Blood Vessels News and Research

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Omeros reports additional positive data from OMS721 Phase 2 trial for treatment of thrombotic microangiopathies

Omeros Corporation today announced additional positive data in the company's Phase 2 clinical trial of OMS721 for the treatment of thrombotic microangiopathies (TMAs). TMAs are a family of rare, debilitating and life-threatening disorders characterized by excessive thrombi (clots) – aggregations of platelets – in the microcirculation of the body's organs, most commonly the kidney and brain.

18 Aug 2015

Researchers test new non-invasive technique that can accurately detect malignant melanoma

Researchers have developed a new non-invasive technique which can accurately detect malignant melanoma without a biopsy.

18 Aug 2015

Muscle mass appears to ward off bad cardiovascular effects of obesity

Even without losing fat, more muscle appears to go a long way in fighting off the bad cardiovascular effects of obesity. That emerging evidence has scientists looking hard for new targets to uncouple the unhealthy relationship between fat and cardiovascular disease.

18 Aug 2015

Regulation of tumor microenvironment may offer alternate method for cancer treatment

Scientists know that activation of growth factor receptors like epidermal growth factor receptors (EGFR) promote tumor progression in many types of cancer.

18 Aug 2015

Tracking retinal changes may help doctors to adjust schizophrenia treatment in the future

Schizophrenia is associated with structural and functional alterations of the visual system, including specific structural changes in the eye. Tracking such changes may provide new measures of risk for, and progression of the disease, according to a literature review published online in the journal Schizophrenia Research: Cognition, authored by researchers at New York Eye and Ear Infirmary of Mount Sinai and Rutgers University.

18 Aug 2015

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Children born with the major congenital heart defect hypoplastic left heart syndrome (HLHS) often must undergo a series of corrective surgeries beginning at birth. While most have the standard three-stage Norwood procedure, a hybrid strategy has been introduced to offset some disadvantages associated with the Norwood surgeries. In a report in The Journal of Thoracic and Cardiovascular Surgery, investigators compare whether outcomes can be improved if an arterial shunt is used as a source of pulmonary blood flow rather than the more conventional venous shunt as part of the hybrid strategy of HLHS surgical reconstruction.

14 Aug 2015

Combination of chemotherapy and immune-blocking drug could prevent cancer recurrence

Giving patients a drug that blocks part of the immune system from going into overdrive might help prevent cancer coming back in some people, according to research published today in Cancer Research.

13 Aug 2015

New study explains why statins are more beneficial than others in some cases

Statins' success in reducing atherosclerosis-related events has elevated the medications to wonder-drug status, with some researchers advocating for their wider use as a preemptive therapy for cardiovascular disease.

13 Aug 2015

McMaster University hematologist finds different limb loss syndromes

How people can develop limb gangrene and lose fingers and feet has baffled doctors for centuries. Now a McMaster University hematologist has identified different limb loss syndromes along with explanations for what is happening and what can be done about it.

13 Aug 2015

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

A review of 15 years’ worth of data in a national pediatric medical database has documented a substantial increase in the rate of hospitalizations for children with a form of high blood pressure once most common in those with congenital heart disease.

13 Aug 2015

Scientists identify molecular pathway that can contribute to vision loss in macular degeneration

Scientists have identified a pathway that leads to the formation of atypical blood vessels that can cause blindness in people with age-related macular degeneration.

12 Aug 2015

$Breakdown of fibrin protein essential for bone fracture repair$

Breakdown of fibrin protein essential for bone fracture repair

A team of Vanderbilt investigators has discovered that fibrin, a protein that was thought to play a key role in fracture healing, is not required. Instead, the breakdown of fibrin is essential for fracture repair.

12 Aug 2015

Researchers describe new Lab-on-a-Disc device for fast and reliable diagnostics of urinary tract infections

Urinary tract infections can quickly move from being a merely miserable experience to a life-threatening condition. Untreated cases may trigger sepsis, which occurs when the immune system, in an attempt to fight off the infection, inadvertently activates body-wide inflammation that can cause blood clots and leaky blood vessels.

12 Aug 2015

Scientists identify molecular partnership that may help explain how pancreatic cancer spreads

Scientists at the Johns Hopkins Kimmel Cancer Center have identified a molecular partnership in pancreatic cancer cells that might help to explain how the disease spreads — metastasizes — in some cases. Their findings reveal urgently needed new targets to treat pancreatic cancer, which strikes nearly 50,000 people in the U.S. each year and has only a 5 percent survival rate five years after diagnosis.

11 Aug 2015

EPFL scientists reveal that the brain is not as compact as we thought

Using an innovative method, EPFL scientists show that the brain is not as compact as we have thought all along. To study the fine structure of the brain, including its connections between neurons, the synapses, scientists must use electron microscopes. However, the tissue must first be fixed to prepare it for this high magnification imaging method.

11 Aug 2015

Sigma 1 receptor appears to play vital role in supporting the retina

A receptor that is already a target for treating neurodegenerative disease also appears to play a key role in supporting the retina, scientists report.

11 Aug 2015

Johns Hopkins researchers report on more effective way to spot patients at risk of septic shock

For a patient with sepsis - which kills more Americans every year than AIDS and breast and prostate cancer combined - hours can make the difference between life and death.

6 Aug 2015

Researchers find CD163 protein limits muscle repair after ischemic injury

Researchers have identified a protein produced by white blood cells that puts the brakes on muscle repair after injury. By removing the protein CD163 from mice, scientists at Emory University School of Medicine could boost muscle repair and recovery of blood flow after ischemic injury (damage caused by restriction of blood flow).

5 Aug 2015

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

Ethiopians have lived at high altitudes for thousands of years, providing a natural experiment for studying human adaptations to low oxygen, a condition known as hypoxia. One factor that may enable Ethiopians to tolerate high altitudes and hypoxia is the endothelin receptor type B (EDNRB) gene.

4 Aug 2015

BrightFocus announces recipients of 2015 research program grants

BrightFocus Foundation, which funds research worldwide on Alzheimer's disease, glaucoma, and macular degeneration, today announced that its 2015 research program grants have been awarded to 58 scientists in 20 states and 7 foreign countries. Part of an $11 million research investment, the grants reflect the largest annual research funding in the foundation's history.

4 Aug 2015

Blood Vessels News and Research

Omeros reports additional positive data from OMS721 Phase 2 trial for treatment of thrombotic microangiopathies

Researchers test new non-invasive technique that can accurately detect malignant melanoma

Muscle mass appears to ward off bad cardiovascular effects of obesity

Regulation of tumor microenvironment may offer alternate method for cancer treatment

Tracking retinal changes may help doctors to adjust schizophrenia treatment in the future

Arterial shunt in hybrid palliation better for hypoplastic left heart syndrome treatment

Combination of chemotherapy and immune-blocking drug could prevent cancer recurrence

New study explains why statins are more beneficial than others in some cases

McMaster University hematologist finds different limb loss syndromes

Johns Hopkins study finds substantial increase in rate, costs of hospitalizations for pediatric pulmonary hypertension

Scientists identify molecular pathway that can contribute to vision loss in macular degeneration

Breakdown of fibrin protein essential for bone fracture repair

Researchers describe new Lab-on-a-Disc device for fast and reliable diagnostics of urinary tract infections

Scientists identify molecular partnership that may help explain how pancreatic cancer spreads

EPFL scientists reveal that the brain is not as compact as we thought

Sigma 1 receptor appears to play vital role in supporting the retina

Johns Hopkins researchers report on more effective way to spot patients at risk of septic shock

Researchers find CD163 protein limits muscle repair after ischemic injury

Study provides mechanism for EDNRB gene's role in adaptation to life at high altitudes

BrightFocus announces recipients of 2015 research program grants

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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