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Pollutant from forest and crop fires induces genetic damage in human lung cells

When exposed in a laboratory to pollution levels comparable to those found in the atmosphere of the Amazon region during the forest and crop burning season, human lung cells suffer severe DNA damage and stop dividing. After 72 hours of exposure, over 30% of the cultured cells are dead.

24 Oct 2017

Chromosomes may be entangled, research finds

Everyone knows that long bits of yarn, or charging cables and the like, tend to get quickly tangled and form nasty knots. Little is known about the structures of our genetic material, chromosomes, which also consist of long strings that -- according to our experience -- should be likely to become knotted. However, up to now it has not been possible to study this experimentally.

20 Oct 2017

Small RNA molecules trigger cancer cells to commit suicide

Small RNA molecules originally developed as a tool to study gene function trigger a mechanism hidden in every cell that forces the cell to commit suicide, reports a new Northwestern Medicine study, the first to identify molecules to trigger a fail-safe mechanism that may protect us from cancer.

19 Oct 2017

UAB researchers report major advance in efforts to repair damaged heart after heart attack

University of Alabama at Birmingham biomedical engineers report a significant advance in efforts to repair a damaged heart after a heart attack, using grafted heart-muscle cells to create a repair patch.

17 Oct 2017

Study sheds light on complex process involved in development of sperm stem cells

New research from scientists at Huntsman Cancer Institute at the University of Utah and collaborators at University of Utah Health sheds light on the complex process that occurs in the development of human sperm stem cells.

5 Oct 2017

Novel agents appear to halt growth and progression of Ewing sarcoma

When combined with an already FDA-approved chemotherapy, a novel agent developed by researchers at Georgetown Lombardi Comprehensive Cancer Center, appears to halt the ability of Ewing sarcoma to grow and progress.

4 Oct 2017

Trial identifies genetic fault that affects treatment response in leukemia patients

A genetic fault has been identified in people with an aggressive type of leukemia that can significantly affect how they respond to treatment.

27 Sep 2017

Scientists develop new method to reconstruct biological processes using image data

Researchers at the Helmholtz Zentrum München have developed a new method for reconstructing continuous biological processes, such as disease progression, using image data. The study was published in ‘Nature Communications’.

11 Sep 2017

Researchers define how cancer drug works in cells, mice and man

Science is very good at determining how drugs work in experimental models. New research out of Dartmouth's Norris Cotton Cancer Center led by Alan Eastman, PhD, helps to bridge the gap when it comes to ensuring that drugs work by the same mechanism in human patients.

7 Sep 2017

HHMI scientists expand access to new resource for studying pediatric cancers

Howard Hughes Medical Institute (HHMI) scientists have created an extensive resource for studying pediatric cancers, which they are sharing widely to help accelerate research.

30 Aug 2017

Heat therapy could be promising treatment to help fight against cancer, autoimmune problems

Heat therapy may be a promising treatment in the fight against cancer, autoimmune problems and efforts to avoid organ rejection in transplant patients, according to researchers at the University of Kentucky.

30 Aug 2017

Biomedical engineering researchers aim to attack two banes of cardiovascular disease

Biomedical engineering researchers will attack two banes of cardiovascular disease -; heart failure after heart attacks and the scourge of resistant high blood pressure -; with $4.8 million in National Institutes of Health grants that begin this fall.

26 Aug 2017

Scientists uncover stem cell response to prolonged irradiation

Researchers from several Russian institutes, including MIPT, have found out how prolonged exposure to ionizing radiation affects human stem cells.

24 Aug 2017

Researchers discover potential way to trigger regeneration, repair of damaged heart cells

New research has discovered a potential means to trigger damaged heart cells to self-heal. The discovery could lead to groundbreaking forms of treatment for heart diseases.

21 Aug 2017

Case Western Reserve University professor awarded $150,000 for pediatric cancer research

In the United States, more children are lost to cancer than any other disease, and one in 285 children will be diagnosed before they turn 20.

27 Jul 2017

Ground-breaking new breast cancer drugs have manageable toxicity profile for most patients

A ground-breaking new class of oral drugs for treating breast cancer, known as cyclin-dependent kinase (CDK) inhibitors, are generally well-tolerated, with a manageable toxicity profile for most patients.

13 Jul 2017

Researchers get closer to finding out how cells and their nucleus grow at constant ratio

Over a century since scientists first observed that cells and their nucleus grow at a constant ratio to each other, we are now closer to finding out how.

11 Jul 2017

Brazilian researchers reveal nanoparticle-based strategy to combat antibiotic-resistant bacteria

A new strategy to combat antibiotic-resistant bacteria has been described by Brazilian researchers in Scientific Reports, an online journal owned by Springer Nature.

11 Jul 2017

Prolonged use of cancer inhibitors can lead to severe cardiovascular problems

Plk1 inhibitors have recently been acknowledged as an "Innovative Therapy for leukaemia" by the US Food and Drug Administration.

10 Jul 2017

Dmrta2 gene mutation can lead to abnormal brain development in unborn babies

Researchers from Cardiff University and Université Libre de Bruxelles have identified how the function of a key gene significantly impacts nerve stem cell growth, and how it can lead to abnormal brain development in unborn babies if the system goes awry.

6 Jul 2017