19 Jul 2021

Immune System News and Research

Scientists seek to block pathogen’s most reliable weapon to cause severe malaria

Vitamin C and TET proteins can work together to give regulatory T cells their life-saving power

Scientists identify gut microbiota dysbiosis as a potential risk factor for long COVID

Targeting Piezo1 protein may be a new and ideal strategy to cure multiple sclerosis

UMD receives funding to enhance quality of pork production through improved muscle growth in pigs

Exhausted T cells linked to increased risk of COVID-19 mortality

Antibody levels remain high nine months after SARS-CoV-2 infection, study shows

T cells can be engineered to fight tumors without succumbing to exhaustion

Scientists deconstruct the protein-based machine responsible for SARS-CoV-2 replication

Researchers use appendiceal cancer organoids to study personalized immunotherapy response

A low-cost biopolymer dressing to help heal chronic wounds

New research may offer clues to why MS patients develop progressive disability

Study: Second dose of COVID-19 vaccine induces a powerful boost to the immune system

Researchers discover major metabolite involved in regulating intestinal bacteria

Dysbiosis in gut microbiota may cause severe secondary infection in COVID-19 patients

Stronger and longer SARS-CoV-2 RBD-ACE2 binding associated with glycans in new study

Researchers isolate human monoclonal antibodies that may neutralize several norovirus variants

UCSF researchers discover how the immune system may play a role in miscarriage

Researchers identify novel disorder resulting from a mutation in AIOLOS protein

UK study finds brain or nerve complications in 1 in 20 of children hospitalized with COVID-19

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