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Myc genes play key role in self-renewal of spermatogonial stem cells

Sperm are constantly replenished in the adult male body. Understanding the workings of stem cells responsible for this replenishment is expected to shed light on why male fertility diminishes with age, and possibly lead to new treatments for infertility.

28 Dec 2016

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Tumor suppressors stop healthy cells from becoming cancerous. Researchers from Charité - Universitätsmedizin Berlin, the Medical University of Graz and the German Institute of Human Nutrition in Potsdam-Rehbruecke have found that p53, one of the most important tumor suppressors, accumulates in liver after food withdrawal.

21 Dec 2016

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Diamond Blackfan Anemia (DBA) is a condition that is characterized by a failure of the bone marrow to produce red blood cells, congenital abnormalities, and a predisposition to cancer.

17 Dec 2016

Enzyme that cleaves beta carotene may control testosterone levels

An enzyme that converts the dietary carotenoid beta carotene into vitamin A in the body may also regulate testosterone levels and growth of the prostate, a new study found.

7 Dec 2016

Scientists uncover changes in immediate environment of DNA after fertilization

A team of scientists at the Helmholtz Zentrum München shows changes in the immediate environment of DNA after the ovum and sperm fuse to form the zygote. The results suggest why all conceivable somatic cells can develop from the germ cells. The study has been published in the journal 'Genes and Development'.

6 Dec 2016

Scientists investigate role of mitochondria in Alzheimer's disease pathology

On Nov. 25, 1901, a 51-year-old woman is admitted to a hospital in Frankfurt, Germany, displaying a bizarre constellation of symptoms.

8 Nov 2016

Penn study reveals new sights into how some intestinal cells can withstand chemotherapy and radiation

When treating cancer with chemotherapy and radiation, decisions about dose must walk a fine line between attacking cancerous cells and preserving healthy ones.

31 Oct 2016

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

Even though it's almost impossible to see, computational biophysicist Rommie Amaro is using the Stampede supercomputer at the Texas Advanced Computing Center at The University of Texas at Austin to model the largest atomic level system of the tumor suppression protein p53 to date -- over 1.5 million atoms.

27 Oct 2016

New study provides most comprehensive picture to date of head and neck cancer stem cells

Cancer stem cells resist therapy and are a major cause of relapse, long after the bulk of a tumor has been killed.

15 Sep 2016

Columbia researchers find way to reawaken potent cancer-fighting molecule in tumor cells

A potent cancer-fighting molecule in our cells can be reawakened by reducing levels of a protein - called SET - that's often found in excess in cancer cells, a new study from Columbia University's Herbert Irving Comprehensive Cancer Center has found.

15 Sep 2016

Cold plasma therapy may help treat non-healing wounds

Russian scientists at the Moscow Institute of Physics and Technology, the Joint Institute for High Temperatures of the Russian Academy of Sciences, and Gamaleya Research Centre of Epidemiology and Microbiology found that treating cells with cold plasma leads to their regeneration and rejuvenation.

13 Sep 2016

Researchers reveal how traditional Chinese medicine helps treat various cancers

Researchers at the University of Adelaide have shown how a complex mix of plant compounds derived from ancient clinical practice in China - a Traditional Chinese Medicine - works to kill cancer cells.

8 Sep 2016

Tumor microenvironment acts as source of resistance to cancer therapies

Researchers at Bellvitge Biomedical Research Institute have published a new Oncotarget work which highlights the importance of the tumor environment as a source of resistance to treatment in colorectal cancer, the fourth most common cancer and the leading cause of cancer death worldwide.

7 Sep 2016

Cell Cycle News and Research

Myc genes play key role in self-renewal of spermatogonial stem cells

Researchers find accumulation of tumor suppressor in liver after food withdrawal

Research finds link between p53 pathway and ribosome biogenesis, nucleotide metabolism in DBA

Enzyme that cleaves beta carotene may control testosterone levels

Scientists uncover changes in immediate environment of DNA after fertilization

Scientists investigate role of mitochondria in Alzheimer's disease pathology

Penn study reveals new sights into how some intestinal cells can withstand chemotherapy and radiation

Supercomputer simulations of p53 protein could boost future anti-cancer drug discovery

New study provides most comprehensive picture to date of head and neck cancer stem cells

Columbia researchers find way to reawaken potent cancer-fighting molecule in tumor cells

Cold plasma therapy may help treat non-healing wounds

Researchers reveal how traditional Chinese medicine helps treat various cancers

Tumor microenvironment acts as source of resistance to cancer therapies

Six NIH-funded projects aim to identify biological factors that affect neural regeneration

Scientists move a step closer to translating BubR1 protein's function into potential cancer therapy

Novel dual molecular tuner offers easy way to perform in-depth analyses in mammalian cells

Loss of senescent cells improves pulmonary function in mice

Brazilian study discovers promising therapeutic and diagnostic target for treatment of melanoma

Scientists use Regeneration Intelligence to assess perturbation status of many signaling pathways

Researches create mini-brain model of idiopathic ASD characterized by early neuronal overgrowth

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