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Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

The gene ECHS1 encodes for enoyl-CoA hydratase short-chain 1, a mitochondrial enzyme involved in branched-chain amino acid and fatty acid metabolism.

18 May 2023

Using synthetic peptides for inflammatory disease diagnosis

Scientists have developed a peptide that binds to the protein calprotectin, a marker of major inflammatory disorders, and shown that it is suitable for diagnostic tests.

17 May 2023

Ticks found to harbor and release prions of chronic wasting disease

Researchers determined whether ticks contain transmission-relevant amounts of chronic wasting disease.

17 May 2023

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

Researchers generated six human monoclonal antibodies that prevented infection.

17 May 2023

New process for automated and highly accurate reporting of NGS-based clonality testing

A new research paper was published in Oncotarget's Volume 14 on May 12, 2023, entitled, "Development and implementation of an automated and highly accurate reporting process for NGS-based clonality testing."

16 May 2023

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Announcing a new article publication for BIO Integration journal. Antibody-drug conjugates (ADCs) have the following advantages: target specificity; wide therapeutic index; and prolonged circulation half-life.

15 May 2023

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Researchers discuss the use of endo-lysosome-targeted nanoparticles for delivering antiviral therapy to treat coronavirus infections.

15 May 2023

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Finding, cultivating, and bioengineering organisms that can digest plastic not only aids in the removal of pollution, but is now also big business.

13 May 2023

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

Researchers conducted a phase I clinical trial of a personalized mRNA neoantigen vaccine.

12 May 2023

COVID-19 that occurs after vaccination carries a much lower risk of severe illness

COVID-19 vaccination associated with lower rates of ICU admission and in-hospital mortality during the dominance of the Delta and Omicron variants.

11 May 2023

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

When exposed to stressful conditions, several proteins tend to misfold and form aggregates inside or outside cells.

11 May 2023

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Research compares the durability of neutralizing antibody responses among recipients of three different COVID-19 vaccines (BNT162b2, mRNA-1273, and Ad26.COV2.S) over a period of 6 months.

11 May 2023

Ketogenic diet's surprising impact on opioid sensitivity and withdrawal

Research investigates the effects of a ketogenic diet (KD) on responses to oxycodone, a commonly prescribed opioid for pain management. The study found sex-biased effects of KD on oxycodone responses in mice, suggesting potential implications for clinical pain management and treatment of opioid use disorder.

10 May 2023

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

Researchers investigated a cohort of patients who developed myocarditis after SARS-CoV-2 mRNA vaccination.

10 May 2023

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Research paper reports the results of a phase 3 clinical trial evaluating the efficacy and safety of the FINLAY-FR-2 and FINLAY-FR-1A vaccines in Iranian adults.

7 May 2023

Cancer stem cell test can lead to increased survival for patients with glioblastoma

New multi-institutional phase 3 clinical trial data published May 2 in Cell Reports Medicine found that a cancer stem cell test can accurately decide more effective treatments and lead to increased survival for patients with glioblastoma, a deadly brain tumor.

5 May 2023

The Human Protein Atlas and Precision Medicine

In this interview, Mathias Uhlen, the Director of the Human Protein Atlas, talks to NewsMed about the Human Protein Atlas and Precision Medicine.

From MGI 4 May 2023

Is an increase in cortisol levels associated with impaired working-memory retrieval and recognition in students?

Researchers examined the memory scores and electroencephalogram profiles of students to understand exam-induced stress and anxiety among the student population.

4 May 2023

Gyros Protein Technologies introduces Gyrolab Generic Cyno ADA Kit Reagents to support pre-clinical immunogenicity assessment

Gyros Protein Technologies AB, a leading provider of peptide synthesizers and reagents and a pioneer in automated nanoliter-scale immunoassays, today announced the introduction of Gyrolab® Generic Cyno Anti-Drug Antibodies (ADA) Kit Reagents, for the detection of circulating immune complexes of human IgG with cyno anti-human IgG.

From Gyros Protein Technologies AB 4 May 2023

Wildlife in Britain found free of SARS-CoV-2, but novel virus discovered in stoats

Scientists in the United Kingdom have conducted a large-scale screening for sarbecoviruses and pan-coronaviruses in British Wildlife to investigate the occurrence of widespread spillover events. They have identified a novel minacovirus in stoats recently introduced to the Orkney Islands.

3 May 2023

Assay News and Research

Efficient assay system aids rapid genetic diagnosis of mitochondrial diseases

Using synthetic peptides for inflammatory disease diagnosis

Ticks found to harbor and release prions of chronic wasting disease

Novel antibodies target human receptors to neutralize SARS-CoV-2 variants and future sarbecoviruses

New process for automated and highly accurate reporting of NGS-based clonality testing

HER2-TPMC proves to be a reasonable alternative for HER2-positive cancer chemotherapeutics

Nanoparticles take aim at COVID-19 with lysosome-targeted delivery

Swiss researchers identify plastic-degrading microbial strains in the Alps and Arctic region

Could personalized neoantigen vaccines prevent the recurrence of pancreatic cancer and increase patient survival?

COVID-19 that occurs after vaccination carries a much lower risk of severe illness

Extracellular chaperones mediate the lysosomal degradation of misfolded proteins

Adenovirus and mRNA COVID vaccines differ in 6-month antibody durability

Ketogenic diet's surprising impact on opioid sensitivity and withdrawal

New study finds elevated inflammatory cytokines and lymphocytes linked to rare cases of myocarditis after COVID-19 vaccination

The safety and efficacy of FINLAY-FR-2/1A, a new protein-based COVID-19 vaccine

Cancer stem cell test can lead to increased survival for patients with glioblastoma

The Human Protein Atlas and Precision Medicine

Is an increase in cortisol levels associated with impaired working-memory retrieval and recognition in students?

Gyros Protein Technologies introduces Gyrolab Generic Cyno ADA Kit Reagents to support pre-clinical immunogenicity assessment

Wildlife in Britain found free of SARS-CoV-2, but novel virus discovered in stoats

eBook: Using iPSCs models for human disease research and drug discovery eBook

Leveraging the power of automation to boost research

Automating research - solutions and best practices

How can microdialysis benefit drug development

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