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Recovery from bacterial pneumonia changes the infected lung cells, study shows

When people develop a respiratory infection, recovery from their illness leaves behind an immunological memory that influences how they will respond to later infections.

17 May 2017

Study highlights need to monitor transplant donor and recipient for identifying M. hominis infection

The way in which heart and lung transplant recipients acquired a specific species of bacteria, Mycoplasma hominis, had been previously undefined, and the bacterium was difficult to test.

16 May 2017

Study findings could pave way for better drugs to fight against parasitic infections

Immune cells, called macrophages, may rely on a compound to signal an attack to beat back attacks from parasitic worms, according to an international team of researchers, including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine.

12 May 2017

Study findings may help shed light on cause of systemic sclerosis

Americans and Norwegians with systemic sclerosis had higher levels of bacteria that can cause inflammation and lower levels of bacteria that are believed to protect against inflammation compared with healthy people, according to a new study by researchers from UCLA and Oslo University.

12 May 2017

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

The discovery of key signals that help tissues repair after injury could pave the way for new treatments for asthma and organ scarring, a study suggests.

12 May 2017

Scientists reveal how immune cells activate to kill parasitic worms

An international team of researchers including Zissis C. Chroneos, associate professor of pediatrics, and microbiology and immunology at Penn State College of Medicine, reveals how immune cells called macrophages activate to kill parasitic worms.

11 May 2017

CUMC researchers create new organoids that mimic features of full-sized lung

New lung "organoids"-tiny 3-D structures that mimic features of a full-sized lung- have been created from human pluripotent stem cells by researchers at Columbia University Medical Center. The team used the organoids to generate models of human lung diseases in a lab dish, which could be used to advance our understanding of a variety of respiratory diseases.

11 May 2017

Anti-smoking drug safe for COPD patients, research suggests

Medication that helps smokers to quit is safe for use by people with chronic lung conditions, research suggests.

10 May 2017

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

A common treatment for asthma, which is the most prevalent chronic childhood disease, requires use of an inhaler. But a big problem with inhalers, used to deliver steroids and other drugs in an aerosol form, is that children often don't operate them properly.

10 May 2017

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Certain blood vessels in the brainstem constrict when blood vessels elsewhere in the body would dilate. And that contrary behavior is what keeps us breathing, according to a new paper by UConn researchers published May 8 in eLife.

9 May 2017

Testosterone protects males against developing asthma, research reveals

An international research team has revealed for the first time that testosterone protects males against developing asthma, helping to explain why females are two times more likely to develop asthma than males after puberty.

8 May 2017

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Immunotherapy, which has achieved remarkable results in late-stage lung cancer patients, can also hold great hope for newly diagnosed patients, cutting the deadly disease off before it has the chance to take hold and offering a potential cure, according to a new Mount Sinai study published today in Cell.

4 May 2017

Scientists grow and purify earliest lung progenitors from human stem cells

Human lungs, like all organs, begin their existence as clumps of undifferentiated stem cells. But in a matter of months, the cells get organized. They gather together, branch and bud, some forming airways and others alveoli, the delicate sacs where our bodies exchange oxygen for carbon dioxide.

3 May 2017

Researchers create new tool that reveals insights into cellular development

Researchers at Columbia University Medical Center have created a new tool to describe the many possible ways in which a cell may develop. Rooted in the mathematical field of topology, the tool provides a roadmap that offers detailed insight into how stem cells give rise to specialized cells.

2 May 2017

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

A novel gene therapy using CRISPR genome editing technology effectively targets cancer-causing "fusion genes" and improves survival in mouse models of aggressive liver and prostate cancers, University of Pittsburgh School of Medicine researchers report in a study published online today in Nature Biotechnology.

2 May 2017

ARDS survivors who return to work end up losing their jobs, study finds

Forty-four percent of people who held jobs before contracting a condition called acute respiratory distress syndrome were jobless one year after they were discharged from the hospital, costing them an average of about $27,000 in earnings.

29 Apr 2017

Study examines economic impact of surviving acute respiratory distress syndrome

According to a new multicenter study, nearly half of previously employed adult survivors of acute respiratory distress syndrome were jobless one year after hospital discharge, and are estimated to have lost an average of $27,000 in earnings.

28 Apr 2017

Nanoparticles can travel from the lungs into bloodstream and reach susceptible areas of cardiovascular system

Tiny particles in air pollution have been associated with cardiovascular disease, which can lead to premature death. But how particles inhaled into the lungs can affect blood vessels and the heart has remained a mystery.

27 Apr 2017

Research offers new way to improve nanopharmaceuticals for personalized medicine

In a newly published study in Nature Nanotechnology, the shape and geometry of nanoparticles can have a significant impact in modulating adverse injection reactions and offer realistic solutions for patients receiving nanopharmaceuticals—drug delivery systems specializing in microscopic-particle drug combinations.

27 Apr 2017

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

Regenerative medicine using human pluripotent stem cells to grow transplantable tissue outside the body carries the promise to treat a range of intractable disorders, such as diabetes and Parkinson's disease.

26 Apr 2017

Lungs News and Research

Recovery from bacterial pneumonia changes the infected lung cells, study shows

Study highlights need to monitor transplant donor and recipient for identifying M. hominis infection

Study findings could pave way for better drugs to fight against parasitic infections

Study findings may help shed light on cause of systemic sclerosis

Discovery of key signals in the lungs and liver could pave way for immune disorder treatments

Scientists reveal how immune cells activate to kill parasitic worms

CUMC researchers create new organoids that mimic features of full-sized lung

Anti-smoking drug safe for COPD patients, research suggests

Scientists aim to revolutionize asthma treatment by replacing inhalers with new drug

Contrary behavior by blood vessels in the brainstem is what keeps us breathing, research suggests

Testosterone protects males against developing asthma, research reveals

New research identifies immunotherapy targets to offer hope for early-stage lung cancer patients

Scientists grow and purify earliest lung progenitors from human stem cells

Researchers create new tool that reveals insights into cellular development

Study: New gene editing strategy effectively targets cancer-causing ‘fusion genes’ in mouse models

ARDS survivors who return to work end up losing their jobs, study finds

Study examines economic impact of surviving acute respiratory distress syndrome

Nanoparticles can travel from the lungs into bloodstream and reach susceptible areas of cardiovascular system

Research offers new way to improve nanopharmaceuticals for personalized medicine

Study underscores need for genetic screening to improve safety of experimental stem cell treatments

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Automating research - solutions and best practices

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