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COVID-19 pandemic in Africa

In a New England Journal of Medicine "Perspective" published today, Wafaa El-Sadr, MD, MPH, global director of ICAP at Columbia University Mailman School of Public Health, and Jessica Justman, MD, ICAP's senior technical director, and associate professor of epidemiology, urge a coordinated global effort in the face of the COVID-19 pandemic, with "countries around the world [taking] concrete steps to assist Africa in staying ahead of the curve, even as they confront their own epidemics."

18 Apr 2020

Gold-containing drug auranofin kills 95% of SARS-CoV-2 virus in 48 hours in lab conditions

A drug called auranofin, approved for the treatment of rheumatoid arthritis, effectively inhibits severe acute respiratory syndrome coronavirus (SARS-CoV-2) in laboratory conditions, as described in a new study by Georgia State University researchers.

16 Apr 2020

Scripps Research establishes collaborative global effort to rapidly find drugs against COVID-19

With the COVID-19 pandemic continuing to spread across the globe, Scripps Research has quickly established an international network of collaborating scientific laboratories to leverage ReFRAME, the world's leading drug repurposing collection, to find antiviral compounds against the novel coronavirus.

16 Apr 2020

Specialized proteins could soak up excess cytokines in COVID-19 patients

One of the defining features of Covid-19 is the excessive immune response that can occur in severe cases. This burst of immune overreaction, also called a cytokine storm, damages the lungs and can be fatal.

16 Apr 2020

With federal nod, consumers could lose the boost they get from drug ‘coupons’

Patients who get financial help from drug companies to cover their copayments for prescription drugs could owe a bigger chunk of their costs under a proposed federal rule.

16 Apr 2020

Remdesivir drug stops novel coronavirus from replicating

Scientists from the University of Alberta have published findings that the antiviral drug remdesivir prevents replication of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) by inhibiting RNA replication. The study, published in April 2020 in the Journal of Biological Chemistry, follows on the heels of earlier reports from the same lab in February, showing the drug's effectiveness against the related Middle East Respiratory Syndrome (MERS) virus.

15 Apr 2020

Health agencies urge continuation of life-saving measles vaccinations

The novel coronavirus disease, now officially called COVID-19, threatens the vaccination of millions of children across the globe. With most countries in lockdown and health care workers overwhelmed, many vaccination schedules have been delayed, threatening the welfare of infants and children.

15 Apr 2020

Ebola drug effective against key enzyme of coronavirus that causes COVID-19

Scientists at the University of Alberta have shown that the drug remdesivir is highly effective in stopping the replication mechanism of the coronavirus that causes COVID-19, according to new research published today in the Journal of Biological Chemistry.

13 Apr 2020

How does COVID-19 attack the body?

The coronavirus disease (COVID-19) attacks the lungs, leading to pneumonia, and eventually, a cascade of serious complications. But how does COVID-19 kill? Is it the virus itself or the result of the person’s immune system response?

13 Apr 2020

Novel coronavirus attacks and destroys T cells, just like HIV

The immune system has many components that work together in protecting the body from foreign invaders. One of the most important types of immune cells is T lymphocytes or T cells, a type of white blood cell that acts as the core of adaptive immunity, the system that modifies the immune response to specific pathogens.

13 Apr 2020

Cost of ‘repurposing’ existing drugs to treat COVID-19

The paper looks at repurposed drugs that might demonstrate efficacy against COVID-19, and if they could be manufactured profitably at very low costs to ensure affordable access to vital treatments for COVID-19 at low prices globally.

13 Apr 2020

Rockefeller and SNF announce $3 million expansion of partnership for COVID-19 research

The Rockefeller University and the Stavros Niarchos Foundation today announced a $3 million expansion of their longstanding partnership for research and medicine, bolstering Rockefeller's round-the-clock research initiatives related to COVID-19 and the SARS-CoV-2 virus that causes it.

13 Apr 2020

Arizona COVID-19 Genomics Union to study how the virus may be evolving

The Translational Genomics Research Institute, an affiliate of City of Hope, The Pathogen and Microbiome Institute at Northern Arizona University, and the Department of Ecology and Evolutionary Biology at the University of Arizona have formed a union dedicated to tracking the COVID-19 coronavirus, it was announced today.

10 Apr 2020

Top NAU microbiologist joins Arizona COVID-19 Genomics Union

The Translational Genomics Research Institute, an affiliate of City of Hope, The Pathogen and Microbiome Institute at Northern Arizona University and the Ecology and Evolutionary Biology Department at the University of Arizona have formed a union dedicated to tracking the COVID-19 coronavirus, it was announced today.

8 Apr 2020

Benefits of marijuana for pain relief are not clear-cut, study suggests

Medical marijuana users who say they have high levels of pain are more likely than those with low pain to say they use cannabis three or more times a day, a new study finds.

8 Apr 2020

Philadelphia Eagles owner contributes $1 million to Penn Medicine to fight COVID-19 pandemic

Philadelphia Eagles owner Jeffrey Lurie today announced a $1 million contribution to Penn Medicine to establish the COVID-19 Immunology Defense Fund, laying the foundation for the world's foremost experts to fight the novel coronavirus pandemic.

8 Apr 2020

Infectious diseases from animals likely to cause further pandemics

As humans move to cities to settle, there is a sharp decline in biodiversity leading to several disturbances in the balance and relationship between humans and wild animals. A new study from researchers at the University of California, Davis' One Health Institute, shows that this has led to the spread of zoonotic viruses from animals to humans, such as COVID-19, which has caused a global pandemic involving over 184 countries and territories. The study was published in the latest issue of Proceedings of the Royal Society B.

8 Apr 2020