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Researchers decipher antitumor mechanism of Amazonian plant in human cancer cells

A piece of research conducted by the Free Radicals and Oxidative Stress Group at the UPV/EHU's Faculty of Medicine and Nursing has deciphered the antitumor mechanism exerted by the plant Vismia baccifera, originally from the Amazonian region of Colombia, in human liver cancer cells.

28 Sep 2018

Researchers uncover molecular underpinnings of liver regeneration

In Greek mythology, Zeus punishes the trickster Prometheus by chaining him to a rock and sending an eagle to eat a portion of his liver every day, in perpetuity. It was the right organ to target - the liver has the ability to regenerate itself, though not overnight nor for eternity.

27 Sep 2018

Novel mathematical approach uncovers existence of unsuspected biological cycles

A novel mathematical approach has uncovered that some animal cells have robust 12-hour cycles of genetic activity, in addition to circadian or 24-hour cycles.

20 Sep 2018

Researchers describe cell mechanism that optimizes proteins production in stressful situations

The different genes within the genome must be expressed in precise levels and in the exact moment if the complex balance regulating cell activity is to be maintained.

19 Sep 2018

Investigators pinpoint exact stage of retinoblastoma development in children

Investigators at Children's Hospital Los Angeles have been able to pinpoint the exact stage of development of the human retina, when cells can grow out of control and form cancer-like masses.

14 Sep 2018

Study: Healthy diet could help promote healthy cellular aging in women

Eating a diet that is rich in fruits, vegetables and whole grains and low in added sugar, sodium and processed meats could help promote healthy cellular aging in women, according to a new study published in the American Journal of Epidemiology.

21 Aug 2018

Study unravels cellular and molecular mechanisms behind dermal condensate formation

Hair growth is regulated by a small cluster of hair-specific fibroblasts, the dermal papilla. But exactly how dermal papilla forms has remained elusive until now.

20 Aug 2018

Scientists uncover key control mechanism of DNA replication

Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to prevent diseases or cancer.

16 Aug 2018

Hearts of newborn piglets can completely heal after heart attacks

While pigs still cannot fly, researchers have discovered that the hearts of newborn piglets do have one remarkable ability. They can almost completely heal themselves after experimental heart attacks.

15 Aug 2018

Alzheimer's drug may prevent disease progression if used before symptoms appear

About 50 percent of people who reach the age of 85 will develop Alzheimer's disease. Most will die within about five years of exhibiting the hallmark symptoms of the disease - severe memory loss and a precipitous decline in cognitive function.

2 Aug 2018

Fruit fly research leads to potential drug for debilitating diseases caused by parasitic worms

River blindness and elephantiasis are debilitating diseases caused by parasitic worms that infect as many as 150 million people worldwide.

13 Jul 2018

Study demonstrates new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine (IRB Barcelona) report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets. The study has been published in the journal EMBO Molecular Medicine.

12 Jul 2018

Scientists pinpoint new therapeutic targets for inflammation-associated colon cancer

Scientists headed by ICREA researcher Angel R. Nebreda at the Institute for Research in Biomedicine report a new mechanism that contributes to the development of inflammation-associated colon cancer and points to new therapeutic targets

11 Jul 2018

New approach sheds light on effects of drugs on cancer cells

A new approach established at the University of Zurich sheds light on the effects of anti-cancer drugs and the defense mechanisms of cancer cells.

11 Jul 2018

Study: Administration of endocrine disruptor causes epigenetic changes in pregnant sow's DNA

The public debate on endocrine disrupting chemicals- exogenous substances that have the same or similar effects as endogenous hormones - has been going on for some time.

30 Jun 2018

Mice study opens new avenues to develop therapies for growth disorders

Maintaining equal growth rates in opposing limbs is crucial for animals to achieve a symmetrical adult form; what happens if something goes wrong with one limb during development?

27 Jun 2018

Canadian researchers uncover new molecular mechanism to stop proliferation of cancer cells

Canadian researchers have discovered a new and direct molecular mechanism to stop cancer cells from proliferating. In the prestigious journal Nature Cell Biology, scientists from Université de Montréal show that a disruption of a fine balance in the composition of ribosomes (huge molecules that translate the genetic code into proteins) results in a shutdown of cancer cell proliferation, triggering a process called senescence.

26 Jun 2018

Coffee and the heart – four strong cups a day is beneficial finds study

According to a new study four cups of strong coffee might be the amount that would keep the hearts of older adults healthy. The latest study titled, “CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system—New mode of action for caffeine,” was published on 21st of June 2018 in the journal PLOS Biology.

25 Jun 2018

Four cups of coffee a day shown to protect heart muscle

A new study has shown that drinking four cups of coffee a day can protect against heart muscle damage, through the effect of caffeine on a protein called p27.

22 Jun 2018

Scientists shed light on key aspect of healthy cell division

Scientists have shed light on a key aspect of healthy cell division, helping build a clearer picture of the complex mechanisms involved.

5 Jun 2018