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New drug zilebesiran effectively lowers blood pressure for six months, study finds

A single injection of the experimental medication zilebesiran was safe and effective in reducing systolic blood pressure in people with mild-to-moderate high blood pressure for up to six months, as detailed in the Phase 2 of the KARDIA study, reported as late-breaking science today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

A National Institutes of Health-supported study found that the type of transfusion approach used to support adults who developed anemia after a heart attack did not make a significant difference in their likelihood of having another heart attack or dying within 30 days.

13 Nov 2023

Researchers improve the system for stratifying mortality risk of variceal bleeding

Approximately half of patients with advanced liver disease have varicose veins in the esophagus and stomach, and a more than a fifth of them experience bleeding from these varices into the digestive tract.

13 Nov 2023

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

A single infusion of a CRISPR-based gene-editing therapy significantly reduced low-density lipoprotein cholesterol (LDL, the "bad cholesterol") in people who carry one gene for the inherited condition that results in very high LDL cholesterol levels and a high risk of heart attack at an early age, according to late-breaking science presented today at the American Heart Association's Scientific Sessions 2023.

13 Nov 2023

NanoSyrinx appoints Anthony Johnson as Non-Executive Director

Appointment of Big Pharma executive strengthens leadership team to drive ambitious growth strategy.

From NanoSyrinx 13 Nov 2023

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

Findings from a multi-center, international clinical trial reported by a Cleveland Clinic physician show that semaglutide reduced cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease who do not have diabetes.

13 Nov 2023

AdvanCell reaches milestone as first prostate cancer patient dosed with 212Pb-ADVC001

AdvanCell, a radiopharmaceutical company developing a pipeline of Targeted Alpha Therapies for cancer patients, today announced the first patient was treated with 212Pb-ADVC001, a Targeted Alpha Therapy in development for the treatment of PSMA-positive metastatic Castration-Resistant Prostate Cancer (mCRPC).

13 Nov 2023

UK regulator approves a diabetes drug for weight management in obese and overweight patients

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (8 November 2023) authorised via a national application route, a new indication for the diabetes medicine, Mounjaro (tirzepatide), for weight loss and weight management in adults aged 18 and over.

13 Nov 2023

Food allergies may be linked to increased cardiovascular death risk, study finds

Sensitivity to common food allergens such as dairy and peanuts could be an important and previously unappreciated cause of heart disease, new research suggests – and the increased risk for cardiovascular death includes people without obvious food allergies.

13 Nov 2023

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

As a founding member and former chair of the International Coalition of Medicines Regulatory Authorities (ICMRA), the Medicines and Healthcare products Regulatory Agency (MHRA) is joining global partners in celebrating ten years of strategic leadership and cooperation.

13 Nov 2023

Liberal blood transfusion may reduce recurrence risk, improve survival in heart attack patients with anemia

An international clinical trial led by physician Jeffrey L. Carson, distinguished professor of medicine at Rutgers Robert Wood Johnson Medical School, found that a liberal blood transfusion given to patients who have had a heart attack and have anemia may reduce the risk of a reoccurrence and improve survival rates.

12 Nov 2023

UCI researchers discover gene critical for muscle repair

University of California, Irvine researchers have identified a gene expressed during regeneration that is critical for muscle repair.

12 Nov 2023

Maternal metabolic conditions linked to children's neurodevelopmental risks, study shows

Study investigates how maternal metabolic conditions like pregestational diabetes, gestational diabetes, and obesity mediate the risk of neurodevelopmental conditions in children. It highlights the significant role of obstetric and neonatal complications in this relationship, emphasizing the need for managing these complications to mitigate children's risk of developing conditions like ADHD and autism.

12 Nov 2023

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

A recent study in the journal BMC Medicine evaluates the real-world impact of combining antidepressants with statins in UK adults, revealing lower discontinuation rates but similar efficacy compared to antidepressant-only treatment.

12 Nov 2023

Lowering sodium intake can help reduce blood pressure

Nearly everyone can lower their blood pressure, even people currently on blood pressure-reducing drugs, by lowering their sodium intake, reports a new study from Northwestern Medicine, Vanderbilt University Medical Center and the University of Alabama at Birmingham.

11 Nov 2023

Mini-summit to address how informatics can help resolve health effects of climate change

Regenstrief Institute, the International Medical Informatics Association (IMIA), the International Academy of Health Sciences Informatics (IAHSI) and the American Medical Informatics Association (AMIA) are hosting a mini-summit at the AMIA 2023 Annual Symposium to address how informatics can help resolve health issues caused by climate change.

10 Nov 2023

Preclinical research points to a promising new treatment option for pancreatic cancer patients

Preclinical research published in the Journal for ImmunoTherapy of Cancer points to a promising new treatment option for people with pancreatic cancer.

10 Nov 2023

NCI grants $5 million to UTHealth Houston for cancer control research in Mexico and Latin America

A five-year, $5 million grant has been awarded by the National Cancer Institute (NCI) to the UTHealth Houston Institute for Implementation Science to support research and training in implementation science, with a focus on improving cancer control efforts in Mexico and Latin America.

10 Nov 2023

Bath student engineers win international competition to design an artificial heart

Student engineers from the University of Bath are on top of the world after winning an international competition to design an artificial heart.

10 Nov 2023

One in six patients with coronary artery disease found to have non-ischemic or dual cardiomyopathy

Researchers from the University of Minnesota Medical School examining the cause of cardiomyopathy discovered one out of every six patients with coronary artery disease had non-ischemic or dual cardiomyopathy.

10 Nov 2023

Medicine News and Research

New drug zilebesiran effectively lowers blood pressure for six months, study finds

Researchers encourage flexible approach to blood transfusion decisions for heart attack patients with anemia

Researchers improve the system for stratifying mortality risk of variceal bleeding

CRISPR-based gene-editing therapy could offer hope for people with inherited high LDL cholesterol

NanoSyrinx appoints Anthony Johnson as Non-Executive Director

SELECT trial: Semaglutide reduces cardiovascular events by 20% in overweight or obese patients without diabetes

AdvanCell reaches milestone as first prostate cancer patient dosed with 212Pb-ADVC001

UK regulator approves a diabetes drug for weight management in obese and overweight patients

Food allergies may be linked to increased cardiovascular death risk, study finds

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

Liberal blood transfusion may reduce recurrence risk, improve survival in heart attack patients with anemia

UCI researchers discover gene critical for muscle repair

Maternal metabolic conditions linked to children's neurodevelopmental risks, study shows

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

Lowering sodium intake can help reduce blood pressure

Mini-summit to address how informatics can help resolve health effects of climate change

Preclinical research points to a promising new treatment option for pancreatic cancer patients

NCI grants $5 million to UTHealth Houston for cancer control research in Mexico and Latin America

Bath student engineers win international competition to design an artificial heart

One in six patients with coronary artery disease found to have non-ischemic or dual cardiomyopathy

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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