Transplant News and Research

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Scientists to combine NK cell therapy with immunocytokine to target childhood cancer

Researchers have made rapid advances in understanding how to manipulate the immune system safely to destroy cancer cells. Adoptive transfer of haploidentical natural killer cells has shown promise as a treatment option to target and kill cancer cells in a less toxic way than conventional therapies. Now for the first time, scientists will combine NK cell therapy with an immunocytokine to target children with relapsed/refractory disease including those with bulky tumors.

11 Oct 2013

Hispanics with kidney failure are less likely to receive kidney transplant due to living location

In the United States, Hispanics with kidney failure are less likely than non-Hispanic whites to receive a kidney transplant largely due to their blood type and because of where they live, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN).

11 Oct 2013

Less educated, African Americans receive lower quality or marginal kidneys for transplantation

Among younger kidney transplant recipients, a disproportionate number of African Americans and individuals with less education receive organs that are of lower quality or are considered marginal, according to a study appearing in an upcoming issue of the Clinical Journal of the American Society of Nephrology (CJASN). The findings suggest that there are racial and social disparities in the allocation of transplanted organs that need to be addressed.

11 Oct 2013

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Researchers at the University of California, San Diego School of Medicine have identified 13 metabolites - small molecules produced by cellular metabolism - that are significantly different in patients with diabetes and chronic kidney disease compared to healthy controls.

11 Oct 2013

Cleveland healthcare institutions receive $1M grant to develop Stroke Clinical Trials Coordinating Center

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11 Oct 2013

Liposorber LA-15 System to treat pediatric patients with primary FSGS gets FDA approval

The U.S. Food and Drug Administration today approved Liposorber LA-15 System to treat pediatric patients with primary focal segmental glomerulosclerosis either before transplant, or after renal (kidney) transplantation in which there is recurrence of FSGS.

11 Oct 2013

Combining gene therapy with stem cells leads to faster healing of burns

Johns Hopkins researchers, working with elderly mice, have determined that combining gene therapy with an extra boost of the same stem cells the body already uses to repair itself leads to faster healing of burns and greater blood flow to the site of the wound.

10 Oct 2013

Promedior starts Phase 2 clinical trial to evaluate PRM-151 in patients with myelofibrosis

Promedior, Inc., a clinical stage biotechnology company developing novel biologic therapeutics for the treatment of fibrosis, announced today that it has initiated a Phase 2 clinical trial to evaluate PRM-151, its lead product candidate, in patients with myelofibrosis.

10 Oct 2013

Compugen drug candidate prevents autoimmune type I diabetes in animal model

Compugen Ltd., announced today that CGEN-15001, an Fc fusion protein drug candidate derived from a novel immune checkpoint protein discovered by Compugen, has been shown to be highly efficient in preventing the development of disease in a well-accepted animal model of autoimmune type I diabetes, known also as juvenile diabetes.

9 Oct 2013

New method for improving cord blood transplant success

Starting with a discovery in zebrafish in 2007, Harvard Stem Cell Institute researchers have published initial results of a Phase Ib human clinical trial of a therapeutic that has the potential to improve the success of blood stem cell transplantation.

9 Oct 2013

New research identifies protein that controls formation of different types of mature blood cells

New research in the Journal of Experimental Medicine identifies a protein that controls the formation of different types of mature blood cells - a finding that could be important to developing new treatments for blood diseases and helping realize the potential of regenerative medicine.

8 Oct 2013

Kiadis Pharma signs Services Agreement with GRCBDS for Phase II clinical study with ATIR

Kiadis Pharma B.V., a clinical stage biopharmaceutical company developing treatments for blood cancers, announced today that a Services Agreement has been signed with the German Red Cross Blood Donor Service Baden-Wuerttemberg-Hessen (GRCBDS) whereby GRCBDS will provide pharmaceutical development and GMP manufacturing services for Kiadis Pharma's ongoing Phase II clinical study with ATIR™.

7 Oct 2013

Six prominent surgeons awarded Honorary Fellowship at Clinical Congress of ACS

Last night Honorary Fellowship in the American College of Surgeons (ACS) was awarded to six prominent surgeons from Germany, England, Thailand, Mexico, and Malaysia during the Convocation ceremony that preceded the official opening of the 2013 Clinical Congress of the American College of Surgeons.

7 Oct 2013

Winners of VCCircle Healthcare Awards announced

The event recognised medical professionals who have not only scaled in terms of clinical and financial performance but also played a role in making a difference in patients' lives.

7 Oct 2013

Researchers suggest new view of how stem cells may help repair brain following trauma

University of South Florida researchers have suggested a new view of how stem cells may help repair the brain following trauma. In a series of preclinical experiments, they report that transplanted cells appear to build a "biobridge" that links an uninjured brain site where new neural stem cells are born with the damaged region of the brain.

4 Oct 2013

Substance abuse treatment before, after liver transplantation has lower alcohol relapse rates

New research reports that liver transplant recipients who receive substance abuse treatment before and after transplantation have much lower alcohol relapse rates than those untreated or only treated prior to transplantation.

4 Oct 2013

Component of grape, citrus fruits block formation of kidney cysts

A new study published today in British Journal of Pharmacology has identified that a component of grapefruit and other citrus fruits, naringenin, successfully blocks the formation of kidney cysts.

3 Oct 2013

Saint Luke's liver transplantation program receives CMS certification

The liver transplantation program at Saint Luke's Hospital of Kansas City has received certification by the Centers for Medicare and Medicaid. The certification is an important step in enhancing the hospital's ability to care for Medicare-covered patients suffering from end-stage liver disease, and attract other insurers who base their coverage on the CMS certification.

2 Oct 2013

Researchers develop renal risk index to predict post-transplant end-stage renal disease

End-stage renal disease is one of the major public health problems among solid organ transplant recipients that is associated with death after transplant and high cost of care.

2 Oct 2013

Data from Boehringer Ingelheim's HCV clinical program accepted for presentation at The Liver Meeting

New data from Boehringer Ingelheim's hepatitis C virus clinical development program have been accepted for presentation at the 64th Annual Meeting of the American Association for the Study of Liver Diseases, also known as The Liver Meeting®, taking place November 1-5 in Washington, D.C.

1 Oct 2013

Transplant News and Research

Scientists to combine NK cell therapy with immunocytokine to target childhood cancer

Hispanics with kidney failure are less likely to receive kidney transplant due to living location

Less educated, African Americans receive lower quality or marginal kidneys for transplantation

Suppression of mitochondria: A dominant feature of diabetic kidney disease

Cleveland healthcare institutions receive $1M grant to develop Stroke Clinical Trials Coordinating Center

Liposorber LA-15 System to treat pediatric patients with primary FSGS gets FDA approval

Combining gene therapy with stem cells leads to faster healing of burns

Promedior starts Phase 2 clinical trial to evaluate PRM-151 in patients with myelofibrosis

Compugen drug candidate prevents autoimmune type I diabetes in animal model

New method for improving cord blood transplant success

New research identifies protein that controls formation of different types of mature blood cells

Kiadis Pharma signs Services Agreement with GRCBDS for Phase II clinical study with ATIR

Six prominent surgeons awarded Honorary Fellowship at Clinical Congress of ACS

Winners of VCCircle Healthcare Awards announced

Researchers suggest new view of how stem cells may help repair brain following trauma

Substance abuse treatment before, after liver transplantation has lower alcohol relapse rates

Component of grape, citrus fruits block formation of kidney cysts

Saint Luke's liver transplantation program receives CMS certification

Researchers develop renal risk index to predict post-transplant end-stage renal disease

Data from Boehringer Ingelheim's HCV clinical program accepted for presentation at The Liver Meeting

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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