Neurodegeneration News and Research

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Neurodegeneration is the umbrella term for the progressive loss of structure or function of neurons, including death of neurons.

Research identifies key role of CXCL9 cytokine in age-related chronic inflammation

An inflammatory-aging clock called developed by Stanford University School of Medicine and the Buck Institute for Research on Aging can predict how strong your immune system will be in 10 years, when you'll become frail or whether you may develop cardiovascular diseases a few years down the road.

14 Jul 2021

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Researchers from IDIBELL and the University of Barcelona have described that neurons derived from Parkinson's patients show impairments in their transmission before neurodegeneration.

7 Jul 2021

Scientists discover pathway that sheds new light on brain damage-induced cell division

Most human cells are able to repair damage by dividing at wounds.

6 Jul 2021

Brain cells snap DNA strands in numerous locations to make memories

The urgency to remember a dangerous experience requires the brain to make a series of potentially dangerous moves: Neurons and other brain cells snap open their DNA in numerous locations--more than previously realized, according to a new study--to provide quick access to genetic instructions for the mechanisms of memory storage.

6 Jul 2021

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Indiana University School of Medicine researchers are developing a new, noninvasive brain stimulation technique to treat neurological disorders, including pain, traumatic brain injury (TBI), epilepsy, Parkinson's disease, Alzheimer's disease and more.

2 Jul 2021

Tell-tale signs of high stroke risk may appear a decade in advance

The tell-tale signs of a person’s susceptibility to a stroke may appear up to 10 years before the event, suggests research published online in the Journal of Neurology Neurosurgery & Psychiatry.

2 Jul 2021

LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s

The LSL60101 compound, a specific ligand of the I2-IR receptors in the brain, could shed light on the development of future strategies against Alzheimer's disease.

29 Jun 2021

Alternative model of Alzheimer's emphasizes different set of mechanisms that lead to neurodegeneration

In the context of recent debate over the FDA's approval of aducanumab, it's refreshing to learn about a model of Alzheimer's neurodegeneration that doesn't start with the pathogenic proteins amyloid or Tau.

29 Jun 2021

Differences in human and mouse brain cells have implications for research into neurological disorders

A UCLA-led study comparing brain cells known as astrocytes in humans and mice found that mouse astrocytes are more resilient to oxidative stress, a damaging imbalance that is a mechanism behind many neurological disorders.

25 Jun 2021

Research findings on the links between air pollution and neurodegeneration

There is growing awareness that air pollutants are playing a critical role in the development of neurodegenerative diseases.

22 Jun 2021

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

By the time people with Alzheimer's disease start exhibiting difficulty remembering and thinking, the disease has been developing in their brains for two decades or more, and their brain tissue already has sustained damage. As the disease progresses, the damage accumulates, and their symptoms worsen.

21 Jun 2021

Investigational Alzheimer's drug reduces molecular markers of the disease

An investigational Alzheimer's drug reduced molecular markers of disease and curbed neurodegeneration in the brain, without demonstrating evidence of cognitive benefit, in a phase 2/3 clinical trial led by researchers at Washington University School of Medicine in St. Louis through its Dominantly Inherited Alzheimer Network-Trials Unit (DIAN-TU).

21 Jun 2021

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

Will a reduction in tau protein in brain neurons protect against Parkinson's disease and Lewy body dementias?

21 Jun 2021

Chan Zuckerberg Initiative announces nearly $28 million for visual proteomics

Today, the Chan Zuckerberg Initiative (CZI) announced nearly $28 million in grants to support technology developments that will allow researchers to see the inner workings of cells at near-atomic resolution through next-generation electron microscopy.

18 Jun 2021

Study creates a new model of Alzheimer's disease progression

Alzheimer's disease is the most common form of dementia and is characterized by neurodegeneration in regions of the brain involved in memory and learning. Amyloid beta and tau are two toxic proteins that build up in disease and cause eventual neuronal death, but little is known about how other cells in the brain react during disease progression.

14 Jun 2021

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

Like amyloid plaque, the genetic variant APOE4 has long been associated with Alzheimer's disease, but still little is known about the role the gene plays in the disease process.

14 Jun 2021

UCSF launches new initiative to propel the development of living therapeutics

UC San Francisco is launching a new initiative to propel the development of living therapeutics - a category of treatments broadly defined as human and microbial living cells that are selected, modified, or engineered to treat or cure disease - and bring them quickly to patients.

14 Jun 2021

PhoreMost appoints Christian Dillon as Vice President of Biology

PhoreMost Ltd today announced it has appointed Dr Christian Dillon as Vice President of Biology.

From PhoreMost 14 Jun 2021

Naked mole rats may hold the key to new treatments for cancer, dementia

Scientists say naked mole rats - a rodent native to West Africa - may hold the key to new treatments for degenerative diseases such as cancer and dementia. The reclusive animals have a lifespan far in excess of other rodents - for example, mice and rats live about two years, whereas naked mole rats can live for 40 or 50 years.

11 Jun 2021

New approach could revolutionize treatment, prevention of Parkinson’s disease

Researchers from Brain Research Institute, Niigata University, Japan may have unraveled a new approach that could revolutionize the treatment, prevention, and possibly reversal of the damages that could lead to Parkinson's Disease (PD).

11 Jun 2021

Neurodegeneration News and Research

Further Reading

Research identifies key role of CXCL9 cytokine in age-related chronic inflammation

Researchers identify early functional deficiencies in neurons derived from Parkinson's patients

Scientists discover pathway that sheds new light on brain damage-induced cell division

Brain cells snap DNA strands in numerous locations to make memories

IU researchers developing noninvasive brain stimulation technique to treat neurological disorders

Tell-tale signs of high stroke risk may appear a decade in advance

LSL60101 compound improves cognitive deficit in murine models with Alzheimer’s

Alternative model of Alzheimer's emphasizes different set of mechanisms that lead to neurodegeneration

Differences in human and mouse brain cells have implications for research into neurological disorders

Research findings on the links between air pollution and neurodegeneration

High levels of protein linked with heart health could protect against Alzheimer's-like brain damage

Investigational Alzheimer's drug reduces molecular markers of the disease

Role of tau in pathogenesis of Lewy body dementias is distinct from Alzheimer’s disease, suggests study

Chan Zuckerberg Initiative announces nearly $28 million for visual proteomics

Study creates a new model of Alzheimer's disease progression

USC study suggests new treatment target for Alzheimer's disease in people with APOE4 gene

UCSF launches new initiative to propel the development of living therapeutics

PhoreMost appoints Christian Dillon as Vice President of Biology

Naked mole rats may hold the key to new treatments for cancer, dementia

New approach could revolutionize treatment, prevention of Parkinson’s disease

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