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New research changes the paradigm of how people think about graft-versus-host disease

New research challenges the prevailing hypothesis for how donor stem cell grafts cause graft-versus-host disease, or GVHD, and offers an alternative model that could guide development of novel therapies.

30 Jan 2023

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Scientists at Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine have illuminated how treatments for multiple myeloma and other aggressive blood cancers can lead to future malignancies, called therapy-related myeloid neoplasms (tMNs).

25 Jan 2023

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

Alcohol-related liver disease is among the most common causes of morbidity and mortality worldwide. Due to an incomplete understanding of the factors contributing to disease development, liver transplantation is still the only available cure.

24 Jan 2023

MedUni Vienna researchers identify specific immune response to Epstein-Barr virus

Medical science has not yet been able to explain why the Epstein-Barr virus triggers infectious mononucleosis (IM) in some people with initial infections and not in others.

19 Jan 2023

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

ABO blood-type compatibility between organ donors and recipients is crucial for safe transplantations. Across the different ABO blood groups, longer wait-times for a kidney transplant are often experienced by patients who have type B blood because it is a less common ABO blood type, resulting in fewer donors.

18 Jan 2023

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

The Stem Cell and Bone Marrow Transplant Program at Cedars-Sinai Cancer was recently recognized with two important hallmarks of quality: official accreditation for CAR T-cell therapy, and a third year in a row ranking among the top adult bone marrow transplant programs in the U.S.

18 Jan 2023

New drug combination may offer better prognosis for children diagnosed with deadly brain cancer

Researchers at the University of Colorado Anschutz Medical Campus have discovered a drug combination that may offer a better prognosis for children diagnosed with MYC amplified Medulloblastoma, an often deadly form of brain cancer.

13 Jan 2023

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Posoleucel, an investigational allogeneic off-the-shelf T-cell therapy that simultaneously targets six different viruses, demonstrated promising antiviral efficacy and safety in a phase II study of patients who had undergone stem cell transplantation to treat their cancer or other blood diseases.

11 Jan 2023

Medicare policy change may lead to increased inequities in access to heart transplants

A change to Medicare policy surrounding heart transplant may lead to increased inequities in access to transplant for patients with heart failure, a Michigan Medicine study finds.

11 Jan 2023

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

Severe inflammation weakens the body's ability to kill cancerous blood cells in people with acute myeloid leukemia (AML), a new study shows.

11 Jan 2023

New analysis improves the scientific community's understanding of COVID-19 immunity

A new analysis by Cedars-Sinai investigators is furthering the scientific community's understanding of COVID-19 immunity by showing that similar levels of COVID-19 antibodies are reached over an extended period of time in different population groups.

11 Jan 2023

Hair follicle transplants can rejuvenate scars, study finds

In a new study involving three volunteers, skin scars began to behave more like uninjured skin after they were treated with hair follicle transplants.

6 Jan 2023

New method of donor-lung distribution could decrease deaths of candidates on transplant waitlist

A new method of donor-lung distribution is projected to decrease the number of candidate deaths who are on the waitlist for lung transplant, according to a study by Cleveland Clinic and the U.S. Scientific Registry of Transplant Recipients (SRTR) published in The American Journal of Transplantation.

5 Jan 2023

Sugar appears to play a role in polycystic kidney disease, study finds

A study of kidney organoids in a novel lab environment might have downstream implications for the treatment of polycystic kidney disease (PKD), an incurable condition that affects more than 12 million people worldwide.

5 Jan 2023

Incurable liver disease could be reversed with a single drug

Research led by Associate Professor Duc Dong, Ph.D., has shown for the first time that the effects of Alagille syndrome, an incurable genetic disorder that affects the liver, could be reversed with a single drug.

4 Jan 2023

Mouse study identifies potential targets for treating dry eye disease and corneal injury

People with a condition known as dry eye disease are more likely than those with healthy eyes to suffer injuries to their corneas.

2 Jan 2023

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Researchers at UCSF have developed a novel, potentially life-saving approach that may prevent antibodies from triggering immune rejection of engineered therapeutic and transplant cells.

2 Jan 2023

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

The human immune system is a highly complex network of cells, signals, and responses that is tightly regulated to ensure that the body can fight off infection without damaging its own tissues.

28 Dec 2022

Wafer-thin device could drastically alter the course of treatment for Type 1 diabetes

A quarter-sized device created at Houston Methodist could drastically alter the course of treatment for Type 1 diabetes, a chronic condition that impacts millions of Americans and does not have a cure.

27 Dec 2022

An estimated 19 million US adults living with long-COVID

In a recent study published in the journal Clinical Infectious Diseases, a team of researchers examined the risk factors and prevalence and impact of long coronavirus disease (COVID) among a representative sample of adults in the United States (U.S.) and reported that close to 19 million U.S. adults suffer from long COVID.

26 Dec 2022

Transplant News and Research

New research changes the paradigm of how people think about graft-versus-host disease

Scientists illuminate how blood cancer treatments can lead to therapy-related myeloid neoplasms

Researchers uncover new mechanism that plays key role in the progression of alcohol-related liver disease

MedUni Vienna researchers identify specific immune response to Epstein-Barr virus

Genotyping technology may help increase the number of kidney transplantations and reduce wait times

Cedars-Sinai's Stem Cell and Bone Marrow Transplant Program recognized with two major hallmarks of quality

New drug combination may offer better prognosis for children diagnosed with deadly brain cancer

Investigational T-cell therapy shows antiviral efficacy and safety in cancer patients treated with stem cell transplant

Medicare policy change may lead to increased inequities in access to heart transplants

Study reveals how inflammation alters the tumor microenvironment in acute myeloid leukemia

New analysis improves the scientific community's understanding of COVID-19 immunity

Hair follicle transplants can rejuvenate scars, study finds

New method of donor-lung distribution could decrease deaths of candidates on transplant waitlist

Sugar appears to play a role in polycystic kidney disease, study finds

Incurable liver disease could be reversed with a single drug

Mouse study identifies potential targets for treating dry eye disease and corneal injury

Novel approach may prevent antibodies from triggering immune rejection of transplant cells

Alveolar macrophages present as antigens to promote virus-specific CD8+ T cell expansion

Wafer-thin device could drastically alter the course of treatment for Type 1 diabetes

An estimated 19 million US adults living with long-COVID

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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