Lipoprotein News and Research

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A lipoprotein is a biochemical assembly that contains both proteins and lipids. The lipids or their derivatives may be covalently or non-covalently bound to the proteins.

Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

Researchers have shown how moderate egg consumption can increase the amount of heart-healthy metabolites in the blood, publishing their results today in eLife.

24 May 2022

Ensitrelvir demonstrates swift SARS-CoV-2 clearance and safety among individuals with asymptomatic, mild, or moderate SARS-CoV-2 infections

Researchers reported findings that assessed the safety and efficacy of Ensitrelvir among patients with asymptomatic or mild-to-moderate SARS-CoV-2 infection in Japan.

20 May 2022

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

Health screening and genetic tests might identify more than 1 million U.S. adults who carry a gene for familial hypercholesterolemia, a common genetic disorder that causes elevated low-density lipoprotein (LDL) cholesterol, known as "bad cholesterol," which may lead to premature heart attack or death, according to new research published today in the Journal of the American Heart Association, an open access, peer-reviewed journal of the American Heart Association.

18 May 2022

The potential role of the gut microbiome in modifying patient responses to statin therapy

Researchers discovered strong links between human gut microbiome makeup and statin on- and off-target effects, probably beneficial in medication tailoring.

13 May 2022

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Results from a new mouse model may aid in understanding how depression and prolonged and severe stress increase the risk of cardiovascular disease, according to preliminary research presented at the American Heart Association's Vascular Discovery: From Genes to Medicine Scientific Sessions 2022.

13 May 2022

Hormonal shift during menopause changes women’s blood metabolite profile

In midlife, the risk of cardiometabolic diseases increases in women more rapidly than in men. A study performed at the Faculty of Sport and Health Sciences of the University of Jyväskylä shows that changes in blood metabolite profile accompany the shift in sex hormone levels during menopause.

13 May 2022

Espresso coffee is unhealthier for men than for women

Coffee raises serum cholesterol due to its diterpenes, cafestol and kahweol, and brewing methods have an impact on the level. Studies that assess espresso coffee's effect on serum cholesterol are scarce. This study was conducted to investigate how different brewing methods, particularly espresso, influence serum total cholesterol (S-TC).

11 May 2022

Association between physical activity paradox and risk variables for cardiovascular disease

In a new study, investigators analyzed the significance of the physical activity paradox in the risk variables for cardiovascular disease (CVD).

11 May 2022

Vegan diets can be used in the management of overweight and type 2 diabetes

A 12-week vegan diet may result in clinically meaningful weight loss and improve blood sugar control in overweight adults and those with type 2 diabetes, according to a meta-analysis of 11 randomized trials involving almost 800 participants (aged 18 or older), being presented at this year's European Congress on Obesity (ECO) in Maastricht, Netherlands (4-7 May).

6 May 2022

Effect of vegetarian food intake on nutritional status and growth of young children

In a new study, researchers examined the association between a vegetarian diet and growth, micronutrients, and lipids among healthy children.

4 May 2022

Aspirin for non-obstructive coronary artery disease does not reduce major cardiovascular events

Aspirin therapy, as opposed to statin use, for non-obstructive coronary artery disease does not reduce major cardiovascular events, according to a new study published in the journal Radiology: Cardiothoracic Imaging.

28 Apr 2022

Expanding statin prescription could be a cost-effective intervention against cardiovascular disease

Expanding prescription of statin medication to reduce low-density lipoprotein cholesterol could be a cost-effective intervention against cardiovascular disease, according to a Northwestern Medicine study published in the journal Circulation.

8 Apr 2022

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

Nearly half of heart disease patients have insomnia, according to research presented at ESC Preventive Cardiology 2022, a scientific congress of the European Society of Cardiology, and published in SLEEP Advances.

7 Apr 2022

The association of lipid levels with the risk of COVID-19 infection, hospitalization, disease severity, and mortality

A recent study conducted by a team of international scientists has highlighted that individuals with high serum levels of high-density lipoprotein-cholesterol are less susceptible to SARS-CoV-2 infection.

6 Apr 2022

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Compared with a placebo, the addition of the injectable cholesterol-lowering drug alirocumab to high-intensity statin treatment in patients who have had a heart attack resulted in twofold greater reductions in three key measures of plaque vulnerability that signal risk for future cardiac events, according to research presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

While there are effective therapies to reduce the risk of heart disease by lowering low-density lipoprotein (LDL), or "bad" cholesterol, and other lipids, to date there are no approved treatments to lower lipoprotein(a), a lesser-known driver of heart disease risk.

3 Apr 2022

Investigational drug vupanorsen reduces non-HDL cholesterol by up to 28%

The investigational drug vupanorsen reduced total levels of non-high-density lipoprotein (non-HDL) cholesterol by up to 28% in patients with high cholesterol who were already taking a cholesterol-lowering statin medication, in a study presented at the American College of Cardiology's 71st Annual Scientific Session.

3 Apr 2022

Lipoprotein News and Research

Further Reading

Eating up to one egg per day may help lower cardiovascular disease risk, research suggests

Ensitrelvir demonstrates swift SARS-CoV-2 clearance and safety among individuals with asymptomatic, mild, or moderate SARS-CoV-2 infections

Health screening and genetic tests may help detect people who carry a gene for familial hypercholesterolemia

The potential role of the gut microbiome in modifying patient responses to statin therapy

New mouse model shows the connection between stress, depression and cardiovascular disease risk

Hormonal shift during menopause changes women’s blood metabolite profile

Espresso coffee is unhealthier for men than for women

Association between physical activity paradox and risk variables for cardiovascular disease

Vegan diets can be used in the management of overweight and type 2 diabetes

Effect of vegetarian food intake on nutritional status and growth of young children

Aspirin for non-obstructive coronary artery disease does not reduce major cardiovascular events

Expanding statin prescription could be a cost-effective intervention against cardiovascular disease

Insomnia common in heart disease patients and linked with subsequent cardiovascular events

The association of lipid levels with the risk of COVID-19 infection, hospitalization, disease severity, and mortality

Addition of alirocumab to high-intensity statin treatment reduces key measures of plaque vulnerability

Experimental siRNA therapeutic shows promise to reduce an important driver of heart disease risk

Investigational drug vupanorsen reduces non-HDL cholesterol by up to 28%

Experimental siRNA therapy reduces a key driver of heart disease risk by up to 98%

Higher avocado intake associated with lower risk of cardiovascular disease and coronary heart disease in US adults

UW Medicine scientists contribute to the publication of first complete, gapless genome sequence

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