Cell Death News and Research

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Human embryonic stem cell lines accumulate changes in their genetic material over time

The findings do not limit the utility of the cells for some types of research or for some future clinical applications, the researchers say, but draw attention to the need to closely monitor stem cell lines for genetic changes and to study how these alterations affect the cells' behavior.

6 Sep 2005

Human embryonic stem cell lines accumulate changes in their genetic material over time

5 Sep 2005

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

A study published by The Burnham Institute in the September edition of Molecular Cell reports that a cell-cycle checkpoint protein, known to be activated by an important class of anticancer drugs, may play crucial roles in both the hampering of therapeutic actions and aiding cancer cells to "recover" and start dividing again after treatment with these drugs.

5 Sep 2005

Macrophages kill bacteria - but not always

Macrophages are effective weapons used by our immune system to absorb and digest pathogenic intruders. Some bacteria, however, can subvert this defence mechanism and even multiply within the macrophages.

1 Sep 2005

Another use for Botox - enlarged prostate

Botox, appears to alter specific cellular processes that contribute to prostate enlargement according to new study results presented by researchers from the University of Pittsburgh and Chang Gung Memorial Hospital in Taiwan at the International Continence Society annual meeting in Montreal.

31 Aug 2005

Virginia Tech engineer investigates enzyme link to Huntington's, Parkinson's, and Alzheimer diseases

Several neurologically based afflictions, such as Huntington's, Parkinson's, and Alzheimer diseases, have been correlated to a higher than normal presence of a specific type of enzymes, called transglutaminases (TGase) in the human body.

30 Aug 2005

Discovery of multiple isoforms of the p53 tumor suppressor protein

25 years after the initial discovery of p53, Dr. David Lane and colleagues at the University of Dundee have discovered multiple isoforms of the p53 tumor suppressor protein.

29 Aug 2005

New vaccine protects more effectively against tuberculosis

Max Planck researchers have uncovered the mechanism by which the new genetically engineered tuberculosis vaccine functions.

28 Aug 2005

Immunity - another important function of the mitochondria

Researchers have discovered a surprise lurking inside mitochondria, the power plants that are present in every cell. It turns out that these powerhouses also contain a protein that triggers the immune system to attack viral invaders.

28 Aug 2005

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

A protein previously thought to merely hinder the activity of a key cellular protein linked to cancer cell death, now appears to mimic the cellular signaling of that protein; potentially leading to the development of lymphoma.

22 Aug 2005

Malfunctioning bone marrow cells cause neuropathy in many people with diabetes

Malfunctioning bone marrow cells that produce insulin appear to cause a dangerous nerve condition called neuropathy that disables many people with diabetes, said a research team led by Baylor College of Medicine (BCM) in Houston.

22 Aug 2005

Discovery of signaling component that influences spread of breast cancer cells

Researchers at the Virginia Commonwealth University Massey Cancer Center have found a new signaling component that influences movement of human breast cancer cells toward epidermal growth factor.

22 Aug 2005

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Johns Hopkins Kimmel Cancer Center scientists have found that interferon, used for 30 years to treat blood cancers, multiple sclerosis and hepatitis, selectively kills colon cancer cells when combined with another standard chemotherapy agent.

16 Aug 2005

Developmental culling and cancer

A new study reveals that a diverse group of apparently unrelated genes that are associated with pheochromocytoma intersect at a common pathway that drives the necessary culling of cells.

16 Aug 2005

BioLife Solutions granted U.S. patent covering new method of preserving cells, tissues or organs

BioLife Solutions announced today that it was granted a U.S. patent that covers the methods and compositions for the preservation of cells, tissues or organs in the vitreous state.

15 Aug 2005

Experimental therapy could offer new way to treat spine damage

An experimental therapy that combines stem cells and gene therapy to repair spinal cord injuries in rats may lead to a new way to treat the same injury in humans.

15 Aug 2005

Protein that protects the body from tissue damage also increases the risk of tumors

You win some, you lose some. A protein that protects the body from tissue damage also increases the risk of tumors, according to a study conducted at Washington University School of Medicine in St. Louis. Moderate reduction of the protein level protects against tumor formation but increases susceptibility to tissue injury.

11 Aug 2005

Cell Death News and Research

Human embryonic stem cell lines accumulate changes in their genetic material over time

Human embryonic stem cell lines accumulate changes in their genetic material over time

New findings suggest balancing Chk1 activity will produce less toxic cancer drugs

Macrophages kill bacteria - but not always

Another use for Botox - enlarged prostate

Virginia Tech engineer investigates enzyme link to Huntington's, Parkinson's, and Alzheimer diseases

Discovery of multiple isoforms of the p53 tumor suppressor protein

New vaccine protects more effectively against tuberculosis

Immunity - another important function of the mitochondria

Protein thought to promote lymphoma by merely preventing cancer cells from dying appears to actively promote cancer cell growth

Malfunctioning bone marrow cells cause neuropathy in many people with diabetes

Discovery of signaling component that influences spread of breast cancer cells

Interferon selectively kills colon cancer cells when combined with irinotecan chemotherapy agent

Developmental culling and cancer

BioLife Solutions granted U.S. patent covering new method of preserving cells, tissues or organs

Experimental therapy could offer new way to treat spine damage

Protein that protects the body from tissue damage also increases the risk of tumors

Defect in the gene that makes YAP might contribute to cancer

Pig brain cell transplant looks hopeful for treating Huntington's disease

Strawberries most effective at inducing cancer cell death

eBook: A Researcher's Guide to Cell Death Mechanisms eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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