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Surviving without glucose: uridine-derived ribose as an alternative energy source

Researchers attempted to identify new genes and molecular pathways that might supply energy when the availability of glucose or other nutrients is limited.

22 May 2023

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Rheumatoid arthritis (RA) is an autoimmune disease characterized by joint deterioration. The clinical outcomes of patients with active RA can be improved using anti-rheumatic medications, such as methotrexate (MTX).

22 May 2023

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

Excess sugar hampers cells that renew the colon's lining in a mouse model of inflammatory bowel disease (IBD), according to a new study by University of Pittsburgh scientists.

22 May 2023

$OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women$

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

The commonly used Fracture Risk Assessment Tool (FRAX), which includes self-identified race and ethnicity information, and the Osteoporosis Self-Assessment Tool (OST), which does not, had suboptimal performance in determining major osteoporotic fracture risk across racial/ethnic categories in younger postmenopausal women.

22 May 2023

Regular exercise may reduce bleeding in individuals with intracerebral hemorrhage

Regular physical activity and exercise may reduce bleeding in individuals with intracerebral hemorrhage, a University of Gothenburg study shows.

22 May 2023

Women who experience adverse pregnancy outcomes have higher stroke risk

Investigators from the Smidt Heart Institute at Cedars-Sinai found that women who experience an adverse pregnancy outcome-; such as gestational hypertension, preeclampsia or preterm birth-; have a higher risk of developing stroke in their lifetime, and at a younger age.

22 May 2023

Study finds higher risk of mortality among women than men after heart attack

Women are more than twice as likely to die after a heart attack than men, according to research presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology.

22 May 2023

Cancer researchers join together to fight lethal childhood brain cancer

Virginia Tech researchers with the Fralin Biomedical Research Institute at VTC have joined a Children's National Hospital effort to treat deadly brain tumors with ultrahigh frequency sound waves.

22 May 2023

Targeting mucus plugs could help prevent deaths from COPD, study suggests

A retrospective analysis of patient data from the COPDGene study suggests that targeting mucus plugs could help prevent deaths from chronic obstructive pulmonary disease-;the fourth leading cause of death in the United States.

22 May 2023

Blood vessel abnormalities in the eye could drive Alzheimer's disease

Blood vessel abnormalities in the eye are a major factor in the progression of Alzheimer's disease, according to research from Cedars-Sinai investigators published in the peer-reviewed journal Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

22 May 2023

Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40%

Sacubitril/valsartan leads to greater reduction in plasma NT-proBNP levels compared to valsartan alone after stabilization for worsening heart failure in patients with an ejection fraction (EF) above 40%, according to late breaking science presented today at Heart Failure 2023, a scientific congress of the European Society of Cardiology (ESC), and published in the Journal of the American College of Cardiology.

22 May 2023

Cardiovascular risk score decreases after one year of semaglutide use in obese patients, study shows

New research presented at this year's European Congress on Obesity in Dublin, Ireland shows that patients treated with the obesity drug semaglutide have a decreased cardiovascular risk score after one year of use.

22 May 2023

People with higher long-term hair glucocorticoid levels more likely to develop heart, circulatory diseases

New research being presented at this year's European Congress on Obesity (ECO) in Dublin, Ireland (17-20 May) suggests that glucocorticoid levels (a class of steroid hormones secreted as a response to stress) present in the hair of individuals may indicate which of them are more likely to suffer from cardiovascular diseases (CVD) in the future.

22 May 2023

Multicenter, 1-year-long real-world study shows effectiveness of semaglutide for weight loss

New research presented at this year's European Congress on Obesity (ECO2023, Dublin, 17-20 May) shows that the obesity drug semaglutide is effective for weight loss in a multicentre, 1-year-long real-world study.

22 May 2023

University Hospitals Birmingham partners with Qureight for lung disease research

University Hospitals Birmingham (UHB) has partnered with medical technology company, Qureight, to build more diverse artificial intelligence (AI) models that accurately reflect communities; a world-first lung disease research partnership.

22 May 2023

Study helps clarify the underlying cause of chest symptoms in angina

An intensive study into the treatment of angina has found that the use of tests for small blood vessel function in the heart clarify the underlying cause of the condition.

22 May 2023

Genetic insights unveil promising therapeutic targets for critical COVID-19

Critical COVID-19 illness reveals genetic associations with immunomodulatory therapies, as identified in a comprehensive analysis of 24,202 cases. This study uncovers novel genome-wide significant associations, highlighting potential druggable targets for inflammatory signaling, immunometabolism, and viral replication, offering insights into therapeutic implications.

21 May 2023

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Research uncovers the association between multiple sclerosis (MS) and antibody reactivity to specific amino acids in CRYAB, along with the increased risk when combined with high EBNA1 responses. The study provides evidence of antibody and T cell cross-reactivity between EBNA1 and CRYAB, highlighting the role of EBV adaptive immune responses in MS development.

21 May 2023

Study finds significant amount of clotting in the arteries of patients with STEMI and COVID-19

The latest analysis from The North American COVID-19 STEMI (NACMI) was presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions.

19 May 2023

Study reports improved deliverability, tracking, and deployment of next-generation Evolut FX TAVR system

Results from the Evolut FX TAVR (Transcatheter Aortic Valve Replacement) Clinical Survey were presented today as late-breaking clinical research at the Society for Cardiovascular Angiography & Interventions (SCAI) 2023 Scientific Sessions.

19 May 2023

Blood News and Research

Surviving without glucose: uridine-derived ribose as an alternative energy source

Study shows the potential of TAp63 as a new therapeutic target for rheumatoid arthritis

Study could help understand why limiting sugary foods can ease symptoms for IBD patients

OST performs better than FRAX in determining osteoporotic fracture risk in younger postmenopausal women

Regular exercise may reduce bleeding in individuals with intracerebral hemorrhage

Women who experience adverse pregnancy outcomes have higher stroke risk

Study finds higher risk of mortality among women than men after heart attack

Cancer researchers join together to fight lethal childhood brain cancer

Targeting mucus plugs could help prevent deaths from COPD, study suggests

Blood vessel abnormalities in the eye could drive Alzheimer's disease

Study shows potential benefit of sacubitril/valsartan in heart failure patients with EF over 40%

Cardiovascular risk score decreases after one year of semaglutide use in obese patients, study shows

People with higher long-term hair glucocorticoid levels more likely to develop heart, circulatory diseases

Multicenter, 1-year-long real-world study shows effectiveness of semaglutide for weight loss

University Hospitals Birmingham partners with Qureight for lung disease research

Study helps clarify the underlying cause of chest symptoms in angina

Genetic insights unveil promising therapeutic targets for critical COVID-19

Cross-reactivity between Epstein-Barr virus and protein in multiple sclerosis sheds light on disease development

Study finds significant amount of clotting in the arteries of patients with STEMI and COVID-19

Study reports improved deliverability, tracking, and deployment of next-generation Evolut FX TAVR system

Decoding Cannabis: Differentiating Hemp and Marijuana

Deciphering the Microbiome with The Microsetta Initiative

Leveraging the power of automation to boost research

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