Immune System News and Research

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Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Researchers at Charité - Universitätsmedizin Berlin and TU Berlin as well as the University of Oslo have developed a new tissue-section analysis system for diagnosing breast cancer based on artificial intelligence (AI).

10 Mar 2021

Study reveals novel approach to reduce the risk of thrombosis by using IgM antibodies

Thrombotic occlusion of blood vessels, which leads to myocardial infarctions, strokes and venous thromboembolisms, is the major cause of death in the western hemisphere.

9 Mar 2021

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in the United States.

9 Mar 2021

Translational research results in promising combination therapeutic candidate for type 1 diabetes

Translational research led by scientists at La Jolla Institute for Immunology (LJI) has resulted in a promising combination therapeutic candidate for adults with recent-onset type 1 diabetes.

9 Mar 2021

Study describes the infection of human cells by intestinal pathogen during spaceflight

Astronauts face many challenges to their health, due to the exceptional conditions of spaceflight. Among these are a variety of infectious microbes that can attack their suppressed immune systems.

9 Mar 2021

CBD ameliorates cognitive function in experimental model of familial Alzheimer's

A two-week course of high doses of CBD helps restore the function of two proteins key to reducing the accumulation of beta-amyloid plaque, a hallmark of Alzheimer's disease, and improves cognition in an experimental model of early onset familial Alzheimer's, investigators report.

9 Mar 2021

Inhibition of complement disrupts neurodegeneration, improves cognitive function in TBI patients

Traumatic brain injury (TBI) is a major cause of disability and a risk factor for early-onset dementia. The injury is characterized by a physical insult followed acutely by complement driven neuroinflammation.

9 Mar 2021

UMD receives grant to explore nettle as a functional food for improving health

Obesity, diabetes, and overall immune system health are issues that are all top-of-mind right now, especially during the pandemic.

8 Mar 2021

Current vaccines and therapies may be less effective at neutralizing new SARS-CoV-2 variants

A new study of the U.K. and South Africa variants of SARS-CoV-2 predicts that current vaccines and certain monoclonal antibodies may be less effective at neutralizing these variants and that the new variants raise the specter that reinfections could be more likely.

8 Mar 2021

How do viruses evolve in bats?

Bats have played a crucial epidemiological role in the evolution of many viruses and house many coronaviruses. Until 2002, coronaviruses had been known to cause mild respiratory ailments in human beings. However, this notion changed in the same year when a bat-borne virus caused the severe acute respiratory syndrome (SARS) pandemic.

8 Mar 2021

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

The currently developed vaccines against SARS-CoV-2 include the RBD in their immunogen. With a similar objective, a new study developed an RBD protein-based vaccine candidate against the SARS-CoV-2, using self-assembling Helicobacter pylori-bullfrog ferritin nanoparticles as an antigen delivery system. The study is published recently in the journal mBio (by the American Society of Microbiology).

8 Mar 2021

CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients

A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.

8 Mar 2021

Researchers identify new biomarkers associated with severity of COVID-19

A team of researchers from the CHUM Research Centre has identified new biomarkers associated with the severity of COVID-19 in infected patients.

8 Mar 2021

Radiotherapy-resistant cancers could be rendered susceptible through immunotherapy treatment

Cancers that are resistant to radiotherapy could be rendered susceptible through treatment with immunotherapy, a new study suggests.

8 Mar 2021

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

Diffuse large B-cell lymphoma (DLBCL) is an aggressive cancer of lymphocytes, and a large proportion of patients are either unresponsive or develop resistance towards R-CHOP—the standard treatment regimen.

8 Mar 2021

New, efficient method facilitates antibody development

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases.

5 Mar 2021

Combined liver-cytokine humanization enhances human red blood cell production and survival

In a new study by the Yale Department of Immunobiology and Yale Cancer Center, researchers report combined liver and growth factor humanization enhances human red blood cell production and survival in circulation the immunodeficient murine host.

5 Mar 2021

Researchers describe new approach for hematopoietic stem cell transplant in embryos

Most people have heard of stem cells, cells from which all other cells with specialized functions are generated. Hematopoietic stem cells (HSCs) are the architects of blood cell development and are responsible for blood cell formation throughout the life of an organism.

5 Mar 2021

Researchers identify new molecular mechanisms in chronic skin inflammation

Frequently occurring chronic skin inflammation like in atopic dermatitis (AD or neurodermatitis) and psoriasis have different causes such as genetic predisposition, stress or allergens.

5 Mar 2021

SARS-CoV-2 proteins are potent suppressors of innate immunity

A new study describes the strong immune-suppressing activity of SARS-CoV-2 genes, among other coronavirus genes.

5 Mar 2021

Immune System News and Research

Researchers develop AI-based tissue-section analysis system to diagnose breast cancer

Study reveals novel approach to reduce the risk of thrombosis by using IgM antibodies

Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration

Translational research results in promising combination therapeutic candidate for type 1 diabetes

Study describes the infection of human cells by intestinal pathogen during spaceflight

CBD ameliorates cognitive function in experimental model of familial Alzheimer's

Inhibition of complement disrupts neurodegeneration, improves cognitive function in TBI patients

UMD receives grant to explore nettle as a functional food for improving health

Current vaccines and therapies may be less effective at neutralizing new SARS-CoV-2 variants

How do viruses evolve in bats?

Self-assembling nanoparticles an effective vaccine candidate for SARS-CoV-2

CAR T-cell therapy triples expected length of remission for relapsed multiple myeloma patients

Researchers identify new biomarkers associated with severity of COVID-19

Radiotherapy-resistant cancers could be rendered susceptible through immunotherapy treatment

Review helps understand the mechanisms of R-CHOP resistance in diffuse large B-cell lymphoma

New, efficient method facilitates antibody development

Combined liver-cytokine humanization enhances human red blood cell production and survival

Researchers describe new approach for hematopoietic stem cell transplant in embryos

Researchers identify new molecular mechanisms in chronic skin inflammation

SARS-CoV-2 proteins are potent suppressors of innate immunity

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