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New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

Researchers at the Mount Sinai Center for Transformative Disease Modeling have released a groundbreaking study identifying 4,749 key gene clusters, termed "prognostic modules," that significantly influence the progression of 32 different types of cancer.

13 Nov 2023

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Intratumoral therapy – in which cancer drugs are injected directly into tumors – is a promising treatment option for solid cancers but has shown limited success in clinical trials due to an inability to precisely deliver the drug and because most immunotherapies quickly dissipate from the site of injection.

13 Nov 2023

Acupuncture may offer limited relief from chronic spontaneous urticaria, study finds

A randomized controlled trial that included more than 300 people diagnosed with chronic spontaneous urticaria (CSU), or hives, found that acupuncture may offer limited relief from the condition, but clinical significance of this finding was unclear.

13 Nov 2023

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

An observational study of patients being treated for acute COVID-19 in a multicenter health care system observed virologic rebound in about 20 percent of patients treated with nirmatrelvir-ritonavir (N-R) versus about 2 percent of those who did not receive treatment. The findings are published in Annals of Internal Medicine.

13 Nov 2023

New physical mechanism uncovered for breast cancer invasion

The majority of breast cancers start in the lining of a breast milk duct and, if they remain there, are very treatable.

13 Nov 2023

Multi-faceted implementation strategy significantly lowers blood pressure in low-income patients

Uncontrolled hypertension, the leading preventable risk factor for cardiovascular disease and premature deaths worldwide, disproportionately affects low-income populations.

13 Nov 2023

Novel assay may improve detection and treatment of acute myeloid leukemia

A novel assay that detects a unique molecular marker in patients with acute myeloid leukemia (AML) may revolutionize the way this disease is detected and treated according to a new report in The Journal of Molecular Diagnostics published by Elsevier.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins-;a medicine used to lower "bad" cholesterol levels-; increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

A new study by investigators from Mass General Brigham found that one in five individuals taking Nirmatrelvir-ritonavir therapy, commonly known as Paxlovid, to treat severe symptoms of COVID-19, experienced a positive test result and shedding of live and potentially contagious virus following an initial recovery and negative test-;a phenomenon known as virologic rebound.

13 Nov 2023

Study reveals underuse of antiviral medications in young children with influenza

Despite national medical guidelines supporting the use of antiviral medications in young children diagnosed with influenza, a new study reports an underuse of the treatment.

13 Nov 2023

Young people begin to use nicotine through vaping rather than through cigarettes

Young adults are now more likely to vape than to use traditional cigarettes. After years of public health success in decreasing the numbers of people using cigarettes, researchers are seeing striking increases in the numbers of young people who use e-cigarettes regularly – so much so that, for the first time, there are more young people who begin to use nicotine through vaping rather than through cigarettes.

13 Nov 2023

Intensive blood pressure treatment lowers risk of cardiovascular events in high-risk patients

An intensive three-year intervention to lower the top blood pressure number to less than 120 mm Hg was more effective at preventing death, heart attack, stroke and other cardiovascular events in adults at high risk for cardiovascular disease, compared to the standard treatment target of under 140 mm Hg, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Unlocking the cure for hepatitis B virus: Challenges and opportunities

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide.

13 Nov 2023

AI-based model can predict therapy outcome in ovarian cancer patients

A model based on artificial intelligence is able to predict the therapy outcome (measured by volumetric reduction of tumor lesions) in 80% of ovarian cancer patients.

13 Nov 2023

Major trial finds apixaban reduces stroke risk in patients with device-detected atrial fibrillation

The widely available blood thinner apixaban substantially reduced stroke in at-risk patients with a type of atrial fibrillation only detectable by a pacemaker or other implanted cardiac electronic device, a global study has found.

13 Nov 2023

Study finds rapid blood pressure reduction with low-sodium diet

Reducing daily sodium intake by around 4,000 mg/day significantly lowered systolic blood pressure in more than 70% of adults, ages 50 to 75, in as little as one week compared to their usual diet, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Intensive blood pressure control reduces dementia risk in adults with hypertension

An intensive, four-year blood-pressure intervention significantly reduced the risk of developing dementia among adults with high blood pressure compared to people who received usual care, in a study reported as late-breaking science today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

A new study by Hospital for Special Surgery (HSS) investigators has found that an initial high-risk antibody profile for antiphospholipid syndrome (APS) tended to remain high in pediatric patients.

13 Nov 2023

Abelacimab significantly reduces bleeding risk in atrial fibrillation patients with stroke risk

An experimental anti-clotting medication, abelacimab, significantly reduced bleeding among people with atrial fibrillation (or AFib) who were at risk of stroke, according to results of the AZALEA-TIMI 71 trial, presented today as late-breaking science at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Study shows long-term cardiovascular benefits of tight blood pressure control after pregnancy

Women with high blood pressure during pregnancy had long-term blood pressure and cardiac benefits if their blood pressure was carefully controlled for the first few weeks after having a baby, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Medicine News and Research

New study identifies 4,749 key gene clusters that influence progression of 32 cancer types

New gel delivery system overcomes challenges of intratumoral cancer immunotherapy

Acupuncture may offer limited relief from chronic spontaneous urticaria, study finds

Study observes virologic rebound in 20% of COVID-19 patients treated with nirmatrelvir-ritonavir

New physical mechanism uncovered for breast cancer invasion

Multi-faceted implementation strategy significantly lowers blood pressure in low-income patients

Novel assay may improve detection and treatment of acute myeloid leukemia

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

One in five individuals taking nirmatrelvir-ritonavir therapy found to experience rebound COVID

Study reveals underuse of antiviral medications in young children with influenza

Young people begin to use nicotine through vaping rather than through cigarettes

Intensive blood pressure treatment lowers risk of cardiovascular events in high-risk patients

Unlocking the cure for hepatitis B virus: Challenges and opportunities

AI-based model can predict therapy outcome in ovarian cancer patients

Major trial finds apixaban reduces stroke risk in patients with device-detected atrial fibrillation

Study finds rapid blood pressure reduction with low-sodium diet

Intensive blood pressure control reduces dementia risk in adults with hypertension

Initial high-risk antibody profile for antiphospholipid syndrome tends to remain high in pediatric patients, study finds

Abelacimab significantly reduces bleeding risk in atrial fibrillation patients with stroke risk

Study shows long-term cardiovascular benefits of tight blood pressure control after pregnancy

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