Pulmonary Embolism News and Research

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A pulmonary embolism is a sudden blockage in a lung artery. The cause is usually a blood clot in the leg called a deep vein thrombosis that breaks loose and travels through the bloodstream to the lung.

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

Isis Pharmaceuticals, Inc. announced the initiation of a Phase 2 comparator-controlled study evaluating ISIS-FXIRx in patients undergoing knee replacement surgery, also referred to as total knee arthroplasty (TKA).

29 Oct 2012

Neuraxial anesthesia should be promoted for bilateral total knee replacements: HSS

Using regional anesthesia rather than general anesthesia reduces the need for blood transfusions in patients undergoing bilateral total knee replacement, according to a new study by researchers at Hospital for Special Surgery, in New York City.

29 Oct 2012

Cough, difficulty breathing and chest pain key symptoms of pulmonary embolism

Difficulty breathing, chest pain, and cough may sound like symptoms of a heart attack; however, new research shows that these are the key symptoms for pulmonary embolism (PE), a potentially fatal blockage in the lung.

22 Oct 2012

Lenalidomide worsens survival, adverse events in prostate cancer

A combination of lenalidomide plus docetaxel and prednisone treatment in patients with chemotherapy-naive prostate cancer leads to worse overall survival rates and increased toxicity compared with placebo, show study results.

12 Oct 2012

Premier, ArjoHuntleigh announce three-year contract for vascular compression therapy systems

ArjoHuntleigh announced today that it has been awarded a three-year contract with Premier Purchasing Partners, L.P., the group purchasing unit of the Premier healthcare alliance, for its vascular compression therapy systems.

4 Oct 2012

Patients with RA more likely to develop venous thromboembolism

A study that included more than 45,000 residents of Sweden with rheumatoid arthritis finds that individuals with this disease had an associated higher risk of venous thromboembolism (a blood clot that forms within a vein), and that this elevated risk was stable for 10 years after the time of diagnosis, according to a study in the October 3 issue of JAMA.

3 Oct 2012

Warfarin therapy should not be stopped completely after GI bleeding

The decision to not resume warfarin therapy following a gastrointestinal bleeding event is linked to an increased risk for thrombosis and mortality, researchers suggest.

27 Sep 2012

Warfarin therapy should not be stopped completely after GI bleeding

The decision to not resume warfarin therapy following a gastrointestinal bleeding event is linked to an increased risk for thrombosis and mortality, researchers suggest.

25 Sep 2012

Arthroplasty wound complications linked to oral anticoagulant use

Multicenter research suggests that recovery from hip or knee arthroplasty may be significantly affected by choice of pharmaceutical thromboprophylaxis.

21 Sep 2012

Study analyzes effectiveness of ultrasonography in diagnosis and treatment of critical care patients

A study published in the October issue of Anesthesiology analyzed the effectiveness of ultrasound examination in the diagnosis and treatment of critical care patients. In particular, the study looked at the ability of ultrasound to detect hidden anomalies, prompt urgent changes in therapy, induce further testing or interventions, and confirm or modify diagnoses.

20 Sep 2012

Measures of kidney function may be linked to thrombosis

Estimated glomerular filtration rate and albumin-creatinine ratio are independently associated with venous thromboembolism, research suggests.

18 Sep 2012

Measures of kidney function may be linked to thrombosis

Estimated glomerular filtration rate and albumin-creatinine ratio are independently associated with venous thromboembolism, research suggests.

18 Sep 2012

Apixaban offers minor added benefit for adult patients after hip replacement

The clot-inhibiting drug apixaban was approved in May 2011 for the prevention of thrombosis (blood clots) after operations to replace a hip or knee joint.

18 Sep 2012

Important data from Pfizer’s lung cancer and RCC portfolios to be presented at ESMO Congress

Pfizer Oncology today announced that important data from its lung cancer and renal cell carcinoma (RCC) portfolios will be presented at the upcoming European Society for Medical Oncology (ESMO) Congress in Vienna, Austria, September 28 - October 2, 2012.

18 Sep 2012

Genetic test to help prescribe proper dose of blood-thinner warfarin

Patients suffering from dangerous blood clots will receive genetic testing to help health professionals at the University of Illinois Hospital & Health Sciences System prescribe the proper dose of the blood-thinner warfarin.

7 Sep 2012

EC grants marketing authorization for Pfizer’s INLYTA to treat renal cell carcinoma

Pfizer Inc. announced today that the European Commission (EC) has granted marketing authorization for INLYTA (axitinib) for the treatment of adult patients with advanced renal cell carcinoma (RCC), a type of kidney cancer, after failure of prior treatment with sunitinib or a cytokine.

4 Sep 2012

Some smaller clots may not require potentially risky treatment

Men and women who undergo joint replacement procedures, as well as those who have significant fractures, tend to be at an increased risk of developing pulmonary emboli (PE), blood clots that travel to the lungs where they may cause serious complications and even death.

1 Sep 2012

ICU misdiagnosis alarmingly common in the acute care setting

Each year as many as 40,500 critically ill U.S. hospital patients die with an unknown medical condition that may have caused or contributed to their death, Johns Hopkins patient safety experts report in a recent study.

28 Aug 2012

CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths

An international multi-site trial has launched to determine whether a common anti-inflammatory drug can reduce heart attacks, strokes, and deaths due to cardiovascular disease in people at high risk for them. This study is being supported by the National Heart, Lung, and Blood Institute (NHLBI), a part of the National Institutes of Health.

22 Aug 2012

Low blood anticoagulant levels increase risk for VTE

Low plasma levels of antithrombin, protein C, and protein S significantly increase the risk for venous thromboembolism, Italian research shows.

25 Jul 2012

Pulmonary Embolism News and Research

Further Reading

Isis commences ISIS-FXIRx Phase 2 study in knee replacement surgery patients

Neuraxial anesthesia should be promoted for bilateral total knee replacements: HSS

Cough, difficulty breathing and chest pain key symptoms of pulmonary embolism

Lenalidomide worsens survival, adverse events in prostate cancer

Premier, ArjoHuntleigh announce three-year contract for vascular compression therapy systems

Patients with RA more likely to develop venous thromboembolism

Warfarin therapy should not be stopped completely after GI bleeding

Warfarin therapy should not be stopped completely after GI bleeding

Arthroplasty wound complications linked to oral anticoagulant use

Study analyzes effectiveness of ultrasonography in diagnosis and treatment of critical care patients

Measures of kidney function may be linked to thrombosis

Measures of kidney function may be linked to thrombosis

Apixaban offers minor added benefit for adult patients after hip replacement

Important data from Pfizer’s lung cancer and RCC portfolios to be presented at ESMO Congress

Genetic test to help prescribe proper dose of blood-thinner warfarin

EC grants marketing authorization for Pfizer’s INLYTA to treat renal cell carcinoma

Some smaller clots may not require potentially risky treatment

ICU misdiagnosis alarmingly common in the acute care setting

CIRT to determine whether methotrexate can reduce heart attacks, strokes and CVD deaths

Low blood anticoagulant levels increase risk for VTE

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