Transplant News and Research

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Research: Larger lungs are associated with increased chance of survival

Transplant teams have long tried to match the size of donor lungs to the size of the recipient as closely as possible, concerned that lungs of the wrong size could lead to poor lung function and poor outcomes.

2 Aug 2013

Researchers reveal location of human blood stem cells that may improve bone marrow transplants

McMaster University researchers have revealed the location of human blood stem cells that may improve bone marrow transplants. The best stem cells are at the ends of the bone.

2 Aug 2013

Viropharma announces financial results for second quarter of 2013

VIROPHARMA INCORPORATED (Nasdaq: VPHM) today announced financial results for the second quarter of 2013. Net sales were $104 million for the second quarter ended June 30, 2013 as compared to $95 million in the comparative period of 2012.

1 Aug 2013

University of Iowa study links bigger lungs with improved survival for transplant patients

When it comes to lung transplants, bigger may be better. That's the main finding from a University of Iowa study, which found that oversized lungs lead to improved survival following lung transplants, particularly among patients receiving double-lung transplants.

1 Aug 2013

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

AstraZeneca and FibroGen today announced that they have entered into a strategic collaboration to develop and commercialize FG-4592, a first-in-class oral compound in late stage development for the treatment of anemia associated with chronic kidney disease and end-stage renal disease.

31 Jul 2013

Researchers study how human herpes virus packages genetic information during infection

An international collaboration of researchers including Felicia Goodrum of the University of Arizona's immunobiology department has studied how a human herpes virus carried by the majority of the population packages its genetic information during infection.

31 Jul 2013

Healthcare professionals are urged to counsel patients on healthy sex life after stroke

A new statement from American and European cardiology experts advises heart patients and their partners to receive individually tailored counseling from healthcare professionals about resuming sexual activity.

30 Jul 2013

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Genotype 1 is, worldwide, the most prevalent genotype of the hepatitis C virus. It accounts for around seventy percent of all hepatitis C infections.

30 Jul 2013

Adolescent patients who received kidney transplant appear to be at increased risk for transplant failure

Patients who received their first kidney transplant at ages 14 to 16 years appear to be at increased risk for transplant failure, with black adolescents having a disproportionately higher risk of graft failure, according to a report published by JAMA Internal Medicine, a JAMA Network publication.

30 Jul 2013

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

Call it therapeutic poop, if you will, but the best hope yet for an effective treatment of childhood infections with the drug-resistant bacterium C. difficile may come straight from the gut, according to recent research.

30 Jul 2013

NIH expands CRIC study to identify risk factors for progression of early stage CKD

Researchers from the Chronic Renal Insufficiency Cohort study are embarking on another five years of work to identify risk factors for progression of early stage chronic kidney disease, better understand the importance of reduced kidney function in older persons, and learn what role CKD may play in other illnesses that require hospitalization. CRIC is supported by the National Institutes of Health.

30 Jul 2013

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Rebiotix Inc. announced today that the U.S. Food and Drug Administration has approved the company's Investigational New Drug application to begin the Phase 2 clinical study of RBX2660 for the treatment of recurrent Clostridium difficile infection.

30 Jul 2013

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

The USPSTF agreed with the CDC that since most patients (75%) who are currently infected with hepatitis C were born between 1945 - 1965, and since risk-based screening has not been successful in identifying these individuals, that a one time age-based hepatitis C blood test was necessary.

29 Jul 2013

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

Reporters Peter Whoriskey and Dan Keating have opened Post readers' eyes to the fact that Medicare pays for physician services -; a $69.6 billion item in 2012 -; according to an arcane and little-known price list, over which doctors themselves exercise considerable and less-than-totally-transparent influence (7/24).

26 Jul 2013

Weekend reading: The mystery of some innovations that are slow to be accepted; myths about the obesity crisis

Why do some innovations spread so swiftly and others so slowly? Consider the very different trajectories of surgical anesthesia and antiseptics. ... On October 16, 1846, at Massachusetts General Hospital, Morton administered his gas through an inhaler in the mouth of a young man undergoing the excision of a tumor in his jaw. ... By February, anesthesia had been used in almost all the capitals of Europe, and by June in most regions of the world.

26 Jul 2013

Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

Gout is a relatively common arthritic disease that affects about 4% (I in 25) of the population. It results from the deposition of uric acid in joints due to elevated blood levels and a resulting inflammation ensues which is very painful.

26 Jul 2013

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

NOXXON Pharma today announced the successful completion of patient recruitment of its NOX-E36 Phase IIa clinical trial for the treatment of diabetic nephropathy. NOX-E36 is a Spiegelmer® that binds and neutralizes CCL2/MCP-1 (C-C Chemokine Ligand / Monocyte Chemoattractant Protein-1), a pro-inflammatory chemokine that plays an important role in the progression of diabetic nephropathy, the most common single cause of chronic kidney failure and end-stage renal disease.

25 Jul 2013

Study shows obese kidney failure patients derive survival advantage from transplantation

Most obese individuals with kidney failure can prolong their lives by receiving a kidney transplant, although this survival benefit is lower in severely obese individuals. That's the conclusion of a new study published in the American Journal of Transplantation.

25 Jul 2013

Randomized trial examines purging of tumor cells from stem cells prior to transplantation in neuroblastoma patients

Judith Villablanca, MD, of The Saban Research Institute of Children's Hospital Los Angeles, Susan Kreissman, MD, of Duke University Medical Center, and colleagues reported the results of a randomized, phase 3 clinical trial conducted by the Children's Oncology Group examining the effect of selectively removing (purging) tumor cells from blood stem cells before they are transplanted back into patients with high-risk neuroblastoma following high-dose chemotherapy.

25 Jul 2013

Report shows that fatal rabies virus is transmitted through transplanted kidney

An investigation into the source of a fatal case of raccoon rabies virus exposure indicates the individual received the virus via a kidney transplant 18 months earlier, findings suggesting that rabies transmitted by this route may have a long incubation period, and that although solid organ transplant transmission of infectious encephalitis is rare, further education to increase awareness is needed, according to a study in the July 24/31 issue of JAMA.

24 Jul 2013

Transplant News and Research

Research: Larger lungs are associated with increased chance of survival

Researchers reveal location of human blood stem cells that may improve bone marrow transplants

Viropharma announces financial results for second quarter of 2013

University of Iowa study links bigger lungs with improved survival for transplant patients

AstraZeneca, FibroGen partner to develop, commercialize anemia drug candidate FG-4592

Researchers study how human herpes virus packages genetic information during infection

Healthcare professionals are urged to counsel patients on healthy sex life after stroke

Interferon-free treatment for genotype-1b hepatitis C patients: an interview with Professor Wulf Boecher, Boehringer Ingelheim

Adolescent patients who received kidney transplant appear to be at increased risk for transplant failure

Hope for treatment of childhood infections may come straight from the gut: Therapeutic poop

NIH expands CRIC study to identify risk factors for progression of early stage CKD

FDA approves Rebiotix's IND application to begin RBX2660 Phase 2 study for recurrent CDI

Hepatitis C (HCV) testing for baby boomers: an interview with Dr. Donald Jensen, Director, Center for Liver Diseases, University of Chicago

Viewpoints: Doctors' sway over Medicare pay; hospital rankings not all they seem; legal immigrants' health needs overlooked

Weekend reading: The mystery of some innovations that are slow to be accepted; myths about the obesity crisis

Gout, uric acid levels and risk of death: an interview with Professor Austin Stack, Graduate Entry Medical School, University of Limerick

NOXXON completes patient recruitment of NOX-E36 Phase IIa trial for treatment of diabetic nephropathy

Study shows obese kidney failure patients derive survival advantage from transplantation

Randomized trial examines purging of tumor cells from stem cells prior to transplantation in neuroblastoma patients

Report shows that fatal rabies virus is transmitted through transplanted kidney

Leveraging the power of automation to boost research

Automating research - solutions and best practices

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