Lungs News and Research

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Novel method uses lasers to carve paths inside biocompatible gels

Future medicine is bound to include extensive tissue-engineering technologies such as organs-on-chips and organoids - miniature organs grown from stem cells. But all this is predicated on a simple yet challenging task: controlling cellular behavior in three dimensions.

23 Jun 2016

Scientists streamline total synthesis of uncialamycin drug

A team led by Rice University scientists has improved the production of a potent anti-tumor antibiotic known as uncialamycin.

23 Jun 2016

Adherence to cancer prevention guidelines on diet and physical activity may reduce disease incidence

"Behaviors such as poor diet choices, physical inactivity, excess alcohol consumption and unhealthy body weight could account for more than 20 percent of cancer cases, and could, therefore, be prevented with lifestyle modifications," Kohler said, adding that when tobacco exposure is considered, these modifiable issues are believed to be factors in two-thirds of U.S. cancer deaths.

23 Jun 2016

Novel combination therapy slows cancer growth in patients with advanced solid tumors

A phase 1 clinical trial testing a novel combination therapy developed by scientists at VCU Massey Cancer Center slowed the growth of cancer in the majority of trial participants, which were patients with advanced solid tumors.

22 Jun 2016

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Few threats to public health are as perilous as cigarette smoking, with more than 435,000 Americans dying each year of tobacco-related pulmonary illnesses such as chronic obstructive pulmonary disease (COPD).

22 Jun 2016

Unseen health risks of aortic stenosis: an interview with Dr Shelley Rahman Haley

Aortic stenosis means narrowing of the aortic valve, which is the out flow valve from the left ventricle, the pumping chamber of the heart. This is the valve which opens to allow blood to flood out of the heart and all-round the body.

22 Jun 2016

Researchers seek to develop novel antibody to treat glioblastoma

Scientists of Helmholtz Zentrum München and the Munich University Hospital are developing a novel antibody to treat brain tumors.

22 Jun 2016

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

Researchers from the University of Chicago have shown that microbiota—the bacteria, viruses and other microbes living on the skin and in the digestive system—play an important role in the body's ability to accept transplanted skin and other organs.

22 Jun 2016

E-cigarette use modifies gene expression important for upper airway immune defense

When we smoke cigarettes, dozens of genes important for immune defense are altered in the epithelial cells that line the respiratory tract. Several of these changes likely increase the risk of bacterial infections, viruses, and inflammation.

21 Jun 2016

New blood test could help predict severity of pulmonary arterial hypertension

Johns Hopkins Medicine researchers report that rising blood levels of a protein called hematoma derived growth factor (HDGF) are linked to the increasing severity of pulmonary arterial hypertension, a form of damaging high blood pressure in the lungs.

20 Jun 2016

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Measuring antibody levels in the blood could be used to detect a person's heart attack risk after researchers, part-funded by the British Heart Foundation, discovered that higher levels of these antibodies are linked to a lower heart attack risk.

20 Jun 2016

Researchers seek to develop inexpensive electronic nose for breath analysis

Researchers at the Texas Analog Center of Excellence (TxACE) at UT Dallas are working to develop an affordable electronic nose that can be used in breath analysis for a wide range of health diagnosis.

17 Jun 2016

Legions of immune cells play complex role to destroy Legionella bacteria

Immunologists and microbiologists from the University of Melbourne's Bio21 Molecular Science and Biotechnology Institute and the Peter Doherty Institute for Infection and Immunity - a joint venture between the University of Melbourne and Royal Melbourne Hospital - have led a study that defined a new cell type responsible for turning the attack back on the bacteria.

17 Jun 2016

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Researchers at Johns Hopkins report that a type of lab-grown human nerve cells can partner with heart muscle cells to stimulate contractions.

17 Jun 2016

Elevated levels of CXCL10 protein could help diagnose cGvHD in blood, bone marrow transplant patients

A new study published today in the journal Blood has identified a protein that could diagnose chronic graft-versus-host disease (cGvHD), a serious, long-term complication that affects some patients after a blood and bone marrow transplant.

17 Jun 2016

RVFV uses cancer pathway to hijack host cell and cause infection

Viruses can't live without us -- literally. As obligate parasites, viruses need a host cell to survive and grow. Scientists are exploiting this characteristic by developing therapeutics that close off pathways necessary for viral infection, essentially stopping pathogens in their tracks.

17 Jun 2016

Women working long hours may be working themselves sick

Research published this week shows that women working long hours for many years are at increased risk of developing life-threatening illnesses. Diabetes, cancer, heart trouble and arthritis were three times more common among women who worked an average of 60 hours or more per week for 30 years compared with women working fewer hours.

17 Jun 2016

Lungs News and Research

Novel method uses lasers to carve paths inside biocompatible gels

Scientists streamline total synthesis of uncialamycin drug

Adherence to cancer prevention guidelines on diet and physical activity may reduce disease incidence

Novel combination therapy slows cancer growth in patients with advanced solid tumors

Researchers reveal novel mechanism of smoke induced collapse of protein homeostasis in COPD

Unseen health risks of aortic stenosis: an interview with Dr Shelley Rahman Haley

Researchers seek to develop novel antibody to treat glioblastoma

Composition of microbiota plays significant role in body's ability to accept transplanted tissue

E-cigarette use modifies gene expression important for upper airway immune defense

New blood test could help predict severity of pulmonary arterial hypertension

People with higher levels of IgG/IgM antibodies less likely to have heart attack

Researchers seek to develop inexpensive electronic nose for breath analysis

Legions of immune cells play complex role to destroy Legionella bacteria

Cells grown from pluripotent stem cells can pair with heart muscle cells to stimulate contractions

Elevated levels of CXCL10 protein could help diagnose cGvHD in blood, bone marrow transplant patients

RVFV uses cancer pathway to hijack host cell and cause infection

Women working long hours may be working themselves sick

New device may enable painless, effective diagnosis of Helicobacter in exhaled air

Multi-purpose handheld ultrasound scanner images entire torso and heart

Long work hours may triple risk of life-threatening illnesses in women

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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