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Antibiotic-resistant bacteria found in US wastewater treatment plants

Researchers have found methicillin-resistant Staphylococcus aureus in a significant number of wastewater samples taken from four US wastewater treatment plants.

8 Nov 2012

Communications down in anesthetized brain

Two studies indicate that inhaled anesthetics disrupt communication between distant cortical areas before directly activating sleep-inducing neuronal circuitry.

8 Nov 2012

Ocular sebaceous carcinoma rare, but often misdiagnosed in UK

Ocular sebaceous carcinoma is rare in the UK, say researchers in the British Journal of Ophthalmology.

8 Nov 2012

Band counts in infection diagnosis

Even when patients have normal white blood cell counts, elevated band counts may diagnose infection and prompt earlier initiation of antibiotics, report researchers.

8 Nov 2012

Patient recruitment complete for immatics IMA901 Phase 3 trial for renal cell carcinoma

immatics biotechnologies GmbH, a biopharmaceutical company developing rationally designed therapeutic vaccines that are active against cancer, announced today that it has completed patient recruitment into the pivotal phase 3 trial evaluating its lead cancer vaccine IMA901 for renal cell carcinoma (RCC). The trial has completed patient inclusion and it is expected that around 345 patients will be randomized across 10 countries in the US and Europe.

8 Nov 2012

Cardiac arrhythmias: an interview with Dr Andrew Grace

Cardiac arrhythmias are disturbances of the heartbeat. The heart can either go too slowly, which might make people collapse or exhausted; or too quickly.

8 Nov 2012

Autologous stem cells do not improve heart function when given three weeks after heart attack

Administering stem cells derived from patients' own bone marrow either three or seven days after a heart attack is safe but does not improve heart function six months later, according to a clinical trial supported by the National Institutes of Health (NIH).

8 Nov 2012

Researchers simulate activity of cultured neural networks

After a short period of growth, cultured networks of neurons regularly exhibit major activity in the absence of external stimulation. These "bursts" are entirely related to growth. At this stage, they have little to do with learning behaviour, as the network is still too young to sustain a process of memory formation. This has now for the first time been simulated for networks ranging in size from 10,000 to 50,000 neurons. The simulations provide insight into the role of the growth process in initial activity.

8 Nov 2012

Stapled Peptide oncology drug candidate exhibits robust efficacy in xenograft cancer models

Aileron Therapeutics, Inc. and its collaborator Roche today announced new results of a preclinical study of its Stapled Peptide oncology drug candidate ATSP-7041, which exhibited robust efficacy in MDM2 and MDMX xenograft cancer models.

8 Nov 2012

Nanofiber technique to build new nerves from stem cells

Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury.

8 Nov 2012

U-M to improve disease diagnosis through metabolic profiling

The University of Michigan Health System has earned a $9.1 million core grant from the National Institutes of Health to improve disease diagnosis through metabolic profiling.

8 Nov 2012

Two new EU Member States now represented within TRANSVAC services platform

In addition to the initial panel of nine services, the TRANSVAC transnational access platform has integrated in July 2012 five additional groups which provide their services to users on a free and paid basis. Two new European Union (EU) Member States are now represented within the platform of services: France and Portugal.

8 Nov 2012

Carbohydrate-rich food intake may cause recurrence of colon cancer

Colon cancer survivors whose diet is heavy in complex sugars and carbohydrate-rich foods are far more likely to have a recurrence of the disease than are patients who eat a better balance of foods, a new study by Dana-Farber Cancer Institute researchers indicates.

8 Nov 2012

Scientists develop measures to prevent health problems associated with biogenic amines in wine

Biogenic amines may be one of the factors responsible for symptoms such as headaches, gastro-intestinal disorders, shortness of breath, fall in blood pressure, and even unconsciousness and cardiac arrhythmia in severe cases. Histamine, one of the best known members of this group, can cause serious physical problems. Biogenic amines can be produced in the body by natural metabolic activities but are also ingested in larger quantities with food.

8 Nov 2012

New UTSW model can predict progression of skin cancer in patients

UT Southwestern Medical Center scientists led by Dr. Sean Morrison, director of the Children's Medical Center Research Institute at UT Southwestern, have developed an innovative model for predicting the progression of skin cancer in patients.

8 Nov 2012

Researchers discover cellular pathway that causes lung-damaging inflammation in CF

Vancouver researchers have discovered the cellular pathway that causes lung-damaging inflammation in cystic fibrosis (CF), and that reducing the pathway's activity also decreases inflammation.

8 Nov 2012

UC Irvine researchers create new stem cell-derived cell type for treatment of Alzheimer's

UC Irvine researchers have created a new stem cell-derived cell type with unique promise for treating neurodegenerative diseases such as Alzheimer's.

8 Nov 2012

Most prestigious peer-reviewed journals have less influence amongst scientists

The most prestigious peer-reviewed journals in the world, such as Cell, Nature, Science, and the Journal of the American Medical Association (JAMA), have less and less influence amongst scientists, according to a paper co-authored by Vincent Larivière, a professor at the University of Montreal's School of Library and Information Sciences.

7 Nov 2012

Blind people’s brain can learn to process visual input with sounds

Areas of the brain in blind people can learn to process visual input through the use of sound, even after years or perhaps even lifelong blindness, according to new research reported in the November issue of the Cell Press journal Neuron. The findings challenge the common belief that if the visual cortex of the brain is deprived of information in early life, it may never develop functional specialization.

7 Nov 2012

Atpif1 gene regulates hemoglobin synthesis during red blood cell formation

Researchers at Brigham and Women's Hospital (BWH) have discovered a new gene that regulates hemoglobin synthesis during red blood cell formation. The findings advance the biomedical community's understanding and treatment of human anemias and mitochondrial disorders.

7 Nov 2012