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Oral version of remdesivir could extend its reach and benefits to COVID-19 patients

Scientists at the University of North Carolina at Chapel Hill are testing a new route for remdesivir, a pill form of the COVID-19 treatment that’s given to half of all hospitalized patients with the disease.

22 Mar 2022

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

The loss of muscle mass and strength during aging is called sarcopenia. Affecting the elderly population, sarcopenia is a degenerative process that brings about a decrease in wellbeing and increased dependency.

22 Mar 2022

Fermented soybean waste could help mitigate effects of diet-induced obesity

An international team of scientists from Nanyang Technological University, Singapore (NTU Singapore) and Waseda University in Japan have found that fermented soybean waste, or okara, could improve fat metabolism and mitigate effects of diet-induced obesity.

22 Mar 2022

Research reveals significant decrease in gastrointestinal infections during first 6 months of the pandemic

The number of reported gastrointestinal infection outbreaks more than halved during the first 6 months of the COVID-19 pandemic in the UK, compared with the previous 5-year average, while lab confirmed cases fell by a third, finds research published in the open access journal BMJ Open.

22 Mar 2022

How valid are the reported results on health outcomes in children after acute SARS-CoV-2 infection?

Researchers discussed the validity of reported health outcomes post-acute infection with SARS-CoV-2 in children.

22 Mar 2022

Key mechanism that increases drug tolerance among microbial communities revealed

Research from the Francis Crick Institute has revealed a key mechanism which increases tolerance to drugs amongst microbial communities.

22 Mar 2022

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

The findings of a new study suggest that a ketogenic diet -; which is low in carbohydrates and protein, but high in fat -; helps to kill pancreatic cancer cells when combined with a triple-drug therapy developed by the Translational Genomics Research Institute (TGen), an affiliate of City of Hope.

22 Mar 2022

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

The National Institutes of Health is awarding a $3.8 million grant to John Rossmeisl, the Dr. and Mrs. Dorsey Taylor Mahin Professor of Neurology and Neurosurgery at the Virginia-Maryland College of Veterinary Medicine, and Waldemar Debinski, cancer biology professor at the Wake Forest School of Medicine.

21 Mar 2022

Research reveals enzyme-driven process that activates anti-cancer molecule

Years of toil in the laboratory have revealed how a marine bacterium makes a potent anti-cancer molecule.

21 Mar 2022

New computational approach creates spatial maps of single-cell data within tissues

A new computational approach developed by researchers at The University of Texas MD Anderson Cancer Center successfully combines data from parallel gene-expression profiling methods to create spatial maps of a given tissue at single-cell resolution.

21 Mar 2022

Saliva tests detect SARS-CoV-2 virus more quickly than nasal swabs

Genetic testing of saliva samples identifies the SARS-CoV-2 virus more quickly than testing of nasal swabs. The research is published March 21 in Microbiology Spectrum, a journal of the American Society for Microbiology.

21 Mar 2022

20% of childhood AML cases associated with rare genetic changes inherited through family bloodlines

It's a diagnosis you never want to hear: Acute Myeloid Leukemia (AML). These three words represent a devastating diagnosis of childhood cancer with dire consequences for many families.

21 Mar 2022

Mount Sinai Health System launches new Alopecia Areata Center of Excellence

In an unparalleled effort to deliver outstanding comprehensive care and to employ revolutionary approaches to novel therapeutics around the skin condition alopecia areata, the Mount Sinai Health System has launched the Alopecia Areata Center of Excellence.

21 Mar 2022

SEQENS makes multi-million-dollar investment in U.S. R&D laboratory

SEQENS, an integrated leader in the manufacturing of active ingredients and pharmaceutical intermediates, announced a multi-million-dollar investment in its research and development laboratory located in Devens, Mass.

From SEQENS 21 Mar 2022

Sectra signs digital pathology contract with Erasmus MC

International medical imaging IT and cybersecurity company Sectra has signed a digital pathology contract with Erasmus University Medical Center (Erasmus MC) in the Netherlands.

21 Mar 2022

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

A team of scientists from Turkey has recently evaluated the diversity and composition of gut microbiota in children diagnosed with multisystem inflammatory syndrome (MIS-C) and acute coronavirus disease 2019 (COVID-19). They have observed significant alteration in the gut microbiota composition in children with MIS-C. These changes are associated with autoimmunity, metabolic dysfunction, and obesity.

21 Mar 2022

Response to COVID-19 boosters in seronegative multiple sclerosis patients

Researchers report humoral T-cell responses in seronegative MS patients after receiving a third COVID-19 booster vaccine dose.

20 Mar 2022

Sinovac COVID vaccine shows modest efficacy against SARS-CoV-2 infection in children 3 to 5 years

Researchers investigate the efficacy of CoronaVac, COVID-19 vaccine developed by Sinovac Biotech, in children aged three to five years.

20 Mar 2022

Higher doses of antibiotics are needed to eliminate infection in a polymicrobial environment

A study has found that much higher doses of antibiotics are needed to eliminate a bacterial infection of the airways when other microbes are present.

19 Mar 2022

New method for generating lung tissue from just a few body cells in the lab

Laboratory studies of lung tissue usually require the removal of large amounts of human or animal tissue. Now scientists from the University of Freiburg's Faculty of Medicine have succeeded in collaboration with American researchers in generating tiny quantities of lung tissue, so-called organoids, from just a few body cells in the lab.

18 Mar 2022

Laboratory News and Research

Oral version of remdesivir could extend its reach and benefits to COVID-19 patients

Accumulation of damaged mitochondria triggers inflammatory processes that cause muscle atrophy

Fermented soybean waste could help mitigate effects of diet-induced obesity

Research reveals significant decrease in gastrointestinal infections during first 6 months of the pandemic

How valid are the reported results on health outcomes in children after acute SARS-CoV-2 infection?

Key mechanism that increases drug tolerance among microbial communities revealed

Study: Ketogenic diet helps kill pancreatic cancer cells when combined with a triple-drug therapy

Researchers win NIH grant to treat human brain cancer with a drug previously used on canines

Research reveals enzyme-driven process that activates anti-cancer molecule

New computational approach creates spatial maps of single-cell data within tissues

Saliva tests detect SARS-CoV-2 virus more quickly than nasal swabs

20% of childhood AML cases associated with rare genetic changes inherited through family bloodlines

Mount Sinai Health System launches new Alopecia Areata Center of Excellence

SEQENS makes multi-million-dollar investment in U.S. R&D laboratory

Sectra signs digital pathology contract with Erasmus MC

Substantial alteration in gut microbiome observed in children with with MIS-C and COVID

Response to COVID-19 boosters in seronegative multiple sclerosis patients

Sinovac COVID vaccine shows modest efficacy against SARS-CoV-2 infection in children 3 to 5 years

Higher doses of antibiotics are needed to eliminate infection in a polymicrobial environment

New method for generating lung tissue from just a few body cells in the lab

Lab Diagnostics and Automation - Second Edition eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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