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New system measures strength of communication between muscle cells and motor neurons

In an effort to identify the underlying causes of neurological disorders that impair motor functions such as walking and breathing, UCLA researchers have developed a novel system to measure the communication between stem cell-derived motor neurons and muscle cells in a Petri dish.

5 May 2012

Researchers identify new mechanism that causes choroidal neovascularization

Sloppy shipping of a donated human retina to an Indiana University researcher studying a leading cause of vision loss has inadvertently helped uncover a previously undetected mechanism causing the disease. The discovery has led researchers to urge review of how millions of dollars are spent investigating the cause of a type of age-related macular degeneration called choroidal neovascularization.

5 May 2012

PDE4 enzyme regulates division of tumour cells and blood vessel growth in cancer tissue

Lung cancer is the leading cause of cancer death throughout the world. Standard treatment methods do not usually result in long-term recovery. In addition to the proliferation of the tumour cells, the growth of blood vessels controls tumors development. The blood vessel growth is controlled by several signalling molecules. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim and Justus Liebig University Giessen have discovered a molecule that plays a key role in this process. They succeeded in reducing tumour growth in their experiments by blocking the phosphodiesterase PDE4.

5 May 2012

Inland Empire Stem Cell Consortium to enhance collaboration among three universities

Stem cell research laboratories at the University of California, Riverside, Loma Linda University and the California State University at San Bernardino have formed the "Inland Empire Stem Cell Consortium" to enhance collaboration among the three universities and bring focus to stem cell work being done in inland Southern California.

5 May 2012

Research identifies molecular trigger of fibroid uterine tumors

Fibroid uterine tumors affect an estimated 15 million women in the United States, causing irregular bleeding, anemia, pain and infertility. Despite the high prevalence of the tumors, which occur in 60 percent of women by age 45, the molecular cause has been unknown.

5 May 2012

Andrew Technologies launches HydraSolve Lipoplasty System at ASAPS meeting

Andrew Technologies, LLC launched the HydraSolve Lipoplasty System today at the American Society of Aesthetic Plastic Surgery (ASAPS) in Vancouver, BC.

5 May 2012

Awake mental replay essential for making informed choices

Awake mental replay of past experiences is essential for making informed choices, suggests a study in rats. Without it, the animals- memory-based decision-making faltered, say scientists funded by the National Institutes of Health. The researchers blocked learning from, and acting on, past experience by selectively suppressing replay - encoded as split-second bursts of neuronal activity in the memory hubs of rats performing a maze task.

4 May 2012

New light on many biological differences between individual breast cancers

New findings presented at Europe's leading breast cancer translational research conference this year shed new light on the many biological differences between individual breast cancers.

4 May 2012

Potential breast cancer patients for new immune-targeting therapies

Breast cancer patients whose tumors express high levels of genes related to immune response are more likely to have their tumor completely eradicated by pre-operative chemotherapy compared to patients with low expression of these genes, Belgian researchers report at the 4th IMPAKT Breast Cancer Conference in Brussels, Belgium.

4 May 2012

New analysis may help identify breast cancer patients who will benefit from immune suppressant

A new analysis may help doctors identify breast cancer patients who will benefit from treatment with the immune suppressant drug everolimus, say French researchers at the 4th IMPAKT Breast Cancer Conference in Brussels, Belgium.

4 May 2012

An Achilles heel within cells that bacteria exploit to cause infection

Scientists have discovered an Achilles heel within our cells that bacteria are able to exploit to cause and spread infection.

4 May 2012

Researchers identify new functions of cohesin SA1 that are relevant for cancer and CdLS

Cohesin is a ring-shaped protein complex involved in the spatial organization of the genome and in mitotic chromosome structure. Vertebrate somatic cells have two versions of cohesin that contain either SA1 or SA2, but their functional specificity has been largely ignored. Researchers of the Spanish National Cancer Research Centre (CNIO) under the direction of Ana Losada have identified new functions of cohesin SA1 that are relevant for two human diseases, cancer and Cornelia de Lange Syndrome.

4 May 2012

Imaging surveillance an acceptable alternative to surgical excision in patients with benign papilloma

Imaging surveillance is an acceptable alternative to surgical excision in patients with benign papilloma, diagnosed at breast core biopsy without cell abnormalities, a new study shows.

4 May 2012

U of A engineers develop wireless health-monitoring system

An interdisciplinary team of engineers at the University of Arkansas has developed a wireless health-monitoring system that gathers critical patient information, regardless of the patient's location, and communicates that information in real time to a physician, hospital or the patient herself.

4 May 2012

TGen to lead multidisciplinary search for new drugs that could help treat GBM

The Translational Genomics Research Institute (TGen) will lead a multidisciplinary search for new drugs that could help treat the most common and lethal form of brain cancer.

4 May 2012

Alnylam first quarter revenues decrease to $20.6 million

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, today reported its consolidated financial results for the first quarter 2012, and company highlights.

4 May 2012

Researchers investigate hydrogels' potential in drug delivery

The flexible properties of hydrogels - highly absorbent, gelatinous polymers that shrink and expand depending on environmental conditions such as humidity, pH and temperature - have made them ideal for applications from contact lenses to baby diapers and adhesives.

4 May 2012

Study: Breast cancer in young women is enriched with aggressive basal-like tumors

Breast cancer in young women is a biologically unique disease that requires customized management strategies, researchers report at the 4th IMPAKT Breast Cancer Conference, in Brussels, Belgium.

4 May 2012

New genetic pathway influences spread of cancer cells

In a new study from Lawson Health Research Institute, Dr. Joseph Torchia has identified a new genetic pathway influencing the spread of cancer cells. The discovery of this mechanism could lead to new avenues for treatment.

4 May 2012

UCLA creates crowd-sourced online gaming system to detect malaria

Online crowd-sourcing - in which a task is presented to the public, who respond, for free, with various solutions and suggestions - has been used to evaluate potential consumer products, develop software algorithms and solve vexing research-and-development challenges. But diagnosing infectious diseases?

4 May 2012