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Air pollution becomes leading risk factor for stroke worldwide

Air pollution – including environmental and household air pollution - has emerged as a leading risk factor for stroke worldwide, associated with about a third of the global burden of stroke in 2013, according to a new study published in The Lancet Neurology journal.

13 Jun 2016

Rehabilitation programmes can help reverse frailty in older COPD patients

One in four patients with COPD referred for exercise rehabilitation are frail, but nevertheless can respond favourably to rehabilitation and their frailty can be reversed, finds a new study led by King's College London and Royal Brompton & Harefield NHS Foundation Trust.

13 Jun 2016

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

As the promise of using regenerative stem cell therapies draws closer, a consortium of biomedical scientists reports about 30 percent of induced pluripotent stem cells they analyzed from 10 research institutions were genetically unstable and not safe for clinical use.

10 Jun 2016

New RNA aptamer can prevent pathogenic protein misfolding

Several diseases occur when mutations cause misfolding of proteins. These include "serpinopathies" which is a group of rare heritable diseases. They are caused by mutations of so-called "serpin" inhibitors of proteolytic enzymes involved in blood coagulation, tissue remodeling, and other important physiological functions.

10 Jun 2016

New PsA-comorbidity index may help identify patients at risk of hospitalisation and premature death

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that a newly developed method of evaluating the impact of different comorbidities in patients with Psoriatic Arthritis (PsA) can be used to prospectively identify those PsA patients at greater risk of hospitalisation and premature death.

10 Jun 2016

Air pollution exposure may have direct role in triggering lupus among children and adolescents

The results of a study presented today at the European League Against Rheumatism Annual Congress show for the first time that an individual's exposure to air pollution may have a direct role in triggering disease activity as well as airway inflammation in children and adolescents with Systemic Lupus Erythematosus (SLE).

10 Jun 2016

Pre-procedure medication regimen could lower incidence of hospital readmission in lung caner patients

Researchers at the University of Cincinnati College of Medicine have found that putting liver cancer patients on a medication regimen prior to undergoing a certain treatment could lead to shorter hospital stays and less chance for readmission due to complications.

10 Jun 2016

Surgery improves survival in late-stage NSCLC patients

Patients with late-stage, non-small cell lung cancer (NSCLC) who have surgery have better survival rates than those who don't, but fewer of these patients are undergoing surgery, UC Davis researchers have found.

9 Jun 2016

Simple breath test shows promise in identifying lung cancer recurrence after surgery

A single breath may be all it takes to identify the return of lung cancer after surgery, according to a study posted online today by The Annals of Thoracic Surgery.

9 Jun 2016

PD surgery improves quality of life in patients with malignant pleural mesothelioma

Although surgery can prolong the lives of patients with an aggressive type of cancer called malignant pleural mesothelioma, many patients avoid the operation for fear it will degrade their quality of life.

9 Jun 2016

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

People with cancer are often told by their doctors approximately how long they have to live, and how well they will respond to treatments, but what if there were a way to improve the accuracy of doctors' predictions?

9 Jun 2016

New effort in biomedical engineering may improve heart repair

Jianyi "Jay" Zhang, M.D., Ph.D., brought his biomedical engineering expertise to the University of Alabama at Birmingham to fix hearts.

9 Jun 2016

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

In a pair of firsts, researchers at Case Western Reserve University and Massachusetts Institute of Technology have shown that the drug candidate phenanthriplatin can be more effective than an approved drug in vivo, and that a plant-virus-based carrier successfully delivers a drug in vivo.

9 Jun 2016

New paediatric exoskeleton aims to support children with spinal muscular atrophy

Furthermore, it will also be used in physiotherapy in hospitals to prevent the secondary effects associated with the loss of mobility in this illness. The technology, which has been patented and licensed jointly by CSIC and its technology-based business unit, Marsi Bionics, is currently in the preclinical phase.

9 Jun 2016

Mathematical approach can help achieve optimal dosing for various drugs

In treating diseases with drugs, dosing is critical; too little is ineffective, while too much can be lethal. Colorado State University's Brad Reisfeld takes a mathematical approach to achieving optimal dosing for various drugs.

9 Jun 2016

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

A new technology suitable for practical clinical testing can detect KRAS gene mutations in lung and colorectal cancers and could thereby facilitate targeted therapies, according to a new report in The Journal of Molecular Diagnostics.

8 Jun 2016

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

Identifying the cell of origin is crucial to understanding how a tumor develops and metastasizes and for developing targeted therapies.

8 Jun 2016

LA-NSCLC patients treated at high-volume centers survive longer

Lung cancer is the leading cause of cancer-related death in the United States and is estimated to have contributed to 221,200 new cases and 158,040 deaths in 2015 alone. A secondary analysis of NRG Oncology's clinical trial RTOG 0617, published in the Journal of the National Cancer Institute, was initiated in an effort to evaluate the effect of institution accrual volume on clinical outcomes among patients receiving chemoradiation for locally advanced non-small cell lung cancer (LA-NSCLC).

8 Jun 2016

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

When it comes to cystic fibrosis (CF), more than 2,000 different genetic mutations have been reported. However, only 200 of them have been categorized - leaving a genetic soup of 1,800 others for scientists and genetic counselors to figure out.

8 Jun 2016

Coagadex now available for rare bleeding disorder patients in the UK

Bio Products Laboratory, Limited (BPL) today announced that Coagadex is now available for patients in the UK.

7 Jun 2016

Lungs News and Research

Air pollution becomes leading risk factor for stroke worldwide

Rehabilitation programmes can help reverse frailty in older COPD patients

About 30% of iPSCs not safe for clinical use, report multi-institutional researchers

New RNA aptamer can prevent pathogenic protein misfolding

New PsA-comorbidity index may help identify patients at risk of hospitalisation and premature death

Air pollution exposure may have direct role in triggering lupus among children and adolescents

Pre-procedure medication regimen could lower incidence of hospital readmission in lung caner patients

Surgery improves survival in late-stage NSCLC patients

Simple breath test shows promise in identifying lung cancer recurrence after surgery

PD surgery improves quality of life in patients with malignant pleural mesothelioma

UCLA scientists develop statistical method for conducting survival analysis of cancer patients

New effort in biomedical engineering may improve heart repair

Drug candidate delivered by plant-virus-based carrier shows promise for triple-negative breast cancer

New paediatric exoskeleton aims to support children with spinal muscular atrophy

Mathematical approach can help achieve optimal dosing for various drugs

New technology can detect KRAS gene mutations, facilitate targeted therapies for lung and colorectal cancers

Researchers identify lymphatic endothelial lineage that shows potential for new anti-cancer treatment

LA-NSCLC patients treated at high-volume centers survive longer

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

Coagadex now available for rare bleeding disorder patients in the UK

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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