Blood Vessels News and Research

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EMA grants Orphan Drug Designation to Stempeucel for treatment of Thromboangiitis Obliterans

Stempeutics Research, a group company of Manipal Education & Medical Group and a joint venture with Cipla Group, announced today that the European Medicines Agency (EMA) has granted Orphan Drug Designation for its drug Stempeucel® for the treatment of Thromboangiitis Obliterans.

2 Jun 2015

Trabectedin may be better than dacarbazine for treatment of soft tissue sarcoma

Janssen Research & Development, LLC announced data from the Phase 3 multicenter study SAR3007, which demonstrated a significant improvement in progression-free survival with trabectedin (YONDELIS®) compared to dacarbazine in patients with advanced liposarcoma (LPS) or leiomyosarcoma (LMS) previously treated with an anthracycline and at least one additional chemotherapy regimen.

2 Jun 2015

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

CQDM, Brain Canada and the Ontario Brain Institute award close to $8.5M to six (6) multi-disciplinary and multi-provincial research teams across Canada to address unmet needs in neuroscience within their Focus on Brain strategic initiative. To this amount, $1.5M is added from the various research entities involved as in-kind contributions.

27 May 2015

Understanding the antimicrobial action of borrelidin: an interview with Dr Min Guo, TSRI

Borrelidin is a naturally occurring antibiotic isolated from the Streptomyces species and initially from Streptomyces rochei in 1949. It is called Borrelidin because it was firstly discovered as having anti-Borrelia activity. Borrelia is a type of bacteria...

27 May 2015

Tiny drug-delivery system can help identify brain tumor types through 'virtual biopsies'

Biomedical researchers at Cedars-Sinai have invented a tiny drug-delivery system that can identify cancer cell types in the brain through "virtual biopsies" and then attack the molecular structure of the disease.

27 May 2015

Study could offer new way to treat, prevent diabetes-associated blindness

Reporting on their study with lab-grown human cells, researchers at The Johns Hopkins University and the University of Maryland say that blocking a second blood vessel growth protein, along with one that is already well-known, could offer a new way to treat and prevent a blinding eye disease caused by diabetes.

26 May 2015

Researchers map out surgical anatomy, approaches for auditory brainstem implant placement

A technique called auditory brainstem implantation can restore hearing for patients who can't benefit from cochlear implants. A team of US and Japanese experts has mapped out the surgical anatomy and approaches for auditory brainstem implantation in the June issue of Operative Neurosurgery, published on behalf of the Congress of Neurological Surgeons by Wolters Kluwer.

22 May 2015

Scientists reveal how lymphatic system develops in embryo

For over one hundred years, scientists have debated the question of the origins of the lymphatic system - a parallel system to the blood vessels that serves as a conduit for everything from immune cells to fat molecules to cancer cells. This issue has now been resolved by Dr. Karina Yaniv of Weizmann Institute's Biological Regulation Department. In a study reported online today in Nature, she and her team revealed how the lymphatic system develops in the embryo and for the first time managed to grow lymphatic cells in the lab.

21 May 2015

Stereotactic body radiotherapy appears to be safe, effective for some pancreatic cancer patients

Two studies from Johns Hopkins Kimmel Cancer Center researchers add to preliminary evidence that high-dose radiation treatment, called stereotactic body radiotherapy, appears to be safe and as effective as standard radiation treatment for certain patients with pancreatic cancer whose tumors are advanced but have not spread.

20 May 2015

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Current users of menopausal hormone therapy (MHT) are more than twice as likely than non-users to develop lower gastrointestinal bleeding and ischemic colitis, especially if they use the therapy for longer durations, according to a study at Digestive Disease Week 2015.

19 May 2015

Research leads way for noninvasive detection of early stage liver cancer

Led by Georgia State University, researchers have developed the first robust and noninvasive detection of early stage liver cancer and liver metastases, in addition to other liver diseases, such as cirrhosis and liver fibrosis.

15 May 2015

Long, non-coding RNAs play a role in heart attacks, strokes and cancer

About 70 percent of our genes provide the blueprint for biomolecules whose function is only now being discovered - non-coding RNAs. Instead of being translated into proteins, they seem to perform steering functions in the body.

14 May 2015

Growth of neuronal and vascular networks is controlled by same signaling molecules

Neurons and blood vessels often traverse the body side by side, a fact observed as early as the 16th century by the Flemish anatomist Andreas Vesalius. Only over the last ten years, however, researchers have discovered that the growth of neuronal and vascular networks is controlled by the same molecules.

14 May 2015

MRI screening helps in accurate and rapid stroke treatment

Time is critical when it comes to stroke, and early treatment is associated with better outcomes. According to the Screening with MRI for Accurate and Rapid stroke Treatment (SMART) study, small changes in quality improvement procedures enabled clinicians to use MRI scans to diagnose stroke patients before giving acute treatment, within 60 minutes of hospital arrival.

14 May 2015

New study reveals genetic causes of rare syndrome that manifests as high blood pressure

The culmination of two decades of research, a new study reveals the genetic causes of a curious, rare syndrome that manifests as hypertension (high blood pressure) accompanied by short fingers (brachydactyly type E).

12 May 2015

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Increased vascular stiffness has been identified as an important part of hypertension in aging adults. Previous studies of aortic stiffness have focused on changes in structural proteins that alter the properties of vascular walls causing them to become rigid.

11 May 2015

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Individuals with this altered gene have hereditary hypertension (high blood pressure) and at the same time a skeletal malformation called brachydactyly type E, which is characterized by unusually short fingers and toes. The effect on blood pressure is so serious that -- if left untreated -- it most often leads to death before age fifty.

11 May 2015

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

Lupus is a chronic, autoimmune disease, with many different symptoms so it is hard to diagnose. It affects each person differently and it has an unpredictable disease course with flare ups and quiet time. Some patients describe lupus as if they are riding a roller coaster with blinders on because they cannot always tell when they will feel well or sick...

11 May 2015

Comprehensive stroke centers reduce mortality risk in patients treated for hemorrhagic stroke

New research published today in the Journal of the American Heart Association indicates that patients who are treated for hemorrhagic stroke at a comprehensive stroke center are more likely to receive specialized treatment, reducing the risk of mortality.

7 May 2015

Preterm babies treated with bevacizumab for severe retinopathy of prematurity have lower motor scores

Preterm babies with retinopathy of prematurity (ROP) treated using bevacizumab, a growth inhibitor, have been found to have lower motor scores than babies treated with traditional laser ablation. The research is being presented at the 2015 Annual Meeting of the Association for Research in Vision and Ophthalmology this week in Denver, Colo.

7 May 2015

Blood Vessels News and Research

EMA grants Orphan Drug Designation to Stempeucel for treatment of Thromboangiitis Obliterans

Trabectedin may be better than dacarbazine for treatment of soft tissue sarcoma

Six research teams awarded grant to accelerate discovery of new drugs for brain, nervous system disorders

Understanding the antimicrobial action of borrelidin: an interview with Dr Min Guo, TSRI

Tiny drug-delivery system can help identify brain tumor types through 'virtual biopsies'

Study could offer new way to treat, prevent diabetes-associated blindness

Researchers map out surgical anatomy, approaches for auditory brainstem implant placement

Scientists reveal how lymphatic system develops in embryo

Stereotactic body radiotherapy appears to be safe, effective for some pancreatic cancer patients

Current menopausal hormone therapy users at increased risk of experiencing GI bleeding

Research leads way for noninvasive detection of early stage liver cancer

Long, non-coding RNAs play a role in heart attacks, strokes and cancer

Growth of neuronal and vascular networks is controlled by same signaling molecules

MRI screening helps in accurate and rapid stroke treatment

New study reveals genetic causes of rare syndrome that manifests as high blood pressure

Scientists find smooth muscle cells as major contributing factor to vascular stiffness

Scientists identify gene that causes hereditary hypertension and brachydactyly type E

Raising lupus awareness: an interview with Professor Ramsey-Goldman, MD

Comprehensive stroke centers reduce mortality risk in patients treated for hemorrhagic stroke

Preterm babies treated with bevacizumab for severe retinopathy of prematurity have lower motor scores

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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