Assay News and Research

RSS

Amplified Sciences secures $400,000 grant to develop pancreatic cancer diagnostic test

Health care providers and their patients could know with greater confidence whether pancreatic cysts are benign or potentially malignant, and if surgery is required to remove them, by using a new diagnostic test currently in development.

12 Jul 2023

How does SARS-CoV-2 affect the placenta during pregnancy?

Researchers examine host responses to SARS-CoV-2 within the placenta using transcriptomics.

12 Jul 2023

Study investigates the antioxidant activity of hemp leaves

Researchers explored the antioxidant potential and extraction efficiency of active compounds from hemp leaves using different solvents and mixtures.

11 Jul 2023

mAb-based bELISA developed to detect SARS-CoV-2 antibodies in a broad spectrum of animal species

Researchers developed a mAb-based blocking enzyme-linked immunosorbent assay (bELISA) to detect SARS-CoV-2 in animals.

11 Jul 2023

Novel vaccine against Lyme disease reported to be safe and effective

Researchers determine the safety and immunogenicity of a novel candidate vaccine against Lyme borreliosis.

11 Jul 2023

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

The Association for Molecular Pathology (AMP), the premier global molecular diagnostic professional society, today published consensus recommendations to aid in the design and validation of clinical CYP3A4 and CYP3A5 genotyping assays, promote standardization of testing across different laboratories, and improve patient care.

10 Jul 2023

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Persistent immune activation and elevated cytokine levels were observed in patients with severe COVID-19, even months after recovery. However, the correlation between immune activation and long COVID symptoms appeared to be independent, suggesting other factors influencing disease severity.

9 Jul 2023

Scientists develop cross-species coronavirus test

In an advance that will help scientists track coronavirus variants in wild and domesticated animals, researchers report they can now detect exposure to the SARS-CoV-2 virus in any animal species.

6 Jul 2023

Rising incidence of kiwifruit allergy in children: study highlights severe allergic reactions

Study aimed to compile Kiwifruit allergy recognition patterns to enhance patient management and clinical practice.

6 Jul 2023

Dengue outbreak overlapped COVID-19 crisis in Key Largo, Florida in 2020: Call for enhanced disease testing protocols

Detection and response to a dengue outbreak in Florida during the COVID-19 pandemic in 2020, highlighting the challenges of diagnosing febrile illnesses and the need for surveillance. This study examines the impact and management of dengue cases in the context of the ongoing pandemic.

5 Jul 2023

A novel RSV vaccine that could be effective across all ages

Researchers evaluate the in vivo efficacy of a respiratory syncytial virus vaccine in old and young rats.

4 Jul 2023

SYS6006 investigational COVID-19 mRNA vaccine shows promise as fourth dose booster

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 600 million confirmed cases and 6.5 million deaths worldwide.

4 Jul 2023

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

Activation of the NRF2 transcription factor shows promise as a potential treatment approach for non-alcoholic fatty liver disease (NAFLD), a condition associated with oxidative stress and liver damage. By screening FDA-approved drugs, researchers identified six compounds that enhanced NRF2 activity and demonstrated protective effects against oxidative stress and lipid accumulation.

3 Jul 2023

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

Formononetin (FNT), an isoflavonoid present in beer, was investigated for its effects on chondrocytes, the cells responsible for joint health. While low levels of FNT showed no harm and reduced inflammation, excessive exposure promoted catabolic responses, shedding light on the relationship between beer consumption and osteoarthritis risk.

3 Jul 2023

New COVID-19 mRNA vaccine is safe and highly immunogenic as a heterologous booster: Study

The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has resulted in more than 600 million confirmed cases and 6.5 million deaths worldwide.

3 Jul 2023

COVID-19 severity linked to autoantibodies against blood clotting protein

Study investigates the occurrence of ADAMTS13 antibodies in COVID-19 patients and their association with disease severity and lower ADAMTS13 activity. The findings suggest the need to include ADAMTS13 antibodies in diagnosing and managing SARS-CoV-2 infections.

2 Jul 2023

Towards Zika preparedness: immunogenicity insights from vaccine research

Study assesses the safety and immunogenicity of an inactivated Zika virus vaccine candidate.

30 Jun 2023

Study shows promising prospects for automating 3D-DSRT in drug testing

The June 2023 issue of SLAS Discovery contains one review article, five full-length articles and two technical briefs covering spheroid models, 3D cell high-throughput screening (HTS) applications for treating Alzheimer's and other drug discovery research.

29 Jun 2023

UH and CWRU research teams win Collaborative Science Pilot Awards

Three University Hospitals (UH) and Case Western Reserve University School of Medicine research teams recently received Collaborative Science Pilot Awards. The teams each received $50,000, funded by both institutions.

28 Jun 2023

New digital assay can directly measure the presence of HIV in single drop of blood

A milliliter of blood contains about 15 individual drops. For a person with human immunodeficiency virus (HIV), each drop of blood could contain anywhere from fewer than 20 copies of the virus to more than 500,000 copies.

27 Jun 2023

Assay News and Research

Amplified Sciences secures $400,000 grant to develop pancreatic cancer diagnostic test

How does SARS-CoV-2 affect the placenta during pregnancy?

Study investigates the antioxidant activity of hemp leaves

mAb-based bELISA developed to detect SARS-CoV-2 antibodies in a broad spectrum of animal species

Novel vaccine against Lyme disease reported to be safe and effective

AMP releases consensus recommendations for CYP3A4 and CYP3A5 genotyping assays

Prolonged T-cell response during severe COVID-19 does not contribute to long COVID

Scientists develop cross-species coronavirus test

Rising incidence of kiwifruit allergy in children: study highlights severe allergic reactions

Dengue outbreak overlapped COVID-19 crisis in Key Largo, Florida in 2020: Call for enhanced disease testing protocols

A novel RSV vaccine that could be effective across all ages

SYS6006 investigational COVID-19 mRNA vaccine shows promise as fourth dose booster

CRISPR/Cas9-based screening identifies potential therapies for non-alcoholic fatty liver disease

New study uncovers effects of beer compound on cartilage cells in osteoarthritis

New COVID-19 mRNA vaccine is safe and highly immunogenic as a heterologous booster: Study

COVID-19 severity linked to autoantibodies against blood clotting protein

Towards Zika preparedness: immunogenicity insights from vaccine research

Study shows promising prospects for automating 3D-DSRT in drug testing

UH and CWRU research teams win Collaborative Science Pilot Awards

New digital assay can directly measure the presence of HIV in single drop of blood

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

Latest News