Drug Discovery News and Research

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The drug discovery process begins with recognizing a disease or clinical condition in which there is a lack of adequate medical treatment. Once a potential drug has been identified, pre-clinical research can begin. This process includes several stages; the first of which involves identifying and validating the prospective drug’s target through assay development, high throughput screening, hit identification and finally, lead optimization. Once the pre-clinical process is complete, the newly synthesized drug candidate is selected for future clinical development.

ELRIG UK appoints Nick Clare to board as Vendor Strategy Work Group Lead

The European Laboratory Research & Innovation Group (ELRIG) UK today announced the appointment of Nick Clare to the ELRIG board. He will chair and lead the Vendor Strategy Work Group to help ensure the vendors’ perspectives and interests are represented within the ELRIG board.

From ELRIG (UK) Ltd. 11 May 2023

Leveraging proteomics datasets to discover potential therapeutic targets for cancer patients

A new research perspective was published in Oncotarget's Volume 14 on May 4, 2023, entitled, "Using cancer proteomics data to identify gene candidates for therapeutic targeting."

10 May 2023

Researchers create new "pangenome" that provides better view of human genome

When it was launched in April 2003, the Human Genome Project helped revolutionize biomedical research by providing scientists a reference map that allowed them to analyze DNA sequences for genetic clues to the origins of a host of diseases.

10 May 2023

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

In a University of California, Irvine-led study, researchers have discovered small-molecule drugs with potential clinical utility in the treatment of age-related macular degeneration (AMD), diabetic retinopathy (DR), and retinitis pigmentosa (RP).

9 May 2023

Game-changers reshaping our world: From mRNA vaccines to AI-powered medicine

The paper covers recent breakthroughs in science and technology that can bring immediate and long-term changes to human life while prioritizing sustainability.

8 May 2023

Why the preservation of Australia's biodiversity is essential for human health

Researchers reviewed the significance of preserving Australia's biodiversity for the well-being of human health.

2 May 2023

Paving the Way for New Drugs through Particle Perfection

Do particles hold the power to pave the way for new drugs? In this interview, we speak to Ben Knappett, head of science and applications at Particle Works to find out more!

From Society for Laboratory Automation and Screening (SLAS) 2 May 2023

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

Research discusses recent advances in computer-aided drug discovery, including the use of virtual screening and deep learning methods and their potential to revolutionize the drug discovery process by identifying diverse, potent, and drug-like ligands to protein targets.

28 Apr 2023

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Scripps Research scientists have developed a new strategy for identifying small molecules that can change the function of proteins, offering a promising path for discovering targeted drugs.

27 Apr 2023

Insomnia drug shows potential as an effective treatment for opioid use disorder

The insomnia drug suvorexant (Belsomra) might be an effective treatment for opioid use disorder, according to a preclinical study from Scripps Research.

27 Apr 2023

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

27 Apr 2023

New test reveals FDA-approved antibiotics can effectively treat superbugs

A new test revealed that FDA-approved antibiotics -; available at your neighborhood pharmacy -; can effectively treat superbugs.

27 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

New injectable cell therapy shows promise for treating osteoarthritis

Wake Forest Institute for Regenerative Medicine (WFIRM) scientists have created a promising injectable cell therapy to treat osteoarthritis that both reduces inflammation and also regenerates articular cartilage.

21 Apr 2023

How alcohol intake contributes to increased pain and hypersensitivity

Chronic alcohol consumption may make people more sensitive to pain through two different molecular mechanisms-;one driven by alcohol intake and one by alcohol withdrawal.

21 Apr 2023

Study should spur the development of alternative range of anti-TB inhibitors

Tuberculosis (TB) is one of the deadliest infectious diseases worldwide that is spread in the air like the common cold. TB is caused by the bacterium Mycobacterium tuberculosis (Mtb) and was responsible for approximately 1.6 million deaths in 2021.

20 Apr 2023

Gut bacteria could be responsible for dampening our immune response to COVID-19 vaccine

Gut bacteria that break down a sugar called fucose could be dampening our immune response to the COVID-19 mRNA vaccine, according to a study led by researchers from the Okinawa Institute of Science and Technology.

20 Apr 2023

New biologic inactivates potent opioid and reverses overdose

A new therapeutic designed by Scripps Research chemists can alter the molecular structure of the potent opioid carfentanil, inactivating the opioid and reversing a carfentanil overdose.

18 Apr 2023

AI can identify subtle language and audio changes in patients at early stages of Alzheimer's

New technologies that can capture subtle changes in a patient's voice may help physicians diagnose cognitive impairment and Alzheimer's disease before symptoms begin to show, according to a UT Southwestern Medical Center researcher who led a study published in the Alzheimer's Association publication Diagnosis, Assessment & Disease Monitoring.

12 Apr 2023

Researchers construct super-sized nanocage for delivering larger drug cargoes

Think about how frustrating it is to try to fit a gift into a box that is too small. Sometimes you just need a bigger box.

6 Apr 2023

Drug Discovery News and Research

Further Reading

ELRIG UK appoints Nick Clare to board as Vendor Strategy Work Group Lead

Leveraging proteomics datasets to discover potential therapeutic targets for cancer patients

Researchers create new "pangenome" that provides better view of human genome

New small-molecule drugs show potential clinical utility in treating world’s leading causes of blindness

Game-changers reshaping our world: From mRNA vaccines to AI-powered medicine

Why the preservation of Australia's biodiversity is essential for human health

Paving the Way for New Drugs through Particle Perfection

Revolutionizing drug discovery: Giga-scale screening unleashes power of AI and virtual libraries

New strategy for identifying small molecules offers a promising path for discovering targeted drugs

Insomnia drug shows potential as an effective treatment for opioid use disorder

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

New test reveals FDA-approved antibiotics can effectively treat superbugs

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

New injectable cell therapy shows promise for treating osteoarthritis

How alcohol intake contributes to increased pain and hypersensitivity

Study should spur the development of alternative range of anti-TB inhibitors

Gut bacteria could be responsible for dampening our immune response to COVID-19 vaccine

New biologic inactivates potent opioid and reverses overdose

AI can identify subtle language and audio changes in patients at early stages of Alzheimer's

Researchers construct super-sized nanocage for delivering larger drug cargoes

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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