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Study highlights new treatment options for neurodevelopmental disorders like TSC

Clemson University scientists are working to determine how neurons are generated, which is vital to providing treatment for neurological disorders like Tuberous Sclerosis Complex (TSC).

23 Oct 2013

U of T researchers develop method to screen human stem cells

University of Toronto researchers have developed a method that can rapidly screen human stem cells and better control what they will turn into. The technology could have potential use in regenerative medicine and drug development. Findings are published in this week's issue of the journal Nature Methods.

23 Oct 2013

P400 predicts RCC outcome

Reduced expression of a senescence-associated protein is associated with worse outcome in patients with renal cell carcinoma, study findings show.

22 Oct 2013

Prognostic factors could aid RCC metastasectomy decisions

Researchers have identified four factors that are associated with survival time in patients who undergo metastasectomy for metastatic renal cell carcinoma.

22 Oct 2013

Stage and grade dominate RCC outcomes

Tumor grade and American Joint Committee on Cancer stage have emerged as the most important predictors of mortality in a competing risks analysis of patients undergoing nephrectomy for renal cell carcinoma.

22 Oct 2013

Amgen Buys Roche Rights To Neutropenia Drugs

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22 Oct 2013

Sanofi uses QUOSA's literature management tools to automate adverse event monitoring

Elsevier, a world-leading provider of scientific, technical and medical information products and services, today announced that Sanofi, one of the world's leading pharmaceutical organizations, has implemented QUOSA's literature management tools to automate adverse event monitoring.

22 Oct 2013

FDA grants orphan drug designation to Aduro's CRS-207 for treatment of pancreatic cancer

Aduro BioTech, Inc. announced today that the Office of Orphan Products Development of the Food and Drug Administration has granted orphan drug designation for CRS-207, a novel immunotherapy, for the treatment of pancreatic cancer.

22 Oct 2013

AstraZeneca begins selumetinib Phase 3 clinical trial in NSCLC patients

AstraZeneca today announced the first patient randomized in a Phase 3 clinical trial for selumetinib, an oral, potent, selective MEK inhibitor, being investigated as second-line therapy in patients with advanced or metastatic non-small-cell lung cancer whose tumors are KRAS mutation-positive.

22 Oct 2013

Scientists highlight novel way to develop universal influenza vaccine that can protect against multiple flu strains

A study led by St. Jude Children's Research Hospital scientists highlights a new approach for developing a universal influenza vaccine that could protect against multiple flu strains, including deadly pandemic strains. The research appears today in the advance online edition of the scientific journal Nature Immunology.

22 Oct 2013

Study finds no evidence that stem cell therapy improves vision for children with ONH

A study performed at Children's Hospital Los Angeles found no evidence that stem cell therapy improves vision for children with optic nerve hypoplasia. Their results are reported in the Journal of the American Association for Pediatric Ophthalmology and Strabismus.

22 Oct 2013

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

he major genetic risk factor for Alzheimer's disease (AD), present in about two-thirds of people who develop the disease, is ApoE4, the cholesterol-carrying protein that about a quarter of us are born with. But one of the unsolved mysteries of AD is how ApoE4 causes the risk for the incurable, neurodegenerative disease.

22 Oct 2013

Clinical trials will help to develop treatment and follow-up of COPD patients

Three major clinical trials will help to develop and target treatment and follow-up of patients suffering from COPD, lung cancer and rheumatoid arthritis in Norway.

22 Oct 2013

Nanopharmaceutical drug shows promise for cancers that resist antiangiogenic drugs

The nanopharmaceutical drug CRLX101 is showing promise as a potential new treatment for cancers that develop resistance to antiangiogenic drugs and radiation therapy, according to clinical trial results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19 - 23.

22 Oct 2013

Breast milk may protect babies from acquiring HIV infection, say researchers

A substance in breast milk that neutralizes HIV and may protect babies from acquiring HIV from their infected mothers has been identified for the first time by researchers at Duke Medicine.

22 Oct 2013

Research: Low levels of vitamin D appear to increase child's risk of anemia

Low levels of the "sunshine" vitamin D appear to increase a child's risk of anemia, according to new research led by investigators at the Johns Hopkins Children's Center. The study, published online Oct. 10 in the Journal of Pediatrics, is believed to be the first one to extensively explore the link between the two conditions in children.

22 Oct 2013

Study opens doors to novel treatments for aggressive brain cancer

Ludwig researchers have elucidated a key mechanism by which cancer cells change how they metabolize glucose to generate the energy and raw materials required to sustain runaway growth.

22 Oct 2013

Pancreatic cancer patients may benefit from antibody-drug conjugates

Patients with pancreatic cancer may benefit from an investigational member of an emerging class of anticancer drugs called antibody-drug conjugates, according to preclinical results presented here at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics, held Oct. 19-23.

22 Oct 2013

CUMC develops new technique that uses patient's own cells to grow new hair

Researchers at Columbia University Medical Center (CUMC) have devised a hair restoration method that can generate new human hair growth, rather than simply redistribute hair from one part of the scalp to another.

22 Oct 2013

UH professor awarded $1.56M NCI grant to explore preventive therapy against colon cancer

As the second leading cause of cancer-related deaths in the U.S., colon cancer affects both men and women and is expected to cause more than 50,000 deaths this year. University of Houston professor Cecilia Williams has been awarded a $1.56 million grant from the National Cancer Institute to investigate the mechanistic basis for novel colon cancer prevention and therapy.

22 Oct 2013

Cell News and Research

Study highlights new treatment options for neurodevelopmental disorders like TSC

U of T researchers develop method to screen human stem cells

P400 predicts RCC outcome

Prognostic factors could aid RCC metastasectomy decisions

Stage and grade dominate RCC outcomes

Amgen Buys Roche Rights To Neutropenia Drugs

Sanofi uses QUOSA's literature management tools to automate adverse event monitoring

FDA grants orphan drug designation to Aduro's CRS-207 for treatment of pancreatic cancer

AstraZeneca begins selumetinib Phase 3 clinical trial in NSCLC patients

Scientists highlight novel way to develop universal influenza vaccine that can protect against multiple flu strains

Study finds no evidence that stem cell therapy improves vision for children with ONH

Buck Institute finds link between ApoE4 and anti-aging protein targeted by resveratrol in red wine

Clinical trials will help to develop treatment and follow-up of COPD patients

Nanopharmaceutical drug shows promise for cancers that resist antiangiogenic drugs

Breast milk may protect babies from acquiring HIV infection, say researchers

Research: Low levels of vitamin D appear to increase child's risk of anemia

Study opens doors to novel treatments for aggressive brain cancer

Pancreatic cancer patients may benefit from antibody-drug conjugates

CUMC develops new technique that uses patient's own cells to grow new hair

UH professor awarded $1.56M NCI grant to explore preventive therapy against colon cancer

How to optimize your cell line development eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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