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COVID-19 related placental tissue destruction and insufficiency may cause stillbirth and neonatal death from hypoxic-ischemic injury

Researchers evaluate the role of the placenta in causing stillbirth and neonatal death post-maternal COVID-19 and confirmed placental positivity for SARS-CoV-2.

16 Feb 2022

Inside the tactical tug of war over the controversial Alzheimer’s drug

The drug industry, patient advocates, and congressional Republicans have all attacked federal officials' decision to decline routine Medicare coverage for a controversial Alzheimer's drug.

16 Feb 2022

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022

UK's fight against zoonotic diseases receives a £200 million boost

The UK's fight against zoonotic diseases, including avian flu and bovine tuberculosis received a major boost today (16 February) with the allocation of £200 million for a programme of investment into world leading research facilities.

15 Feb 2022

New tool appears to accurately identify patients at risk of death from alcohol-associated hepatitis

Mayo Clinic researchers have developed a new scoring system to help health care professionals predict the 30-day mortality risk for patients with alcohol-associated hepatitis, and the tool appears to more accurately identify patients at highest risk of death and those likely to survive.

15 Feb 2022

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Researchers identify and investigate the presence and evolution of the SARS-CoV-2 N and S glycoprotein proteins.

15 Feb 2022

Researchers create a comprehensive atlas of cerebrovascular cell types

While neurons and glial cells are by far the most numerous cells in the brain, many other types of cells play important roles. Among those are cerebrovascular cells, which form the blood vessels that deliver oxygen and other nutrients to the brain.

15 Feb 2022

Lifting mask mandates in elementary schools in the U.S. may be too early, study finds

Before lifting mask mandates in elementary schools in the U.S., local COVID-19 case rates should be far below current rates to avoid the risk of increased transmission among students, staff, and families, according to a study led by researchers at Harvard T.H. Chan School of Public Health and Massachusetts General Hospital.

15 Feb 2022

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Researchers from the National Cancer Centre Singapore (NCCS) have found a potential new strategy to treat peritoneal carcinomatosis, a metastatic form of intra-abdominal cancer, where patients are presented with limited treatment options and poor overall survival.

15 Feb 2022

Older woman's estrogen levels may be linked to risk of COVID-19 death

An older woman's estrogen levels may be linked to her chances of dying from COVID-19, with higher levels of the hormone seemingly protective against severe infection, suggests research published in the open access journal BMJ Open.

15 Feb 2022

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

A novel combination treatment approach extended survival in mice with pancreatic cancer, demonstrating a potential second-line therapy for patients, according to findings published in Proceedings of the National Academy of Sciences.

15 Feb 2022

Study investigates whether SARS-CoV-2 infection is associated with increased risk of incident type 1 diabetes

A recent study has demonstrated that although the incidence of type 1 diabetes increases among children during the COVID-19 pandemic, previous infection by SARS-CoV-2 does not directly act as a causal factor.

15 Feb 2022

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

A recent study described COVID-19 sequelae developed in non-hospitalized young adults more than six months after COVID-19 infection.

15 Feb 2022

Estimates of COVID-19 hospitalization and ICU burden from existing severe acute respiratory infections surveillance

Researchers estimated SARS-CoV-2 hospitalization and ICU treatment during the first three waves of the COVID-19 pandemic.

15 Feb 2022

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

Single-cell RNA sequencing, or "scRNA-seq" for short, is a technique that allows scientists to study the expression of genes in an individual cell within a mixed population – which is virtually how all cells exist in the body's tissues.

15 Feb 2022

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

While the word "mutation" may conjure up alarming notions, a mutation in brain immune cells serves a positive role in protecting people against Alzheimer's disease.

14 Feb 2022

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Findings by researchers from Germany support the view that hyperactive immune cells in the brain can have a protective effect in the course of neurodegenerative diseases.

14 Feb 2022

Trauma centers expand care to treat patients with mental health and substance use disorders

Most patients who show signs of alcohol or opioid/stimulant drug use associated with injury now undergo screening and/or intervention in Level I and II trauma centers, according to national survey results.

14 Feb 2022

Discovery may lead to new treatment approach for people with alcohol-associated liver disease

Investigators at Cedars-Sinai have uncovered a new pathway that helps explain how consuming too much alcohol causes damage to the liver, specifically mitochondrial dysfunction in alcohol-associated liver disease.

14 Feb 2022

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

Following up on a 2018 study that identified an epigenetic modifier known as histone deacetylase 11 (HDAC11) as a potential therapeutic target for treating obesity and diabetes, researchers from the University of Colorado School of Medicine have published new research that finds HDAC11 regulates G protein-coupled receptors (GPCRs) called beta-adrenergic receptors (β-ARs).

14 Feb 2022

Laboratory News and Research

COVID-19 related placental tissue destruction and insufficiency may cause stillbirth and neonatal death from hypoxic-ischemic injury

Inside the tactical tug of war over the controversial Alzheimer’s drug

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

UK's fight against zoonotic diseases receives a £200 million boost

New tool appears to accurately identify patients at risk of death from alcohol-associated hepatitis

Prediction of SARS-CoV-2 epitope candidates for future vaccines

Researchers create a comprehensive atlas of cerebrovascular cell types

Lifting mask mandates in elementary schools in the U.S. may be too early, study finds

Researchers find potential new strategy to treat metastatic form of intra-abdominal cancer

Older woman's estrogen levels may be linked to risk of COVID-19 death

Novel combination therapeutic approach could increase survival of pancreatic cancer patients

Study investigates whether SARS-CoV-2 infection is associated with increased risk of incident type 1 diabetes

Study describes sequelae presenting more than six months after COVID-19 in non-hospitalized young adults

Estimates of COVID-19 hospitalization and ICU burden from existing severe acute respiratory infections surveillance

New DisCo method allows scRNA-seq to efficiently process samples with fewer cells

UCI biologists discover how a protective mutation may reduce Alzheimer's risk

Hyperactive microglia can have a protective effect in the course of neurodegenerative diseases

Trauma centers expand care to treat patients with mental health and substance use disorders

Discovery may lead to new treatment approach for people with alcohol-associated liver disease

Research lays the foundation for developing obesity drugs based on enhancing β-AR signaling

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