Blood Vessels News and Research

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New study identifies genetic factors for rosacea

Today marked the publication of the first ever genome-wide association study of rosacea, a common and incurable skin disorder. Led by Dr. Anne Lynn S. Chang of Stanford University's School of Medicine, and co-authored by 23andMe, the study is the first to identify genetic factors for this condition.

11 Mar 2015

Imperial scientists develop new test that uses human stem cells to predict side effects of drugs

Scientists at Imperial College London have developed a test that uses combinations of cells from a single donor's blood to predict whether a new drug will cause a severe immune reaction in humans.

10 Mar 2015

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

For the first time, CRISPR-Cas9 gene-editing technology has been employed in a whole organism model to systematically target every gene in the genome.

6 Mar 2015

Non-viral gene therapy provides relief for diabetics with constant foot pain

Walking barefoot on sand "felt like walking on glass" for Keith Wenckowski, who has lived with type-one diabetes for more than two decades.

6 Mar 2015

New research challenges current theories of ageing

Older brains may be more similar to younger brains than previously thought.

5 Mar 2015

Duke researchers find major shift in treatments for peripheral artery disease

Federal efforts to curb Medicare costs for unclogging blood vessels in the limbs slowed the growing use of the treatments, but also coincided with a marked increase in doctors using a more expensive approach, according to an analysis by Duke Medicine researchers.

5 Mar 2015

Common flame retardants linked to obesity, say UH researchers

Could your electronics be making you fat? According to University of Houston researchers, a common flame retardant used to keep electronics from overheating may be to blame.

5 Mar 2015

Breakthrough treatment option for men with benign prostatic hyperplasia

Men with benign prostatic hyperplasia (BPH), a condition in which the prostate is enlarged but not cancerous, have a new, breakthrough treatment option that is less invasive and has fewer complications than other minimally invasive treatments, such as transurethral resection of the prostate and surgical options, according to research presented at the Society of Interventional Radiology's Annual Scientific Meeting.

3 Mar 2015

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.

2 Mar 2015

New algorithm can gauge long-term death risk based on treadmill exercise performance

Analyzing data from 58,000 heart stress tests, Johns Hopkins cardiologists report they have developed a formula that estimates one's risk of dying over a decade based on a person's ability to exercise on a treadmill at an increasing speed and incline.

2 Mar 2015

Young women veterans referred for cardiac tests more likely to be depressed than men veterans

Women veterans who had specialized heart tests were younger and more likely to be obese, depressed and suffer from post-traumatic stress disorder than men veterans, according to a study published in an American Heart Association journal.

27 Feb 2015

Researchers report that 15% of pancreatic cancer patients may benefit from personalized therapies

Cancer researchers at Indiana University report that about 15 percent of people with pancreatic cancer may benefit from therapy targeting a newly identified gene signature.

27 Feb 2015

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Digital ulcers (DUs) are a frequent, painful, and quality of life altering complication for patients with systemic sclerosis (SSc), a connective tissue disease causing a progressive loss of small blood vessels and resulting changes in organs and tissues. DUs on the fingertips of SSc patients are slow to heal, if they heal at all, as many are unresponsive to any therapies.

26 Feb 2015

Researchers generate mature, functional skeletal muscles using new approach

A team of researchers from Italy, Israel and the United Kingdom has succeeded in generating mature, functional skeletal muscles in mice using a new approach for tissue engineering. The scientists grew a leg muscle starting from engineered cells cultured in a dish to produce a graft.

25 Feb 2015

Sorafenib, sunitinib provide no benefit to patients with locally advanced kidney cancer

Findings from a federally funded study suggest that patients with locally advanced kidney cancer should not be treated with either adjuvant (post-surgery) sorafenib or sunitinib. The average period to disease recurrence was similar between those who received sorafenib or sunitinib after surgery (5.6 years) and those treated with placebo (5.7 years).

25 Feb 2015

Scientists detect new molecule that contributes to development of liver fibrosis

Liver fibrosis, which is the progressive formation of scar tissue in the liver, is a massive medical problem. An estimated ten percent of the population is affected by liver fibrosis or its corresponding later stage, liver cirrhosis. A variety of causes can lead to liver fibrosis, the most widely recognized ones being alcohol consumption and virus-induced chronic liver inflammation.

25 Feb 2015

Investigators define prevalence, associated factors for vasospasm in children with brain injuries

Vasospasm, or severe narrowing of blood vessels, is a dangerous complication observed in children with moderate to severe traumatic brain injury. In a paper recently published in Critical Care Medicine, investigators at Nationwide Children's Hospital have further defined the prevalence, associated factors and time course for vasospasm in children with these brain injuries.

25 Feb 2015

Two widely used targeted therapy drugs not effective in preventing return of kidney cancer

Two widely used targeted therapy drugs— approved by the FDA for use in metastatic kidney cancer —are no more effective than a placebo in preventing return of the disease to increase life spans of patients suffering from advanced kidney cancer after surgery, according to new results to be presented by a researcher at the University of Pennsylvania's Abramson Cancer Center during the 2015 Genitourinary Cancers Symposium.

24 Feb 2015

Researchers find key protein critical to the success of common anti-platelet drug Plavix

Researchers at the UNC School of Medicine have found that the blood platelet protein Rasa3 is critical to the success of the common anti-platelet drug Plavix, which breaks up blood clots during heart attacks and other arterial diseases.

24 Feb 2015

Johns Hopkins researcher helps discover effectiveness of three drugs for treating patients with DME

A researcher from Johns Hopkins Medicine helped lead colleagues from across the country in a government-sponsored study by the Diabetic Retinopathy Clinical Research Network to discover that three drugs -- Eylea, Avastin and Lucentis -- used to treat diabetic macular edema are all effective. They also discovered that Eylea outperformed the other two drugs when vision loss was moderate to severe.

23 Feb 2015

Blood Vessels News and Research

New study identifies genetic factors for rosacea

Imperial scientists develop new test that uses human stem cells to predict side effects of drugs

CRISPR-Cas9 gene-editing technology targets every gene in the genome in animal cancer model

Non-viral gene therapy provides relief for diabetics with constant foot pain

New research challenges current theories of ageing

Duke researchers find major shift in treatments for peripheral artery disease

Common flame retardants linked to obesity, say UH researchers

Breakthrough treatment option for men with benign prostatic hyperplasia

U-M researchers reveal key role of two enzymes that help the body to remove cholesterol, other lipids

New algorithm can gauge long-term death risk based on treadmill exercise performance

Young women veterans referred for cardiac tests more likely to be depressed than men veterans

Researchers report that 15% of pancreatic cancer patients may benefit from personalized therapies

Fat cell transplantation benefits systemic sclerosis patients with non-healing digital ulcers

Researchers generate mature, functional skeletal muscles using new approach

Sorafenib, sunitinib provide no benefit to patients with locally advanced kidney cancer

Scientists detect new molecule that contributes to development of liver fibrosis

Investigators define prevalence, associated factors for vasospasm in children with brain injuries

Two widely used targeted therapy drugs not effective in preventing return of kidney cancer

Researchers find key protein critical to the success of common anti-platelet drug Plavix

Johns Hopkins researcher helps discover effectiveness of three drugs for treating patients with DME

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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