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Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

The glymphatic system enables the flow of cerebrospinal fluid to the brain tissue, particularly during sleep, enabling the fluid to cleanse the tissue and carry accumulated metabolites with it towards the bloodstream during waking hours.

4 May 2022

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Weill Cornell Medicine researchers have identified a protein in Mycobacterium tuberculosis (Mtb) that contributes to drug tolerance, a phenomenon that allows bacteria to survive treatment with drugs that would normally kill them.

4 May 2022

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Researchers determined the threshold neutralizing antibody titer for effective COVID-19 convalescent plasma therapy.

4 May 2022

Effect of vegetarian food intake on nutritional status and growth of young children

In a new study, researchers examined the association between a vegetarian diet and growth, micronutrients, and lipids among healthy children.

4 May 2022

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

The current study aims to use sophisticated machine learning models that stratify patient data by age group to predict disease progression in almost 7,000 patients studied in community hospital settings.

4 May 2022

Researchers create models to study brain metastases that recapitulate the disease

The spreading of different types of cancer cells to the brain, forming brain metastases, is the main cause of morbidity and mortality associated to cancer. Now, a new study led by Cláudia C. Faria, principal investigator in the group of João Taborda Barata at the Instituto de Medicina Molecular João Lobo Antunes (iMM; Portugal) and neurosurgeon at the Hospital Santa Maria (HSM, CHULN, Portugal), and published today in the scientific journal Cell Reports Medicine* created a library of models to study brain metastases that recapitulate the disease in humans. These models can be a relevant tool to understand the disease and discover new therapeutical approaches tailormade to each patient.

4 May 2022

New drug combinations for obesity and diabetes may show greater efficacy than single therapy

Canadian and German researchers are teaming up to identify new drug combinations to treat people with obesity and Type 2 diabetes.

4 May 2022

Novel surface coating protects implants and medical devices from infections

Infections after hip replacements and from orthopaedic device procedures can be complicated and lead to painful and repeat surgeries, with the chance of ‘superbugs’ leading to fatality.

4 May 2022

How a COVID support team mitigated SARS-CoV-2 transmission within a university community

Researchers demonstrated how a campus coronavirus disease support team [CCST] efficiently mitigated potential COVID 2019 (COVID-19) outbreaks within the school of public health (SPH) of the mid-Atlantic university in the United States (US).

3 May 2022

Novel magnetic therapy complements chemotherapy to enhance breast cancer treatment outcomes

Breast cancer is the leading cause of cancer-associated death for women worldwide. While chemotherapy is the mainstream treatment for breast cancer, more than 50% of women undergoing chemotherapy will experience at least one chemotherapy-related adverse side effect.

3 May 2022

Exercise can have a beneficial effect on factors contributing to NAFLD, study shows

Exercise supports the treatment of non-alcoholic fatty liver disease by impacting on several metabolic pathways in the body, a new study from the University of Eastern Finland shows.

3 May 2022

Joint associations of genetic risk and diet quality with incident type 2 diabetes

Researchers assessed the impact of polygenic scores and diet quality on type 2 diabetes.

3 May 2022

EIS Conference highlights CDC’s disease detectives’ outbreak investigations, innovative analyses on public health

CDC will hold its annual Epidemic Intelligence Service Conference May 2-5, 2022, via a virtual platform that is free and open to the public.

3 May 2022

DeNovix receives customer service company of the year award

DeNovix Inc, a developer and manufacturer of instrumentation and assays for the life sciences, has been awarded the prestigious Customer Service Company of the Year at the SelectScience Scientists’ Choice Awards for Life Science.

From DeNovix Inc. 3 May 2022

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

A new study published in the journal Gastroenterology used upper and lower gastrointestinal endoscopy to assess whether gut antigen persistence leads to post-acute COVID-19 in patients with or without post-acute COVID-19 symptoms.

3 May 2022

Moms with limited financial resources experienced tremendous stress during the pandemic, finds study

A recent study from North Carolina State University finds that mothers with limited financial resources often experienced tremendous stress during the pandemic, but that they also valued the opportunity to spend more quality time with their children.

3 May 2022

One step solvothermal synthesis of pure red emissive carbon dots from citric acid and urea in formic acid

Carbon dots (CDs) are a kind of zero-dimensional carbonaceous nanomaterial. Due to their ultra-small size (usually less than 10 nm), simple synthesis, low toxicity, well-documented biocompatibility, and outstanding luminescent properties, CDs have attracted wild applications, particularly in bioimaging and biomedical fields.

3 May 2022

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

Glioma is an intracranial malignant tumor that still poses a major clinical challenge due to its highly invasive nature, low cure rate, and high mortality rate.

3 May 2022

New smartphone-powered microchip opens the door for faster, cheaper at-home medical testing

A University of Minnesota Twin Cities research team has developed a new microfluidic chip for diagnosing diseases that uses a minimal number of components and can be powered wirelessly by a smartphone. The innovation opens the door for faster and more affordable at-home medical testing.

3 May 2022

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

The pathogen Acinetobacter baumannii can survive on hospital surfaces -; without water -; for months, an ability that has helped it become a leading cause of hospital-acquired infections.

2 May 2022

Laboratory News and Research

Hypertonic saline solution enhances glymphatic spinal cord delivery of pharmaceutical agents

Study identifies a protein in Mycobacterium tuberculosis that contributes to drug tolerance

Phase 2 clinical trial of COVID-19 convalescent plasma with high antibody titers

Effect of vegetarian food intake on nutritional status and growth of young children

High-performing age-stratified machine-learning models for the prediction of the severity of COVID-19 progression

Researchers create models to study brain metastases that recapitulate the disease

New drug combinations for obesity and diabetes may show greater efficacy than single therapy

Novel surface coating protects implants and medical devices from infections

How a COVID support team mitigated SARS-CoV-2 transmission within a university community

Novel magnetic therapy complements chemotherapy to enhance breast cancer treatment outcomes

Exercise can have a beneficial effect on factors contributing to NAFLD, study shows

Joint associations of genetic risk and diet quality with incident type 2 diabetes

EIS Conference highlights CDC’s disease detectives’ outbreak investigations, innovative analyses on public health

DeNovix receives customer service company of the year award

Long COVID is characterized SARS-CoV-2 antigen persistence in the gut mucosa

Moms with limited financial resources experienced tremendous stress during the pandemic, finds study

One step solvothermal synthesis of pure red emissive carbon dots from citric acid and urea in formic acid

Multifunctional YHM shows promise for diagnosis and treatment of orthotopic glioma

New smartphone-powered microchip opens the door for faster, cheaper at-home medical testing

Researchers discover how Acinetobacter baumannii can survive on hospital surfaces without water

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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