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Research team identifies turbo switch in the vital calcium pump in our body's cells

A Danish-British research team has discovered a turbo switch in the vital calcium pump in our body's cells. In studies at the X-ray source DORIS at Deutsches Elektronen-Synchrotorn DESY in Hamburg and the European Synchrotron Radiation Facility ESRF in Grenoble the team discovered that the on-off switch of the pump has a previously unknown third position, which switches the pump into a turbo gear.

22 Oct 2012

Closer to engineering new kidney tissue

With a worldwide shortage of kidneys for patients who need kidney transplants, researchers are diligently working to find ways to engineer new kidney tissue from a patient's own cells or another source. They've come a step closer to realizing that goal with a breakthrough described in an upcoming Journal of the American Society of Nephrology (JASN) study.

20 Oct 2012

UCI, Brown work advances quest for novel treatments for inherited disorder

UC Irvine and Brown University researchers have created a new fruit fly model of inherited epilepsy that's providing insights into the mechanisms underlying temperature-dependent seizures while establishing a platform from which to develop therapies for these disorders.

20 Oct 2012

Researchers identify how mosquito's immune system attacks specific infections

Researchers at the Johns Hopkins Bloomberg School of Public Health have determined a new mechanism by which the mosquitoes' immune system can respond with specificity to infections with various pathogens, including the parasite that causes malaria in humans, using one single gene.

20 Oct 2012

Scientists build first atlas of white-matter microstructure in human brain

A European team of scientists have built the first atlas of white-matter microstructure in the human brain. The project's final results have the potential to change the face of neuroscience and medicine over the coming decade.

20 Oct 2012

R848 chemical can prime the immune system to fight lymphoma

UK scientists hope that lymphoma patients could benefit from a new drug that triggers the cancer-fighting properties of the body's own immune system, after highly promising early laboratory results.

From The University of Manchester 20 Oct 2012

Study reveals key chemical process that corrects potential visual errors in low-light conditions

On the road at night or on a tennis court at dusk, the eye can be deceived. Vision is not as sharp as in the light of day, and detecting a bicyclist on the road or a careening tennis ball can be tough.

20 Oct 2012

Dartmouth neurobiologist investigates brain's nerve cells that establish one's location and direction

The Who asked "who are you?" but Dartmouth neurobiologist Jeffrey Taube asks "where are you?" and "where are you going?" Taube is not asking philosophical or theological questions. Rather, he is investigating nerve cells in the brain that function in establishing one's location and direction.

20 Oct 2012

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

By reprogramming skin cells from Parkinson's disease patients with a known genetic mutation, researchers at the Salk Institute for Biological Studies have identified damage to neural stem cells as a powerful player in the disease.

20 Oct 2012

Sortilin receptor plays an important role in function of the immune system

To transport substances from the site of their production to their destination, the body needs a sophisticated transport and sorting system. Various receptors in and on the cells recognize certain molecules, pack them and ensure that they are transported to the right place. One of these receptors is Sortilin.

20 Oct 2012

Reprogrammed vascular endothelial cells from ACs shows promise against vascular disorders

A new approach for generating large numbers of circulatory system cells, known as vascular endothelial cells (VECs), from human amniotic-fluid-derived cells (ACs) is reported in a study published by Cell Press October 18th in the journal Cell. The strategy, which shows promise in mice, opens the door to establishing a vast inventory of VECs for promoting organ regeneration and treating diverse vascular disorders.

20 Oct 2012

Research director at Kessler Foundation awarded NIH grant to study effects of chemotherapy on brain

Guang Yue, PhD, director of Human Performance and Engineering Research at Kessler Foundation, has been awarded a grant by the National Institutes of Health to study the effects of chemotherapy on brain structure, neurophysiology, and psychomotor behavior.

20 Oct 2012

New discovery could help revolutionize antibiotic treatment of bacteria

Three Simon Fraser University scientists are among six researchers who've made a discovery that could help revolutionize antibiotic treatment of deadly bacteria.

20 Oct 2012

Study shows children with low levels of gene activity develop anxious dispositions

Decreased activity of a group of genes may explain why in young children the "fear center" of the anxious brain can't learn to distinguish real threats from the imaginary, according to a new University of Wisconsin study.

20 Oct 2012

Childhood poverty, demographics associated with DNA methylation patterns

A University of British Columbia and Centre for Molecular Medicine and Therapeutics (CMMT) study has revealed that childhood poverty, stress as an adult, and demographics such as age, sex and ethnicity, all leave an imprint on a person's genes. And, that this imprint could play a role in our immune response.

20 Oct 2012

New study decodes complete epigenome of chronic lymphocytic leukemia

Researchers of the University of Oviedo have contributed to decipher the first epigenomes of chronic lymphocytic leukemia.

20 Oct 2012

Study describes design and effectiveness of NIR responsive gold nanorods for chemotherapy

Excitement around the potential for targeted nanoparticles (NPs) that can be controlled by stimulus outside of the body for cancer therapy has been growing over the past few years. More specifically, there has been considerable attention around near-infrared (NIR) light as an ideal method to stimulate nanoparticles from outside the body.

19 Oct 2012

Reprogrammed endothelial cells for treatment of vascular disorders

A research team at Weill Cornell Medical College has discovered a way to utilize diagnostic prenatal amniocentesis cells, reprogramming them into abundant and stable endothelial cells capable of regenerating damaged blood vessels and repairing injured organs.

19 Oct 2012

ACT TIL therapy effective in treating metastatic melanoma

Researchers at Moffitt Cancer Center have carried out a clinical trial in which patients with metastatic melanoma were given chemotherapy and an immunotherapy of adoptive cell transfer (ACT) with tumor infiltrating lymphocytes (TIL).

19 Oct 2012

Babies born to HIV positive mothers more likely to acquire measles

Non-infected babies born to HIV positive mothers should be vaccinated early against measles, to avoid them acquiring the virus or passing it on to others.

19 Oct 2012

Cell News and Research

Research team identifies turbo switch in the vital calcium pump in our body's cells

Closer to engineering new kidney tissue

UCI, Brown work advances quest for novel treatments for inherited disorder

Researchers identify how mosquito's immune system attacks specific infections

Scientists build first atlas of white-matter microstructure in human brain

R848 chemical can prime the immune system to fight lymphoma

Study reveals key chemical process that corrects potential visual errors in low-light conditions

Dartmouth neurobiologist investigates brain's nerve cells that establish one's location and direction

Stem cell study may help to unravel how genetic mutation leads to Parkinson's symptoms

Sortilin receptor plays an important role in function of the immune system

Reprogrammed vascular endothelial cells from ACs shows promise against vascular disorders

Research director at Kessler Foundation awarded NIH grant to study effects of chemotherapy on brain

New discovery could help revolutionize antibiotic treatment of bacteria

Study shows children with low levels of gene activity develop anxious dispositions

Childhood poverty, demographics associated with DNA methylation patterns

New study decodes complete epigenome of chronic lymphocytic leukemia

Study describes design and effectiveness of NIR responsive gold nanorods for chemotherapy

Reprogrammed endothelial cells for treatment of vascular disorders

ACT TIL therapy effective in treating metastatic melanoma

Babies born to HIV positive mothers more likely to acquire measles

How to optimize your cell line development eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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