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Most pediatric hospital physicians communicate through cell phone text messaging

More pediatric hospital physicians are communicating through cell phone text messaging, rather than the traditional pager method, according to research presented Oct. 21 at the American Academy of Pediatrics (AAP) National Conference and Exhibition in New Orleans.

23 Oct 2012

Abbott announces results from HUMIRA clinical studies on ulcerative colitis

Abbott (NYSE: ABT) today announced results from an analysis of three-year long-term data from an ongoing open-label extension of the HUMIRA (adalimumab) ULTRA 1 and ULTRA 2 studies.

23 Oct 2012

Study looks at DNA sequences for receptors in T lymphocytes

Our immune system must be tremendously complex to respond to the unending assault of viruses, bacteria and cancerous cells. One of the mechanisms used by the immune system to cope with the huge variety of possible threats is to randomly combine DNA segments for the production of receptors on lymphocytes - a type of white blood cell.

23 Oct 2012

Blood-circulating monocytes can replace brain resident microglia

The immune system is comprised of multiple cell types each capable of specialized functions to protect the body from invading pathogens and promote tissue repair after injury. One cell type, known as monocytes, circulates throughout the organism in the blood and enters tissues to actively phagocytose (eat!) foreign cells and assist in tissue healing.

23 Oct 2012

Bodyguard macrophages protect stem cells from over-differentiation

Hiding deep inside the bone marrow are special cells. They wait patiently for the hour of need, at which point these blood forming stem cells can proliferate and differentiate into billions of mature blood immune cells to help the body cope with infection, for example, or extra red blood cells for low oxygen levels at high altitudes. Even in emergencies, however, the body keeps to a long-term plan: It maintains a reserve of undifferentiated stem cells for future needs and crises.

23 Oct 2012

Advances in endoscopic technologies and techniques to be highlighted at ACG annual meeting

Advances in endoscopic technologies and techniques will be highlighted in clinical research presented at the 77th Annual Scientific Meeting of the American College of Gastroenterology in Las Vegas, NV.

23 Oct 2012

Protective association between statin use and esophageal cancer

Statins, a cholesterol lowering drug may lower the risk of esophageal cancer, especially in patients with Barrett's esophagus, Mayo Clinic researchers report in a study being presented at the American College of Gastroenterology annual meeting.

23 Oct 2012

Sickle cell disease treatments: An interview with Dr Niihara, CEO of Emmaus Medical

Sickle cell disease is a devastating hereditary condition that affects millions of people, particularly those in West and Central Africa as well as people of African descent in the United States, Europe and South America.

23 Oct 2012

Breast cancer spread dependent on both environment and genetic changes

A new study from Johns Hopkins researchers suggests that the lethal spread of breast cancer is as dependent on a tumor’s protein-rich environment as on genetic changes inside tumor cells.

23 Oct 2012

Exercise may protect the brain from age-related changes

People who exercise later in life may better protect their brain from age-related changes than those who do not, a study suggests.

23 Oct 2012

Glioblastoma multiforme can originate from cortical neurons

Scientists have long believed that glioblastoma multiforme (GBM), the most aggressive type of primary brain tumor, begins in glial cells that make up supportive tissue in the brain or in neural stem cells. In a paper published October 18 in Science Express, however, researchers at the Salk Institute for Biological Studies have found that the tumors can originate from other types of differentiated cells in the nervous system, including cortical neurons.

23 Oct 2012

CSF biomarkers can differentiate patients with Alzheimer's or Parkinson disease

Analysis of specific biomarkers in a cerebrospinal fluid sample can differentiate patients with Alzheimer's disease from those with other types of dementia. The method, which is being studied by researchers at Sahlgrenska Academy, may eventually permit earlier detection of Alzheimer's disease.

23 Oct 2012

Methylation provides clues to gastric cancer subtypes

Research published in Science Translational Medicine shows that many gastric cancers are associated with significant epigenetic alterations along the DNA triggered by methylation.

22 Oct 2012

Thiol peroxidase involved in S. pneumoniae defenses

The Streptococcus pneumoniae bacteria defends itself from high levels of hydrogen peroxide with the help of thiol peroxidase, research shows.

22 Oct 2012

$Ustekinumab success in refractory Crohn’s disease$

Ustekinumab success in refractory Crohn’s disease

Patients with Crohn’s disease who have failed to respond adequately to anti–tumor necrosis factor treatment may benefit from the monoclonal antibody ustekinumab, results of a double-blind, placebo-controlled trial suggest.

22 Oct 2012

PLoS ONE publishes review of AntiViral-HyperActivation Limiting Therapeutics clinical trial

ViroStatics, a private Italian/American biopharmaceutical company developing novel therapeutics for viral and other chronic diseases, announced that a review of the first human clinical trial to test a new class of anti-HIV medications known as AntiViral-HyperActivation Limiting Therapeutics (AV-HALTs) has been published in the peer-reviewed journal PLoS ONE.

22 Oct 2012

Insight into calcium pumps in cells

When animals and plants are exposed to influences such as bacterial attack, odour and cold, calcium ions flow into the cells. The calcium provides the cells with a signal about what is going on outside, but as high concentrations of calcium are toxic to the cells, it must be quickly pumped out again.

22 Oct 2012

Chinese herbs may show significant benefits for patients with NSCLC, IPF and influenza

Chinese herbs, including JHQG, BFXL, and BFHX, may show significant benefits for patients with non-small cell lung cancer (NSCLC), idiopathic pulmonary fibrosis (IPF), and influenza.

22 Oct 2012

VEGF produced by NPCs plays a strong role in influencing microglial behavior

The brain's key "breeder" cells, it turns out, do more than that. They secrete substances that boost the numbers and strength of critical brain-based immune cells believed to play a vital role in brain health. This finding adds a new dimension to our understanding of how resident stem cells and stem cell transplants may improve brain function.

22 Oct 2012

Statin use may improve overall survival and reduce risk of recurrence in resected NSCLC patients

Patients who have undergone resection for non-small cell lung cancer (NSCLC) may improve their overall survival and reduce the risk of recurrence by taking statins.

22 Oct 2012