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Survival rates increased among patients who received blood stem cell transplants: Study

Survival rates have increased significantly among patients who received blood stem cell transplants from both related and unrelated donors, according to a study published in the Journal of Clinical Oncology today.

29 May 2013

Transplantation of human stem cells improves muscle function in rats used to model ALS

Transplantation of human stem cells in an experiment conducted at the University of Wisconsin-Madison improved survival and muscle function in rats used to model ALS, a nerve disease that destroys nerve control of muscles, causing death by respiratory failure.

29 May 2013

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Johns Hopkins scientists report that a 10-minute test for "frailty" first designed to predict whether the elderly can withstand surgery and other physical stress could be useful in assessing the increased risk of death and frequent hospitalization among kidney dialysis patients of any age.

29 May 2013

Lab-based skin test eliminates risk of adverse reactions to new drugs, cosmetics

A simple lab-based skin test which eliminates the risk of adverse reactions to new drugs, cosmetics and household chemicals has been developed by a Newcastle University, UK team.

28 May 2013

Nephrologists rarely discuss estimates of life-expectancy with patients, study finds

Seriously ill patients undergoing hemodialysis are more optimistic about their prognosis and prospects for transplants than their nephrologists, according to a study published online by JAMA Internal Medicine.

28 May 2013

Improved communication could help with end of life decision making, suggests BIDMC research

In any given year, 400,000 Americans suffering from end-stage kidney disease will undergo dialysis, and as many as 20 to 25 percent of those dialysis patients will die, a statistic comparable to many types of cancer.

28 May 2013

Research report examines trends in pediatric organ donation and transplantation

Changes in the circumstances of when organs are donated to pediatric patients has resulted in a decreased number of organ transplant wait-list deaths over the past decade, according to research published online this week in the journal Pediatrics.

24 May 2013

OPKO reports more than 50% enrollment in phase 3 trial of Rayaldy for treatment of secondary hyperparathyroidism

OPKO Health, Inc., has surpassed 50% enrollment in the first phase 3 trial of RayaldyTM to treat patients with secondary hyperparathyroidism (SHPT), stage 3 or 4 chronic kidney disease (CKD) and vitamin D insufficiency.

24 May 2013

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Treating pediatric leukemia patients with a liposomal formulation of anthracycline-based chemotherapy at a more intense-than-standard dose during initial treatment may result in high survival rates without causing any added heart toxicity, according to the results of a study published online today in Blood, the Journal of the American Society of Hematology.

24 May 2013

Takeda begins MLN9708 phase 3 clinical trial in newly diagnosed myeloma patients

Takeda Pharmaceutical Company Limited today announced the initiation of an international phase 3 clinical trial evaluating once a week MLN9708 in combination with lenalidomide and dexamethasone in patients with newly diagnosed multiple myeloma who are not candidates for transplant.

24 May 2013

Findings suggest that a prosaposin-based drug could block metastasis spread

By studying the roles two proteins, thrombospondin-1 and prosaposin, play in discouraging cancer metastasis, a trans-Atlantic research team has identified a five-amino acid fragment of prosaposin that significantly reduces metastatic spread in mouse models of prostate, breast and lung cancer.

22 May 2013

Kidneys discarded for transplant can be used for manufacturing replacement organs, say researchers

Nearly 20 percent of kidneys that are recovered from deceased donors in the U.S. are refused for transplant due to factors ranging from scarring in small blood vessels of the kidney's filtering units to the organ going too long without blood or oxygen. But, what if instead of being discarded, these organs could be "recycled" to help solve the critical shortage of donor organs?

21 May 2013

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

AbbVie announced today the initiation of a Phase 3 clinical study called SONAR (Study Of Diabetic Nephropathy with Atrasentan) to assess the effects of the investigational compound atrasentan - when added to standard of care - on progression of kidney disease in patients with stage 2 to 4 chronic kidney disease and type 2 diabetes.

21 May 2013

Cell Therapeutics announces issuance of final benefit assessment report for PIXUVRI

Cell Therapeutics, Inc. today reported that Germany's Federal Joint Committee has issued its final benefit assessment report for PIXUVRI (pixantrone), which is indicated as a monotherapy for the treatment of adult patients with aggressive B-cell non-Hodgkin lymphoma (NHL) who have failed two or three prior lines of therapy.

20 May 2013

Researchers link coffee consumption with reduced risk of primary sclerosing cholangitis

Research presented today at Digestive Disease Week explores new discoveries in liver disease research, with findings about the impact of coffee on autoimmune disease and palliative care for cirrhotic patients.

20 May 2013

Diaverum to present results of latest research work at ERA/EDTA 2013

Diaverum, one of the world's leading renal care service providers, is presenting its service portfolio and the results of its latest research at the ERA/EDTA 2013.

17 May 2013

Viewpoints: When a doctor should keep quiet; 2 views of hospital pricing; Stem cell 'snake oil'

In medical school, we were taught not to withhold information from our patients or to be "paternal" in making decisions for them. We internalized the idea that fully informed patients are better equipped to make treatment decisions.

17 May 2013

Robotic transplantation may reduce health disparities for obese patients with chronic kidney failure

Obese patients who received robotic kidney transplants had fewer wound complications than patients who received traditional "open" transplant surgery, according to surgeons at the University of Illinois Hospital & Health Sciences System.

17 May 2013

Study suggests need for better anti-rejection therapies

Transplant researchers at the University of Pittsburgh School of Medicine challenge a long-held assumption about how biologic pathways trigger immune system rejection of donor organs in a report published online today in the Journal of Clinical Investigation.

16 May 2013

Research breakthrough: Human skin cells becomes embryonic stem cells

Scientists at Oregon Health & Science University and the Oregon National Primate Research Center have successfully reprogrammed human skin cells to become embryonic stem cells capable of transforming into any other cell type in the body.

16 May 2013

Transplant News and Research

Survival rates increased among patients who received blood stem cell transplants: Study

Transplantation of human stem cells improves muscle function in rats used to model ALS

New test to predict increased risk of death, hospitalization among kidney dialysis patients

Lab-based skin test eliminates risk of adverse reactions to new drugs, cosmetics

Nephrologists rarely discuss estimates of life-expectancy with patients, study finds

Improved communication could help with end of life decision making, suggests BIDMC research

Research report examines trends in pediatric organ donation and transplantation

OPKO reports more than 50% enrollment in phase 3 trial of Rayaldy for treatment of secondary hyperparathyroidism

Liposomal anthracycline-based chemotherapy effective for children with leukemia: Study

Takeda begins MLN9708 phase 3 clinical trial in newly diagnosed myeloma patients

Findings suggest that a prosaposin-based drug could block metastasis spread

Kidneys discarded for transplant can be used for manufacturing replacement organs, say researchers

AbbVie starts Phase 3 clinical study of atrasentan in patients with diabetic nephropathy

Cell Therapeutics announces issuance of final benefit assessment report for PIXUVRI

Researchers link coffee consumption with reduced risk of primary sclerosing cholangitis

Diaverum to present results of latest research work at ERA/EDTA 2013

Viewpoints: When a doctor should keep quiet; 2 views of hospital pricing; Stem cell 'snake oil'

Robotic transplantation may reduce health disparities for obese patients with chronic kidney failure

Study suggests need for better anti-rejection therapies

Research breakthrough: Human skin cells becomes embryonic stem cells

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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