Lymph Node News and Research

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Lymph is clear or white fluid that travels through vessels, moves within tissues and work to keep all the parts of the body clean. After passing through the channels of the lymphatic system they drain into the lymph nodes. The lymph nodes act as filters along the lymphatic system. These nodes trap germs like bacteria, viruses, toxins as well as cancer cells and ensure that these are removed from the body.

Post-treatment imaging can help detect recurrences of HPV-positive oropharyngeal cancer

For patients treated with definitive radiation therapy (RT) for oropharyngeal cancer caused by human papillomavirus (HPV), the majority of recurrences can be detected by post-treatment imaging at three months and physical exams during the six months following treatment, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Uninsured and Medicaid patients have higher overall and cancer-specific mortality rates

Compared to patients with non-Medicaid insurance, uninsured patients and patients with Medicaid are more likely to present with advanced stages of head and neck cancer and have higher overall and cancer-specific mortality rates, according to research presented at the 2016 Multidisciplinary Head and Neck Cancer Symposium.

19 Feb 2016

Most stage III melanoma patients do not benefit from interferon treatment

Final results for the Sunbelt Melanoma Trial, published online this month in the Journal of Clinical Oncology, show that thanks to current diagnostic techniques, most stage III melanoma patients do not benefit from treatment with interferon.

15 Feb 2016

UAB discovery may offer new therapeutic approaches to asthma

University of Alabama at Birmingham researchers have found a previously unknown step in the pathway that leads to asthma, a discovery that may offer new therapeutic approaches to this incurable disease. Asthma affects more than 25 million people in the United States, including about 7 million children.

27 Jan 2016

New footage shows how AIDS vaccine candidate recruits immune cells to destroy infected cells

Using innovative technology, scientists from the Institut Pasteur and Inserm have filmed in vivo the process by which an AIDS vaccine candidate, developed by the French Vaccine Research Institute and the ANRS, triggers the immune response.

23 Dec 2015

Adjuvant chemotherapy not beneficial for patients with luminal A subtype of breast cancer

Premenopausal women whose invasive breast cancers were of the luminal A subtype had comparable 10-year disease-free survival rates regardless of whether or not they received adjuvant chemotherapy, according to data from the phase III DBCG77B clinical trial presented at the 2015 San Antonio Breast Cancer Symposium, held Dec. 8-12.

11 Dec 2015

Endomag’s new magnetic technology provides equivalent detection rates to current standards of cancer care

A global shortage of the most commonly used radioisotope in medical diagnostic procedures, Technetium-99 (99mTc), will have a major impact on hospitals around the world within the next year.

1 Dec 2015

Cornell biomedical engineers develop 'super natural killer cells' to destroy cancer cells in lymph nodes

Cornell biomedical engineers have developed specialized white blood cells - dubbed "super natural killer cells" - that seek out cancer cells in lymph nodes with only one purpose: destroy them.

13 Nov 2015

Study finds no consistent evidence that antidepressants increase complications after plastic surgery

For patients undergoing plastic surgery procedures, there's no consistent evidence that taking antidepressants increases the risk of bleeding, breast cancer, or other adverse outcomes, concludes a research review in the November issue of Plastic and Reconstructive Surgery, the official medical journal of the American Society of Plastic Surgeons.

31 Oct 2015

Imlygic approved for treatment of melanoma lesions in the skin and lymph nodes

The U.S. Food and Drug Administration today approved Imlygic (talimogene laherparepvec), the first FDA-approved oncolytic virus therapy, for the treatment of melanoma lesions in the skin and lymph nodes.

28 Oct 2015

Researchers find protein that plays crucial role in development of allergic airway inflammation

Allergies are becoming more commonplace, particularly in industrialised coun-tries. In addition to hay fever, allergic asthma is currently considered to be one of the most widespread allergies. UFZ researchers and their colleagues from the University of Leipzig have recently been successful in finding a protein that plays a critical role in the development of allergic airway inflammation.

12 Oct 2015

New smartphone-based device can reliably perform molecular diagnoses at low cost

NIBIB-funded researchers at the Massachusetts General Hospital have developed a smartphone-based device that can reliably carry out molecular diagnoses in under an hour for approximately two dollars per patient. The device could enable point-of-care cancer diagnostics in low- to middle-income or remote areas, which often have high rates of mortality from cancer due to missed opportunities for treatment.

6 Oct 2015

Intratumoral morphological diversity of breast cancer not related to chromosome aberrations

Intratumor morphological heterogeneity (diversity) of breast cancer is not related to chromosome aberrations. This conclusion was made based on the study of one case with aggressive variant of breast cancer - invasive micropapillary carcinoma by researchers from Tomsk State University, Tomsk Cancer Research Institute, and Institute of Medical Genetics.

30 Sep 2015

Kolltan announces presentation of data from KTN0158 preclinical study in mast cell tumors at ESMO 2015

Kolltan Pharmaceuticals, Inc. today announced the presentation of data from a preclinical study evaluating KTN0158 in dogs with spontaneous mast cell tumors. KTN0158 is a proprietary, humanized anti-KIT IgG1 monoclonal antibody drug candidate being developed as a potential therapy for cancer and mast cell-related diseases.

28 Sep 2015

Genetic test that predicts recurrence of breast cancer may impact use of chemotherapy

A genetic test that helps predict whether some women's breast cancer will recur might influence how chemotherapy is used, according to a study from Duke Medicine.

28 Aug 2015

Study sheds light on helper cells and killer cells

Scientists at the University of Bonn, together with colleagues from the USA and Japan, have shed light on an important immune mechanism. Their work shows how the body provides the important killer cells with a helper in the case of an infection. The study could point the way to better vaccines in the future.

21 Aug 2015

New MRI contrast agent detects tiny breast cancer tumors, micrometastases

Researchers at Case Western Reserve University have developed a magnetic resonance imaging (MRI) contrast agent that detects much smaller aggressive breast cancer tumors and micrometastases than current agents can identify.

13 Aug 2015

New approach may offer improved way to detect early breast cancer

Researchers have shown that magnetic resonance imaging (MRI) can detect the earliest signs of breast cancer recurrence and fast-growing tumors. Their approach detects micromestastases, breakaway tumor cells with the potential to develop into dangerous secondary breast cancer tumors elsewhere in the body.

12 Aug 2015

Lightpoint Medical receives R01 grant from US National Cancer Institute

Lightpoint Medical, an innovative medical device company specializing in imaging technologies announced today that it has received an R01 grant of $2.6M million from the US National Cancer Institute. The funding will support clinical trials of Lightpoint's EnLight™ molecular imaging technology in lymph node cancer and a range of gynecologic cancers at Memorial Sloan Kettering Cancer Center.

6 Aug 2015

EORTC study: Irradiation of regional nodes in breast cancer patients has marginal effect on overall survival

At a median follow-up of 10.9 years, an EORTC study has shown that irradiation of regional nodes in patients with stage I, II, or III breast cancer has a marginal effect on overall survival, the primary endpoint (at 10 years, overall survival was 82.3 % for regional irradiation versus 80.7% for no regional irradiation, (HR=0.87 (95%CI: 0.76, 1.00), p=0.06).

4 Aug 2015