Birth Defects News and Research

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GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Among scientists specializing in the area, the mechanisms behind the signaling function of the Hedgehog (Hh) receptor pathway remain a mystery. Xiaoyen Zheng, Ph.D., assistant professor of anatomy and regenerative biology at the George Washington University School of Medicine and Health Sciences, who recently received a $1.7 million grant from the National Institutes of Health and National Institute of General Medical Sciences, is determined to learn more about the Hh pathway.

4 May 2017

Computational analysis highlights potential economic burden of Zika outbreak in the U.S.

Even a relatively mild Zika outbreak in the United States could cost more than $183 million in medical costs and productivity losses, suggests a computational analysis led by Johns Hopkins Bloomberg School of Public Health researchers, while a more severe one could result in $1.2 billion or more in medical costs and productivity losses.

3 May 2017

Study reveals safety data for using antimalarials during first trimester of pregnancy

Malaria is more common and severe in pregnant women, increasing their risk of miscarriage and other adverse outcomes. The adverse consequences of malaria in pregnancy require prompt, safe, and effective treatment.

3 May 2017

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Using the new gene-editing enzyme CRISPR-Cpf1, researchers at UT Southwestern Medical Center have successfully corrected Duchenne muscular dystrophy in human cells and mice in the lab.

13 Apr 2017

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

Zika virus is a mosquito-borne infectious disease linked to certain birth defects in infants in South and Central America and the United States.

11 Apr 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

Scientists shed light on evolutionary arms race between CMV and immune system

Imaging CoE scientists have solved a 40-year old mystery and shed light on an evolutionary arms race played out between cytomegalovirus (CMV) and the immune system.

10 Apr 2017

Researchers discover small protein essential for formation of skeletal muscle

UT Southwestern Medical Center researchers discovered a small protein named Myomixer essential for the formation of skeletal muscle – findings that could eventually help treat genetic diseases such as muscular dystrophy and other myopathies.

7 Apr 2017

Health officials increase prevention efforts to address serious threats of Zika virus

State and territorial health officials are redoubling prevention efforts to address the serious public health threats associated with Zika virus and to protect the health of mothers and babies.

6 Apr 2017

Study reveals that 25% of women with prenatal opioid addiction are not being treated

A new study by Queen's University researcher Susan Brogly (Surgery) has revealed that 25 per cent of women suffering from a prenatal opioid dependence were not being treated for their addiction.

5 Apr 2017

Zika-related birth defects reported by 1 in 10 US based pregnant women infected by the virus in 2016

The new Vital Signs report, released by the Centers for Disease Control and Prevention (CDC), has reported that of 250 pregnant women confirmed with Zika infection in 2016, approximately 1 in 10 of them had a fetus or infant with virus-related birth defects. Thisreport is the first of its kind, to present an analysis from a sample of US women with a definite case of Zika infection during pregnancy.

5 Apr 2017

Mother's alcohol misuse before conception may have lifelong negative effects on offspring

Mothers who binge drink before they become pregnant may be more likely to have children with high blood sugar and other changes in glucose function that increase their risk of developing diabetes as adults, according to a new study conducted in rats.

3 Apr 2017

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Vaccinations have begun in a multi-site Phase 2/2b clinical trial testing an experimental DNA vaccine designed to protect against disease caused by Zika infection.

31 Mar 2017

Researchers map key Zika virus protein to accelerate search for cure

A study published today shows how Indiana University scientists are speeding the path to new treatments for the Zika virus, an infectious disease linked to birth defects in infants in South and Central America and the United States.

28 Mar 2017

SLU researchers predict potential high-risk areas for Zika virus transmission in the U.S.

Where in the continental United States is Zika most likely to occur? An early online article in the American Journal of Public Health by Saint Louis University researchers puts the bulls-eye of Zika transmission on the Mississippi delta.

27 Mar 2017

Researchers describe set of observable characteristics linked to congenital Zika syndrome

Even as the Zika virus becomes more prevalent — the Centers for Disease Control reports that the number of U.S. infants born with microcephaly and other birth defects is 20 times over the normal rate — researchers are still trying to fully pin down the identifying consequences of the viral infection.

24 Mar 2017

Birth Defects News and Research

GW scientist awarded $1.7 million grant to understand mechanisms behind Hedgehog receptor

Computational analysis highlights potential economic burden of Zika outbreak in the U.S.

Study reveals safety data for using antimalarials during first trimester of pregnancy

Researchers correct Duchenne muscular dystrophy using gene-editing alternative

Scientists solve structure of protein crucial to reproduction and spread of Zika virus

New study finds link between neural tube defects in infants and neurodegenerative diseases

Scientists shed light on evolutionary arms race between CMV and immune system

Researchers discover small protein essential for formation of skeletal muscle

Health officials increase prevention efforts to address serious threats of Zika virus

Study reveals that 25% of women with prenatal opioid addiction are not being treated

Zika-related birth defects reported by 1 in 10 US based pregnant women infected by the virus in 2016

Mother's alcohol misuse before conception may have lifelong negative effects on offspring

Phase 2 clinical study of investigational Zika vaccine begins in the U.S., Central and South America

Researchers map key Zika virus protein to accelerate search for cure

SLU researchers predict potential high-risk areas for Zika virus transmission in the U.S.

Researchers describe set of observable characteristics linked to congenital Zika syndrome

Children born to older mothers are at an advantage, report researchers

Canadian scientists join international battle against Zika virus

Natural immune molecule shows protective effect against Zika virus in mouse, monkey models

Computational software that evaluates DNA samples may help in diagnosis, treatment of cancer

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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