Transplant News and Research

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DATATRAK announces technology and services agreement with Bellicum

DATATRAK International, Inc., a technology and services company focused on global eClinical solutions for the clinical trials industry, today announced the award of a multi-million dollar, five-year technology and services agreement with Bellicum Pharmaceuticals.

11 Sep 2012

Blood flow simulation tools can test and optimize Berlin Heart design

Structural and mechanical engineers at the University of California, San Diego, are working together to create blood flow simulations that could lead to improvements in the design of a cardiac pump for children born with heart defects. They hope that the design changes will improve young patients' outcomes.

11 Sep 2012

Cardiac stem cells from newborns show stronger regenerative ability

Researchers at the University of Maryland School of Medicine, who are exploring novel ways to treat serious heart problems in children, have conducted the first direct comparison of the regenerative abilities of neonatal and adult-derived human cardiac stem cells.

11 Sep 2012

Cell Therapeutics launches Pixuvri in the European Union

Cell Therapeutics, Inc., a company focused on translating science into novel cancer therapies, today announced the initiation of the commercial launch of Pixuvri in the European Union with entry into Sweden, Denmark and Finland in September, to be followed by Austria and Norway in early October 2012 and Germany, United Kingdom and the Netherlands in November 2012.

11 Sep 2012

Warning over sirolimus in HCV-positive liver transplantation

Sirolimus, whether given at the time of liver transplantation or after, is associated with poorer outcomes in patients with hepatitis C virus infection compared with those who do not take the immunosuppressant, shows a US study.

10 Sep 2012

Researchers identify three genetic regions associated with primary biliary cirrhosis

Researchers have newly identified three genetic regions associated with primary biliary cirrhosis (PBC), the most common autoimmune liver disease, increasing the number of known regions associated with the disorder to 25.

10 Sep 2012

People with kidney stones more likely to need dialysis or transplant later in life

People who have had kidney stones are twice as likely to need dialysis or a kidney transplant later in life, demonstrates recently published findings by medical researchers at the University of Alberta. Their article was recently published in the British Medical Journal.

7 Sep 2012

Study finds excellent outcomes for patients with acute liver failure after LDLT

Patients in Japan who underwent living donor liver transplantation (LDLT) for acute liver failure (ALF) were classified as having excellent outcomes, with ten-year survival at 73%.

7 Sep 2012

Longer looks: Insurers balk at price of new asthma relief; Despite health law, costs still overwhelming for some patients

For two decades, Patricia DiGiusto struggled with severe asthma. Powerful medications and frequent use of her inhaler could not prevent repeated trips to the emergency room. ... Two years ago, Ms. DiGiusto's doctor told her about a new procedure called bronchial thermoplasty, the first non-drug therapy approved by the Food and Drug Administration for patients with severe asthma.

7 Sep 2012

Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

A team of scientists led by a bone marrow transplant researcher at Fred Hutchinson Cancer Research Center has shed new light on why most bone marrow transplant patients who receive tissue-matched cells from unrelated donors still suffer acute graft-versus-host disease (GVHD).

6 Sep 2012

Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today complete results from its Phase IIb trial with ALN-RSV01 for the treatment of respiratory syncytial virus (RSV) infection in lung transplant patients.

6 Sep 2012

Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus

Rigel Pharmaceuticals, Inc. today announced that it has commenced Phase 2 clinical studies with two of the company's most advanced proprietary therapeutic product candidates. R343 is an inhaled SYK inhibitor that is being evaluated as a potential treatment for allergic asthma.

6 Sep 2012

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

Soligenix, Inc., a development stage biopharmaceutical company, announced today that the National Cancer Institute has awarded Soligenix a Small Business Innovation Research grant to support the conduct of a Phase 2 clinical trial designed to evaluate orBec (oral beclomethasone 17,21-dipropionate or BDP) as a treatment for the gastrointestinal manifestation of chronic Graft-versus-Host disease.

5 Sep 2012

New health insurance product from ICICI Lombard

ICICI Lombard General Insurance Company Ltd., the country's largest private sector general insurance company, announced the launch of a unique health insurance product called "ICICI Lombard Complete Health Insurance".

4 Sep 2012

Triple-threat approach can reduce invasive bloodstream infections in pediatric cancer patients

Hospitals can dramatically reduce the number of life-threatening central line infections in pediatric cancer patients by following a set of basic precautions, by encouraging families to speak up when they observe noncompliance with the protocol and by honest analysis of the root cause behind every single infection, according to a new Johns Hopkins Children's Center study.

3 Sep 2012

Missing link between bone marrow stem cells and human immune system

UCLA researchers have discovered a type of cell that is the "missing link" between bone marrow stem cells and all the cells of the human immune system, a finding that will lead to a greater understanding of how a healthy immune system is produced and how disease can lead to poor immune function.

3 Sep 2012

MDA7 compound shows promise against Alzheimer's disease

A compound developed to treat neuropathic pain has shown potential as an innovative treatment for Alzheimer's disease, according to a study by researchers at Cleveland Clinic's Lerner Research Institute and Anesthesiology Institute.

3 Sep 2012

Potential new COPD drug

A study led by researchers at Boston University School of Medicine (BUSM) has shown that a compound used in some skin creams may halt the progression of emphysema and reverse some of the damage caused by the disease. When the compound Gly-His-Lys (GHK) was applied to lung cells from patients with emphysema, normal gene activity in altered cells was restored and damaged aspects of cellular function were repaired.

1 Sep 2012

UI Hospital surgeons perform first robotic-assisted kidney transplant and sleeve gastrectomy

Surgeons at the University of Illinois Hospital & Health Sciences System are developing new treatment options for obese kidney patients.

1 Sep 2012

Scientists show how pluripotent stem cells mobilize in wounded planarian worms

The skin, the blood, and the lining of the gut-adult stem cells replenish them daily. But stem cells really show off their healing powers in planarians, humble flatworms fabled for their ability to rebuild any missing body part. Just how adult stem cells build the right tissues at the right times and places has remained largely unanswered.

1 Sep 2012

Transplant News and Research

DATATRAK announces technology and services agreement with Bellicum

Blood flow simulation tools can test and optimize Berlin Heart design

Cardiac stem cells from newborns show stronger regenerative ability

Cell Therapeutics launches Pixuvri in the European Union

Warning over sirolimus in HCV-positive liver transplantation

Researchers identify three genetic regions associated with primary biliary cirrhosis

People with kidney stones more likely to need dialysis or transplant later in life

Study finds excellent outcomes for patients with acute liver failure after LDLT

Longer looks: Insurers balk at price of new asthma relief; Despite health law, costs still overwhelming for some patients

Study sheds new light on why most bone marrow transplant patients suffer acute GVHD

Alnylam announces complete results from ALN-RSV01 Phase IIb trial on RSV infection

Rigel commences R343 and R333 Phase 2 studies in allergic asthma, discoid lupus erythematosus

NCI awards Soligenix $300,000 SBIR grant for orBec Phase 2 chronic GI GVHD trial

New health insurance product from ICICI Lombard

Triple-threat approach can reduce invasive bloodstream infections in pediatric cancer patients

Missing link between bone marrow stem cells and human immune system

MDA7 compound shows promise against Alzheimer's disease

Potential new COPD drug

UI Hospital surgeons perform first robotic-assisted kidney transplant and sleeve gastrectomy

Scientists show how pluripotent stem cells mobilize in wounded planarian worms

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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