Biopsy News and Research

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Biopsy is the removal of cells or tissues for examination by a pathologist. The pathologist may study the tissue under a microscope or perform other tests on the cells or tissue. There are many different types of biopsy procedures. The most common types include: (1) incisional biopsy, in which only a sample of tissue is removed; (2) excisional biopsy, in which an entire lump or suspicious area is removed; and (3) needle biopsy, in which a sample of tissue or fluid is removed with a needle. When a wide needle is used, the procedure is called a core biopsy. When a thin needle is used, the procedure is called a fine-needle aspiration biopsy.

Trial shows safety and immunogenicity of immunotherapy with chemoradiation in cervical cancer patients

A Phase I/Ib trial conducted by the National Cancer Institute (NCI) National Clinical Trials Network (NCTN) group NRG Oncology, NRG-GY017, concluded that the addition of the immunotherapy drug atezolizumab prior to and concurrently given with chemoradiation (CRT) treatment was safe for women with node-positive, locally advanced cervical cancer.

19 Mar 2022

New approach radically increases the success of breast cancer immunotherapy

A study published in the journal Nature Cancer, carried out within the Cancer Programme at the Hospital del Mar Medical Research Institute (IMIM-Hospital del Mar) by the Cancer Stem Cells and Metastasis Dynamics Laboratory, led by Dr. Toni Celià-Terrassa, and the Laboratory of Molecular Cancer Therapy, coordinated by Dr. Joan Albanell, with the participation of international centers, has discovered an approach that radically increases the success of immunotherapy in one of the most aggressive types of tumors, triple-negative breast cancer.

17 Mar 2022

Siemens Healthineers launches Enhanced Liver Fibrosis (ELF) Test in the U.S.

The Enhanced Liver Fibrosis (ELF) Test from Siemens Healthineers is now available in the United States, providing broad clinical access to the minimally invasive prognostic tool.

From Siemens Healthineers Laboratory Diagnostics 17 Mar 2022

Placenta found to demonstrate anti-oxidant activity against COVID-19 in full-term pregnancy

Researchers assessed the placental anti-oxidant response in the third trimester of pregnancy against SARS-CoV-2 infections.

16 Mar 2022

Skin biopsy can aid in early identification and differential diagnosis of Parkinson's disease

The diagnosis of Parkinson's disease (PD) is currently based on consensus clinical criteria. A novel study reported in the Journal of Parkinson's Disease has found that the presence of neuronal deposits of the biomarker phosphorylated alpha-synuclein (p-syn) in the brain and the skin of patients with PD distinguishes them from individuals with symptoms of parkinsonism due to the accumulation of another protein, tau.

15 Mar 2022

Researchers develop a system of synthetic biosensors to assess the response of cancer therapy

Immune checkpoint blockade (ICB) inhibitors have transformed the treatment of cancer and have become the frontline therapy for a broad range of malignancies. It's because they work better than the previous standard of care.

11 Mar 2022

New multi-marker risk algorithm could improve the accuracy of prostate cancer screening

Calculating a person's risk of developing prostate cancer using results from two blood markers would improve the accuracy of screening for the disease, reports a new study led by a UCL researcher.

8 Mar 2022

Melanoma patients do better on immunotherapy than completion lymph node dissection

For years, surgery for patients with stage III melanoma -; melanoma that has spread to the lymph nodes -; involved removing those lymph nodes along with the primary tumor.

4 Mar 2022

Novel approach to generate reliable breast tumor models may pave way for better immunotherapies

The discrepancy between preclinical advances in breast cancer immunotherapy and poor patient outcomes is rooted in the limitations of current breast cancer models. These models often fail to mimic complex interactions between cancer cells and key immune cells present in the tumor microenvironment.

3 Mar 2022

Aggressive brain tumor in children can be identified by analyzing cerebrospinal fluid

It may be possible to identify the presence of an aggressive brain tumor in children by studying their cerebrospinal fluid, according to new research led by Johns Hopkins Kimmel Cancer Center investigators.

2 Mar 2022

Targeting necroptosis using a necroptosis inhibitor lessens myositis-induced muscle weakness

A new study has suggested that treatment to target necroptosis in muscle fibers using a necroptosis inhibitor lessens myositis-induced muscle weakness as well as muscle cell death and inflammation in the muscles. This has been shown to be a promising strategy for treating polymyositis.

2 Mar 2022

Study provides new understanding of the earliest molecular events in Type 1 Diabetes pathogenesis

For the first time, researchers have revealed that during the development of Type 1 Diabetes (T1D), when insulin-producing cells in the pancreas are under attack from T lymphocytes, the cells lining the pancreatic duct reprogram themselves in an attempt to suppress autoimmune T cell responses.

28 Feb 2022

DNA biomarker test helps predict recurrence of HPV-driven oropharyngeal cancer after treatment

A large, multi-institutional study demonstrates that a blood test to detect circulating tumor DNA can accurately predict recurrence of HPV-driven oropharyngeal cancer following treatment.

25 Feb 2022

AI model could be a low-cost, non-invasive option for thyroid cancer screening and staging

A new study finds that an artificial intelligence (AI) model incorporating multiple methods of machine learning accurately detects thyroid cancer and predicts pathological and genomic outcomes through analysis of routine ultrasound images.

24 Feb 2022

Deep-learning based image reconstruction approach may improve detection of breast cancer

Researchers have developed a new image reconstruction approach that could contribute to better breast cancer detection. The deep learning algorithm overcomes a major hurdle in multi-modality imaging by allowing images to be recovered in real time.

24 Feb 2022

‘Injections, injections, injections’: Troubling questions follow closure of sprawling pain clinic chain

On May 13 of last year, the cellphones of thousands of California residents undergoing treatment for chronic pain lit up with a terse text message: "Due to unforeseen circumstances, Lags Medical Centers will be closing effective May 19, 2021."

22 Feb 2022

Scientists use entire human GI tracts to shed light on cellular functions

If you get nervous, you might feel it in your gut. If you eat chili, your gut might revolt, but your friend can eat anything and feel great. You can pop ibuprofen like candy with no ill effects, but your friend's belly might bleed and she might get no pain relief.

21 Feb 2022

Skin cells outside of the hair follicles play large role in the development of a pimple

Acne is among the most common skin diseases in the United States, according to the American Academy of Dermatology Association, affecting up to 50 million Americans each year. It is also among the least studied.

17 Feb 2022

Illumina partners with centers across France to advance a precision medicine approach for patients with late-stage cancer

Joint study will assess clinical value of comprehensive genomic profiling (CGP) on cancer therapy options in patients with advanced disease

From Illumina, Inc. 17 Feb 2022

Human nose organoids provide better understanding of the first steps toward SARS-CoV-2 infection

Preclinical models that recapitulate aspects of human airway disease are essential for the advancement of novel therapeutics and vaccines.

16 Feb 2022