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DNA, or deoxyribonucleic acid, is the hereditary material in humans and almost all other organisms. Nearly every cell in a person’s body has the same DNA. Most DNA is located in the cell nucleus (where it is called nuclear DNA), but a small amount of DNA can also be found in the mitochondria (where it is called mitochondrial DNA or mtDNA).

Could CRISPR be used as a SARS-CoV-2 antiviral?

The potential of using this gene manipulation technology as a SARS-CoV-2 inhibitor or prophylactic is investigated in a review recently uploaded to the journal Experimental Biology and Medicine (April 25th, 2021) by Arnab Banerjee and colleagues.

2 May 2021

Correcting mutations in muscle stem cells using new gene-editing technology

A new gene-editing technique can be used to correct mutations in muscle stem cells, paving the way for the first potential cell therapy for genetic muscle disorders.

30 Apr 2021

UTHSC professor receives $2.87 million to study genetic alterations associated with Gulf War illness

The National Institute of Environmental Health Sciences has awarded Byron C. Jones, PhD, professor in the Department of Genetics, Genomics, and Informatics at the University of Tennessee Health Science Center, $2.87 million for his continuing study of genetic alterations associated with Gulf War illness among former military personnel.

30 Apr 2021

Researchers identify important factor in the development of dendritic cells

The human immune system comprises functionally specialized cellular defense mechanisms that protect the body against disease. These include the dendritic cells.

30 Apr 2021

Cell-free DNA tests can reduce the need for biopsies to detect rejection after heart transplant

A new study, presented today at the AATS 101st Annual Meeting, shows that non-invasive cell-free DNA tests can reduce the need for regular surveillance biopsies to detect early rejection in heart transplant patients. The study was the first of its kind to be performed on both adult and pediatric patients.

30 Apr 2021

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

In a new resource for the scientific community, published today in Nature Biotechnology, researchers in the lab of Neville Sanjana, PhD, at the New York Genome Center (NYGC) and New York University (NYU) developed CRISPR-sciATAC, a novel integrative genetic screening platform that jointly captures CRISPR gene perturbations and single-cell chromatin accessibility genome-wide.

30 Apr 2021

Study evaluates first tumor-uninformed ctDNA assay to detect residual cancer cells after treatment

After patients with cancer undergo surgery to remove a tumor and sometimes additional chemotherapy, tools are used to identify patients at highest risk of recurrence.

30 Apr 2021

Geisinger wins $3.6 million contract to study the role of genetic variation in cancer

The National Cancer Institute (NCI), part of the National Institutes of Health, has awarded a 5-year, $3.6 million contract to Geisinger to study the role of genetic variation in cancer.

29 Apr 2021

A new strain of common probiotic can potentially be more effective at protecting infant health

Researchers at the University of Helsinki have created a strain of the Lacticaseibacillus rhamnosus GG probiotic that is able to utilize both lactose and casein as well as reproduce in dairy products.

29 Apr 2021

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Researchers at University of California San Diego School of Medicine have discovered one way in which SARS-CoV-2, the coronavirus that causes COVID-19, hijacks human cell machinery to blunt the immune response, allowing it to establish infection, replicate and cause disease.

29 Apr 2021

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

The flightless kakapo of New Zealand is in trouble. The world's heaviest parrot--representing one of the most ancestral branches of the parrot family tree--is nearly extinct, with barely 200 adults plodding the underbrush of four small islands.

29 Apr 2021

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

A protein variant common in malignant bladder tumor cells may serve as a new avenue for treating bladder cancer.

29 Apr 2021

Novel platform has potential to detect many disease-related biomarkers in just one test

Most conventional molecular diagnostics usually detect only a single disease-related biomarker. Great examples are the PCR tests currently used to diagnose COVID-19 by detecting a specific sequence from SARS-CoV-2.

28 Apr 2021

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

Scientific studies rarely focus on long non-coding RNA molecules (lncRNAs), even though they potentially regulate several diseases. The role of several lncRNAs in anti-viral inflammatory response regulation has recently been reported.

28 Apr 2021

A new concept for quickly detecting the presence of viruses

A Lancaster University professor has introduced a new concept for rapidly analysing for the presence of a virus from colds to coronaviruses.

26 Apr 2021

Researchers investigate how oxygen radicals protect against cancer

Originally, oxygen radicals - reactive oxygen species, or ROS for short - were considered to be exclusively harmful in the body.

26 Apr 2021

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

Lung cancer is a major global cause of mortality, reportedly accounting for 1.7 million deaths each year. The most common form of lung cancer is non-small-cell lung cancer (NSCLC), and early-stage NSCLCs can often be surgically resected.

26 Apr 2021

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

In their review paper recently published in the Indian Journal of Clinical Biochemistry, a group of authors discusses currently available and forthcoming CRISPR-based diagnostic assays, as well as the possibility of using the CRISPR/Cas system as a salient treatment or prevention strategy in the fight against coronavirus disease 2019 (COVID-19).

25 Apr 2021

A detailed look at two cases of symptomatic COVID in vaccinated individuals

In a recent brief report published in the prestigious New England Journal of Medicine, researchers from the Rockefeller University in New York described a case of two fully vaccinated individuals in whom they found subsequent breakthrough infections with variants of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), carrying a number of substitutions of interest.

25 Apr 2021

Researchers create a cell library to study how various sugars bind to and interact with receptors

Most infectious bacteria and viruses bind to sugars on the surface of our cells. Now researchers from the University of Copenhagen have created a library of tens of thousands of natural cells containing all the sugars found on the surface of our cells.

23 Apr 2021

DNA News and Research

Further Reading

Could CRISPR be used as a SARS-CoV-2 antiviral?

Correcting mutations in muscle stem cells using new gene-editing technology

UTHSC professor receives $2.87 million to study genetic alterations associated with Gulf War illness

Researchers identify important factor in the development of dendritic cells

Cell-free DNA tests can reduce the need for biopsies to detect rejection after heart transplant

Novel integrative genetic screening platform offers insights into role of DNA accessibility in cancer

Study evaluates first tumor-uninformed ctDNA assay to detect residual cancer cells after treatment

Geisinger wins $3.6 million contract to study the role of genetic variation in cancer

A new strain of common probiotic can potentially be more effective at protecting infant health

Researchers discover how SARS-CoV-2 hijacks human cell machinery to blunt immune response

Researchers apply 'kitchen sink approach' to produce 16 high-quality reference genomes

Male bladder cancer vulnerability could be exploited to design new therapeutic strategies

Novel platform has potential to detect many disease-related biomarkers in just one test

Study reveals the role of lncRNAs in immune dysfunction during severe COVID-19

A new concept for quickly detecting the presence of viruses

Researchers investigate how oxygen radicals protect against cancer

Preoperative sarcopenia and exercise intolerance predict outcomes following lung cancer surgery

The potential of CRISPR-based diagnostic assays and treatment approaches against COVID-19

A detailed look at two cases of symptomatic COVID in vaccinated individuals

Researchers create a cell library to study how various sugars bind to and interact with receptors

eBook: A guide to RNA sequencing eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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