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Catenane magic: Boosting protein stability and resilience with interlocking rings

This study is led by Prof. Wen-Bin Zhang (College of Chemistry and Molecular Engineering, Peking University & Beijing Academy of Artificial Intelligence) and Dr. Jing Fang (College of Chemistry and Molecular Engineering, Peking University).

29 Dec 2023

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

A new study shows thousands more patients diagnosed with colorectal and endometrial cancers could benefit from immunotherapy than are currently offered it.

29 Dec 2023

Brain injury markers found in the blood months after COVID-19 infection

A new study published today (22 December 2023) in Nature Communications details that markers of brain injury are present in the blood many months after COVID-19 infection, despite inflammation blood tests being normal.

22 Dec 2023

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Researchers have identified a previously unrecognized class of antibodies-;immune system proteins that protect against disease-;that appear capable of neutralizing multiple forms of flu virus.

21 Dec 2023

Shedding new light on the hidden organization of the cytoplasm

Back in 2018, the lab of Christine Mayr, MD, PhD, at Memorial Sloan Kettering Cancer Center (MSK) introduced the world to a key cellular component that had been hiding in plain sight.

21 Dec 2023

UVA Alzheimer's study pinpoints how tau protein damages brain cells

University of Virginia Alzheimer's researchers have discovered how harmful tau proteins damage the essential operating instructions for our brain cells, a finding which could lead to new treatments.

20 Dec 2023

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Amidst a backdrop of industry-wide hurdles like inflation, talent scarcities, and stringent regulatory landscapes, Nona Biosciences is showing great promise as an emerging global leader in biotechnology.

From Nona BioSciences 19 Dec 2023

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

Researchers investigated the anticancer effects of drugs targeting human tumor-associated macrophages (TAMs) in vivo. In humanized murine models, they tested the effectiveness of an antibody to human signal regulatory protein alpha (SIRPα) for cancer immunotherapy.

19 Dec 2023

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

B cell deficiency is a common condition that can result either from immunosuppressant drugs used to treat autoimmune disease or certain cancers -; such as rituximab (RTX) -; or from natural immune deficiency.

18 Dec 2023

Maternal microbiome's pivotal role in shaping fetal and neonatal immune systems during pregnancy

Review in Nature Reviews Gastroenterology and Hepatology explores how the maternal microbiome during pregnancy influences the immune systems of the mother, fetus, and neonate, highlighting its impact on long-term health outcomes and the development of pregnancy complications.

18 Dec 2023

Two proteins in the blood could predict dengue severity

Scientists and clinicians at Nanyang Technological University, Singapore (NTU Singapore) and the National Centre for Infectious Diseases (NCID) have identified two compounds - sST2 and suPAR - in the blood of dengue patients that could determine if a patient is at risk of severe dengue in the early phases of the disease.

18 Dec 2023

Deep learning designs high-affinity protein binders for bioactive helical peptides

A new study Dec. 18 in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring.

18 Dec 2023

New discovery could expand the possibilities for medical use of Botox

PSI researchers have discovered a surprising trick that could expand the possibilities for medical use of botulinun toxin A1, better known under the name Botox, as an active agent.

18 Dec 2023

Experts from leading institutions launch Pandemic Research Alliance for collaborative virus defense

World-renowned professors from six leading institutions in four countries launched the Pandemic Research Alliance (PRA) today (4 December) to drive concerted research into respiratory viruses from animals to humans, improved surveillance, and new solutions to better manage the next pandemic.

17 Dec 2023

UVA biomedical engineer unveils hidden immune symphony during pregnancy

Sepideh Dolatshahi, an assistant professor of biomedical engineering at the University of Virginia, is spearheading an exploration of systems immunology in its crucial development phase -; during pregnancy.

15 Dec 2023

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Study introduces a novel dry powder aerosol COVID-19 vaccine, showing its effectiveness in inducing strong immune responses and offering protection against various SARS-CoV-2 strains, including Omicron.

15 Dec 2023

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

Study evaluates the single-dose intranasal spray vaccine dNS1-RBD, finding it effective against symptomatic COVID-19, particularly in reducing severe symptoms and respiratory issues.

15 Dec 2023

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies.

14 Dec 2023

Advancements in food allergy research promise improved diagnosis and treatment options

A review in the Journal of Allergy and Clinical Immunology discusses the global trends in food allergy prevalence, with stabilization in developed regions and an increase in developing countries, alongside advancements in understanding the mechanisms, diagnosis, and treatment of food allergies.

13 Dec 2023

Smaller mpox vaccine doses and intradermal delivery elicit detectable immune response, study shows

Delivering the two-dose mpox vaccine, called JYNNEOS, in smaller than the usual FDA-approved doses, and by injection between layers of the skin rather than by the standard route under the skin, produced a detectable immune response, a new study shows.

13 Dec 2023

Antibodies News and Research

Catenane magic: Boosting protein stability and resilience with interlocking rings

New study expands immunotherapy eligibility for colorectal and endometrial cancer patients

Brain injury markers found in the blood months after COVID-19 infection

Previously unrecognized class of antibodies can broadly neutralize multiple virus strains

Shedding new light on the hidden organization of the cytoplasm

UVA Alzheimer's study pinpoints how tau protein damages brain cells

Bridging ideas to IND: Nona Biosciences' year of impact in biotechnology

Mice with humanized immune systems test new cancer therapeutic approach that blindfolds immune cells to the body’s self-recognition system

T-cells step up to offer protection against COVID-19 in B-cell deficient patients

Maternal microbiome's pivotal role in shaping fetal and neonatal immune systems during pregnancy

Two proteins in the blood could predict dengue severity

Deep learning designs high-affinity protein binders for bioactive helical peptides

New discovery could expand the possibilities for medical use of Botox

Experts from leading institutions launch Pandemic Research Alliance for collaborative virus defense

UVA biomedical engineer unveils hidden immune symphony during pregnancy

New dry powder aerosol COVID-19 vaccine shows promise against multiple virus strains

Intranasal COVID-19 vaccine shows promise in reducing severe symptoms

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Advancements in food allergy research promise improved diagnosis and treatment options

Smaller mpox vaccine doses and intradermal delivery elicit detectable immune response, study shows

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