Immune System News and Research

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Pfizer-BioNTech vaccine shows reduced neutralization potential against SARS-CoV-2 B.1.1.7 spike variant

Researchers in the UK have conducted a study assessing the efficacy of the Pfizer-BioNTech COVID-19 vaccine BNT162b2 against the new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – the agent that causes coronavirus disease 2019 (COVID-19).

21 Jan 2021

Study: Vast majority of U.S. infants may be suffering from gut microbiome deficiency

A new peer-reviewed study reveals that the vast majority of U.S. infants may be suffering from a substantial deficiency in an important bacterium key to breast milk utilization and immune system development, as well as protection against gut pathogens linked to common newborn conditions such as colic and diaper rash.

21 Jan 2021

New drug target valid for breast cancer as well as lymphoma

One more piece of the puzzle has fallen into place behind a new drug whose anti-cancer potential was developed at the University of Alberta and is set to begin human trials this year, thanks to newly published research.

21 Jan 2021

Scientists identify a molecular mechanism that protects the fetus from maternal infection

Researchers at Duke and Mt. Sinai have identified a molecular mechanism that prevents a viral infection during a mother's pregnancy from harming her unborn baby.

21 Jan 2021

Monocytes could be a key player in sarcoidosis pathogenesis, study shows

The cause of the inflammatory lung disease sarcoidosis is unknown.

21 Jan 2021

Systemic lupus erythematosus disproportionately affects ethnic female population

Just over 200,000 Americans suffer from systemic lupus erythematosus, or SLE, a condition in which the body's immune system mistakenly attacks its own healthy tissues, especially joints and skin, a new study shows.

21 Jan 2021

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Adding the arthritis drug tocilizumab to standard care for patients in hospital with severe or critical covid-19 is no better than standard care alone in improving clinical outcomes at 15 days, finds a new trial published by The BMJ today.

20 Jan 2021

Researchers evaluate the accuracy of NEWS2 scoring system for predicting COVID outcomes

In the first systematic large-scale evaluation of the UK National Early Warning Risk Score (NEWS) 2 as a scoring system for predicting severe COVID-19 outcomes in patients, researchers at King's College London have found poor-to-moderate accuracy for identifying patients at risk of being transferred to intensive care units (ICUs) or dying after 14 days of hospitalization.

20 Jan 2021

Eliminating key gene could revive exhausted immune cells to battle solid tumors

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests.

20 Jan 2021

COVID-19 has transformed the world of vaccines

Researchers at GlaxoSmithKline (GSK) in Italy and Belgium say the coronavirus disease 2019 (COVID-19) pandemic is transforming the world of vaccinology by accelerating vaccine development and the availability of powerful technologies.

20 Jan 2021

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Many patients with multiple myeloma, a type of blood cancer, eventually develop resistance to one treatment after another. That's in part because cancer stem cells drive the disease -- cells that continually self-renew. If a therapy can't completely destroy these malignant stem cells, the cancer is likely to keep coming back.

20 Jan 2021

Stanford study identifies a key factor in mental aging

Scientists have identified a key factor in mental aging and shown that it might be prevented or reversed by fixing a glitch in the immune system’s front-line soldiers.

20 Jan 2021

Patients fend for themselves to access highly touted covid antibody treatments

By the time he tested positive for covid-19 on Jan. 12, Gary Herritz was feeling pretty sick. He suspects he was infected a week earlier, during a medical appointment in which he saw health workers who were wearing masks beneath their noses or who had removed them entirely.

20 Jan 2021

Putatively immature dendritic cells may induce robust immune responses in young children

A study by Ludwig-Maximilians-Universitaet (LMU) in Munich researchers shows that putatively immature dendritic cells found in young children are able to induce robust immune responses. The results could lead to improved vaccination protocols.

20 Jan 2021

Immune systems of COVID-19 patients may rely on antibodies from earlier coronaviruses

The results of a study led by Northern Arizona University and the Translational Genomics Research Institute (TGen), an affiliate of City of Hope, suggest the immune systems of people infected with COVID-19 may rely on antibodies created during infections from earlier coronaviruses to help fight the disease.

20 Jan 2021

Memory B cell response to SARS-CoV-2 evolves up to 6 months after infection, study finds

A new study shows that the memory B cell response to SARS-Cov-2 evolves between 1.3 and 6.2 months after infection in a manner that is consistent with antigen persistence.

19 Jan 2021

Study predicts good passive immunotherapy donors to combat COVID-19

A US-based research team determine good candidates for convalescent plasma donations in promoting passive immunity among severely-ill COVID-19 patients.

19 Jan 2021

Gene-cutting system may play second role as a genetic dimmer switch

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a genetic dimmer switch for CRISPR-Cas9 genes.

19 Jan 2021

Scientists develop world's first test to accurately predict mood disorders

University of South Australia scientists have developed the world's first test to accurately predict mood disorders in people, based on the levels of a specific protein found in the brain.

19 Jan 2021

Timing may be critical when administering treatment after brain injury

Researchers from the National Institutes of Health have discovered Jekyll and Hyde immune cells in the brain that ultimately help with brain repair but early after injury can lead to fatal swelling, suggesting that timing may be critical when administering treatment.

18 Jan 2021

Immune System News and Research

Pfizer-BioNTech vaccine shows reduced neutralization potential against SARS-CoV-2 B.1.1.7 spike variant

Study: Vast majority of U.S. infants may be suffering from gut microbiome deficiency

New drug target valid for breast cancer as well as lymphoma

Scientists identify a molecular mechanism that protects the fetus from maternal infection

Monocytes could be a key player in sarcoidosis pathogenesis, study shows

Systemic lupus erythematosus disproportionately affects ethnic female population

Arthritis drug is no better than standard care in improving severe COVID-19 outcomes, shows new trial

Researchers evaluate the accuracy of NEWS2 scoring system for predicting COVID outcomes

Eliminating key gene could revive exhausted immune cells to battle solid tumors

COVID-19 has transformed the world of vaccines

Designer DNA agent reduces myeloma stem cell abundance, lowers disease burden in mice

Stanford study identifies a key factor in mental aging

Patients fend for themselves to access highly touted covid antibody treatments

Putatively immature dendritic cells may induce robust immune responses in young children

Immune systems of COVID-19 patients may rely on antibodies from earlier coronaviruses

Memory B cell response to SARS-CoV-2 evolves up to 6 months after infection, study finds

Study predicts good passive immunotherapy donors to combat COVID-19

Gene-cutting system may play second role as a genetic dimmer switch

Scientists develop world's first test to accurately predict mood disorders

Timing may be critical when administering treatment after brain injury

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