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New gene variant found in human and animal tissue offers a promising treatment for cancer

A novel gene variant found in human and animal tissue may be a promising treatment for cancer, including breast and brain cancer, according to scientists from the Icahn School of Medicine at Mount Sinai.

7 Jun 2013

Researchers mobilize brain's native stem cells to replenish neuron lost in Huntington's disease

Researchers have been able to mobilize the brain's native stem cells to replenish a type of neuron lost in Huntington's disease.

7 Jun 2013

Researchers build the first-ever bridge between optomechanics and microfluidics

Ever been to a whispering gallery-a quiet, circular space underneath an old cathedral dome that captures and amplifies sounds as quiet as a whisper?

7 Jun 2013

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Cancer cells' appetite for sugar may have serious consequences for immune cell function, researchers at Washington University School of Medicine in St. Louis have learned.

7 Jun 2013

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Scientists at the Danish Stem Cell Center, DanStem, at the University of Copenhagen have discovered that they can make embryonic stem cells regress to a stage of development where they are able to make placenta cells as well as the other fetal cells.

7 Jun 2013

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

Researchers at the JC Self Research Institute of the Greenwood Genetic Center (GGC), along with collaborators from Biolog, Inc. in California, have reported an important discovery in the understanding of autism which was published this week in Molecular Autism.

7 Jun 2013

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

A recent article in the New England Journal of Medicine describes genetic testing of a rare blood cancer called atypical chronic neutrophilic leukemia (CNL) that revealed a new mutation present in most patients with the disease.

7 Jun 2013

Doctors create bioengineered blood vessel and implant it in the arm of kidney disease patient

In a first-of-its-kind operation in the United States, a team of doctors at Duke University Hospital helped create a bioengineered blood vessel and implanted it into the arm of a patient with end-stage kidney disease.

7 Jun 2013

Human Argonautes directly cuts messenger RNA

Human Argonautes (hAgo), are key proteins involved in a process known as RNA interference. RNAi, as it is often called, is a mechanism that cells use to regulate gene expression.

7 Jun 2013

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

The drug ingenol mebutate (trade name: Picato) has been approved in Germany since November 2012 as a gel for the treatment of certain forms of actinic keratosis in adults. In an early benefit assessment pursuant to the Act on the Reform of the Market for Medicinal Products (AMNOG) the German Institute for Quality and Efficiency in Health Care (IQWiG) examined whether this new drug offers an added benefit over diclofenac/hyaluronic acid gel. Such an added benefit cannot be derived from the dossier, however, as the drug manufacturer did not submit any relevant data: it did not cite any studies that directly compared ingenol mebutate with diclofenac/hyaluronic acid gel, and the method chosen by the manufacturer for an indirect comparison was unsuitable.

7 Jun 2013

Cow antibodies points to new ways for making human medicines

Humans have been raising cows for their meat, hides and milk for millennia. Now it appears that the cow immune system also has something to offer. A new study led by scientists from The Scripps Research Institute (TSRI) focusing on an extraordinary family of cow antibodies points to new ways to make human medicines.

7 Jun 2013

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Researchers at the University of California, San Diego School of Medicine and colleagues report that the herpes simplex virus type-1 (HSV-1), which affects an estimated 50 to 80 percent of all American adults, exploits an immune system receptor to boost its infectivity and ability to cause disease.

7 Jun 2013

Researchers demonstrate how young genes acquire essential functions

Researchers from UConn and other institutions in the U.S. and abroad have shown how a relatively young gene can acquire a new function and become essential to an organism's life.

7 Jun 2013

Researchers define nine molecular hallmarks of aging, debunk myths related to antioxidants

For some species, living twice as long in good health depends on no more than a few genes. When this fact was revealed by studies on worms three decades ago, it ushered in a golden age of ageing studies that has delivered numerous results, but also sown some confusion.

7 Jun 2013

Changes in normal glycan behavior lead to fatal lysosomal disease, say researchers

From the neurons that enable thought to the keratinocytes that make toenails grow-a complex canopy of sugar molecules, commonly known as glycans, envelop every living cell in the human body.

6 Jun 2013

Communications aimed at shifting organizational culture can overcome gender differences in career paths

To attract and maintain a diverse, qualified academic workforce, institutions of higher education should have - and promote - policies to help balance career and family life, according to an article published by UC Davis researchers in the June 2013 issue of Academic Medicine.

6 Jun 2013

Research reveals how HIV triggers signal to kill infected immune cell

Untreated HIV infection destroys a person's immune system by killing infection-fighting cells, but precisely when and how HIV wreaks this destruction has been a mystery until now. New research by scientists at the National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, reveals how HIV triggers a signal telling an infected immune cell to die.

6 Jun 2013

Inflection Biosciences signs license agreement with CNIO to develop kinase inhibitors for cancer treatment

Inflection Biosciences Ltd, a private company focused on the development of targeted small molecule treatments for cancer, today announced that it has entered into a license agreement with the Spanish National Cancer Research Centre (CNIO) for the exclusive, worldwide rights to develop and commercialise several novel kinase inhibitors for the treatment of cancer.

6 Jun 2013

Researchers discover TRF1 gene that is important for nuclear reprogramming

Researchers are still fascinated by the idea of the possibility of reprogramming the cells of any tissue, turning them into cells with the capacity to differentiate into cells of a completely different type- pluripotent cells-and they are still striving to understand how it happens.

6 Jun 2013

BioLineRx starts enrollment in Phase 2 trial of BL-8040 for treatment of AML

BioLineRx, a biopharmaceutical development company, announced today enrollment of the first patient in a Phase 2 trial for BL-8040, for the treatment of acute myeloid leukemia.

6 Jun 2013

Cell News and Research

New gene variant found in human and animal tissue offers a promising treatment for cancer

Researchers mobilize brain's native stem cells to replenish neuron lost in Huntington's disease

Researchers build the first-ever bridge between optomechanics and microfluidics

Cancer cells' appetite for sugar may have serious consequences for immune cell function

Rewinding the developmental state of embryonic stem cells is possible, say researchers

Study: Individuals with ASDs show decrease metabolism of amino acid L-tryptophan

Genetic testing of chronic neutrophilic leukemia reveals presence of new mutation in patients

Doctors create bioengineered blood vessel and implant it in the arm of kidney disease patient

Human Argonautes directly cuts messenger RNA

Ingenol mebutate drug does not offer added benefit over diclofenac/hyaluronic acid gel

Cow antibodies points to new ways for making human medicines

HSV-1 exploits immune system receptor to boost infectivity and cause disease

Researchers demonstrate how young genes acquire essential functions

Researchers define nine molecular hallmarks of aging, debunk myths related to antioxidants

Changes in normal glycan behavior lead to fatal lysosomal disease, say researchers

Communications aimed at shifting organizational culture can overcome gender differences in career paths

Research reveals how HIV triggers signal to kill infected immune cell

Inflection Biosciences signs license agreement with CNIO to develop kinase inhibitors for cancer treatment

Researchers discover TRF1 gene that is important for nuclear reprogramming

BioLineRx starts enrollment in Phase 2 trial of BL-8040 for treatment of AML

How to optimize your cell line development eBook

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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