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STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

A study in The Journal of Cell Biology shows how a transcription factor called STAT3 remains in the axon of nerve cells to help prevent neurodegeneration. The findings could pave the way for future drug therapies to slow nerve damage in patients with neurodegenerative diseases.

30 Oct 2012

BioXpress, AET BioTech enter agreement to co-develop Adalimumab biosimilar

AET BioTech, the separate biosimilars business within the generic drug developer AET (Alfred E Tiefenbacher) Group and BioXpress Therapeutics SA, a Swiss-based biotechnology company developing monoclonal antibody (MAb) biosimilars have entered into an agreement for the co-development of a biosimilar version of the TNF inhibitor MAb Adalimumab.

30 Oct 2012

Internet, smartphone apps represent prime venues for adolescent-targeted sexual health programs

The use of smartphones is associated with an increased likelihood of being solicited for sex on the internet, and having sex with an internet-met partner among teens, according to new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif.

30 Oct 2012

Sprint Bioscience, TPP partner to develop small molecule inhibitors of choline kinase for cancer

TPP Global Development Ltd (TPP) enters into a collaboration with Sprint Bioscience AB to develop small molecule inhibitors of choline kinase as human therapeutics for the treatment of cancer.

30 Oct 2012

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

New insight into the aggressive behavior of certain adult B-acute lymphoblastic leukemias has provided researchers with a potential new prognostic biomarker and a promising new therapeutic target.

30 Oct 2012

IPSCs may be a viable source of patient-specific articular cartilage tissue

A team of Duke Medicine researchers has engineered cartilage from induced pluripotent stem cells that were successfully grown and sorted for use in tissue repair and studies into cartilage injury and osteoarthritis.

30 Oct 2012

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

30 Oct 2012

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

Array BioPharma Inc. today reported results for the first quarter of its fiscal year ending June 30, 2013.

30 Oct 2012

Four transcription factor genes control processes related to heart and head muscle formation

A group of researchers in Israel, the United States and other nations have made important advances in the rapidly-expanding field of "regenerative medicine," outlining for the first time connections in genetic regulation that normally prevent birth defects in heart and facial muscles.

30 Oct 2012

Variation in size of red cell distribution width is linked with socioeconomic factors

It is well known that socioeconomic factors such as poverty and low education play a role in health, but new research released today at the American Public Health Association's 140th Annual Meeting in San Francisco, Calif., shows this association is also seen in biomarkers of the blood.

30 Oct 2012

Positive results from Celldex’s CDX-1401 Phase 1 study on solid tumors

Celldex Therapeutics, Inc. today announced positive results demonstrating promising clinical effects in a Phase 1 study of CDX-1401 in solid tumors in combination with the toll-like receptor (TLR) agonists resiquimod and/or Poly ICLC.

30 Oct 2012

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

Scientists have discovered a molecular 'tell' in laboratory experiments that could help doctors determine the severity of a patient's prostate cancer.

30 Oct 2012

The PLAN for stroke prognosis

Researchers have developed a new prediction rule, which they say predicts both short-term and 1-year mortality after acute ischemic stroke.

29 Oct 2012

New hope for mitochondrial disease sufferers

Scientists have succeeded in replacing mitochondrial DNA in human oocytes, which they hope will lead to the procedure being developed for use in patients with mitochondrial diseases.

29 Oct 2012

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

A team of national and international researchers, led by Weill Cornell Medical College scientists, have decoded the key "software" instructions that drive three of the most virulent forms of acute lymphoblastic leukemia (ALL). They discovered ALL's "software" is encoded with epigenetic marks, chemical modifications of DNA and surrounding proteins, allowing the research team to identify new potential biomarkers and therapeutic targets.

29 Oct 2012

Botanical treatment holds hope for triple-negative breast cancer

A unique formula made from medicinal mushrooms, traditional Chinese herbs and other natural ingredients inhibits aggressive, human triple-negative breast cancer and breast-to-lung metastasis in mice. This is the third peer-reviewed study to demonstrate the botanical formula's anticancer effects.

29 Oct 2012

Nonclinical data on Provectus PV-10 oncology drug presented at 27th SITC

Provectus Pharmaceuticals, Inc., a development-stage oncology and dermatology biopharmaceutical company, presented nonclinical data on PV-10 at the Society for Immunotherapy of Cancer (SITC) 27th Annual Meeting on October 26 and 27, 2012 in North Bethesda, MD.

29 Oct 2012

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Sea water therapy is a technique of cellular nutrition backed by more than 100 years of clinical use in hospitals, during which numerous studies have demonstrated its beneficial effects on patients' health.

29 Oct 2012

Cellectis announces successful programming of immune system cells to kill cancer cells

Cellectis, the genome engineering specialist, has announced successfully programming cells from the immune system (T cells) to kill cancer cells. This technological breakthrough was revealed for the first time ever on Saturday, October 27th at the congress of the ESGCT (European Society of Gene & Cell Therapy) in Versailles, outside Paris.

29 Oct 2012

Researchers zero in on process by which stem cells maintain proper undifferentiated state

The ability of embryonic stem cells to differentiate into different types of cells with different functions is regulated and maintained by a complex series of chemical interactions, which are not well understood. Learning more about this process could prove useful for stem cell-based therapies down the road. New research from a team led by Carnegie's Yixian Zheng zeroes in on the process by which stem cells maintain their proper undifferentiated state.

29 Oct 2012

Cell News and Research

STAT3 transcription factor remains in the axon of nerve cells to help prevent neurodegeneration

BioXpress, AET BioTech enter agreement to co-develop Adalimumab biosimilar

Internet, smartphone apps represent prime venues for adolescent-targeted sexual health programs

Sprint Bioscience, TPP partner to develop small molecule inhibitors of choline kinase for cancer

Study identifies new prognostic biomarker and therapeutic target for adult B-ALL

IPSCs may be a viable source of patient-specific articular cartilage tissue

Researchers decode software instructions that drive 3 different forms of acute lymphoblastic leukemia

Array BioPharma first quarter 2013 revenue decreases to $15.8 million

Four transcription factor genes control processes related to heart and head muscle formation

Variation in size of red cell distribution width is linked with socioeconomic factors

Positive results from Celldex’s CDX-1401 Phase 1 study on solid tumors

Scientists discover β2-syntrophin protein as new prognosis marker for prostate cancer

The PLAN for stroke prognosis

New hope for mitochondrial disease sufferers

Scientists decode epigenetic programming of three virulent forms of acute lymphoblastic leukemia

Botanical treatment holds hope for triple-negative breast cancer

Nonclinical data on Provectus PV-10 oncology drug presented at 27th SITC

Sea water strengthens the body against viruses, low defences, bacteria and pathogens

Cellectis announces successful programming of immune system cells to kill cancer cells

Researchers zero in on process by which stem cells maintain proper undifferentiated state

How to optimize your cell line development eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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