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Curve along edge of tumor may play major role in cancer cell metastasis

Only a few cells in a cancerous tumor are able to break away and spread to other parts of the body, but the curve along the edge of the tumor may play a large role in activating these tumor-seeding cells, according to a new University of Illinois study.

29 Apr 2016

New miniaturized microscope offers unprecedented insight into nervous system function

A microscope about the size of a penny is giving scientists a new window into the everyday activity of cells within the spinal cord. The innovative technology revealed that astrocytes--cells in the nervous system that do not conduct electrical signals and were traditionally viewed as merely supportive--unexpectedly react to intense sensation.

28 Apr 2016

Bacterial invasion of lungs can lead to inflammation in COPD

Chronic obstructive pulmonary disease (COPD) is a common smoking-related lung illness and the third leading cause of death in the United States. Scientists have long believed that inhaling toxic gases and particles from tobacco smoke causes inflammation of the small airways in the lungs, leading to the development of COPD. However, the theory doesn't explain why airway inflammation and disease progression continue even after the patient stops smoking.

28 Apr 2016

Maternal exposure to air pollution increases risk of long-term health problems in children

Even small amounts of air pollution appear to raise the risk of a condition in pregnant women linked to premature births and lifelong neurological and respiratory disorders in their children, new Johns Hopkins Bloomberg School of Public Health research suggests.

28 Apr 2016

Yoga exercise may reduce impact of asthma on people's quality of life

A new Cochrane Review, published in the Cochrane Library today, suggests that yoga may have a beneficial effect on symptoms and quality of life in people with asthma, but effects on lung function and medication use are uncertain.

27 Apr 2016

TGen scientists trace likely origins, dispersal of fungus that causes Valley Fever

Using the latest in genomic analysis technologies, scientists at the Translational Genomics Research Institute have tracked the likely origins and dispersal of the fungus that causes Valley Fever, according to a study published today in the journal mBio, the premiere journal for reporting high impact microbiological research.

27 Apr 2016

Newly published manuscripts enhance understanding of the immune system

MedImmune, the global biologics research and development arm of AstraZeneca, today announced that it has achieved a significant scientific milestone by publishing three manuscripts in Nature Immunology that advance the understanding of the immune system and highlight underlying mechanisms in two little-understood disease areas -- chronic obstructive pulmonary disease (COPD) and systemic lupus erythematosus (SLE).

26 Apr 2016

Salk scientists reveal how cellular fuel gauge plays unexpected role in development

Salk scientists have revealed how a cellular "fuel gauge" responsible for monitoring and managing cells' energy processes also has an unexpected role in development. This critical link could help researchers better understand cancer and diabetes pathways.

26 Apr 2016

Five simple steps could reduce future life-threatening asthma attacks and hospital admissions

A national care check list (or ‘care bundle’) is launched today for NHS hospitals discharging asthma patients who have recently received treatment for an acute asthma attack.

26 Apr 2016

Children living closer to major roadways have increased risk of lower lung function, study finds

According to new research led by Beth Israel Deaconess Medical Center pulmonologist and critical care physician Mary B. Rice, MD, MPH, improved air quality in U.S. cities since the 1990s may not be enough to ensure normal lung function in children. The findings were recently published in the American Journal of Respiratory and Critical Care, a journal of the American Thoracic Society.

26 Apr 2016

Hydrocortisone drug can also prevent lung damage in premature babies

Research from Ann & Robert H. Lurie Children's Hospital of Chicago conducted in mice shows the drug hydrocortisone -- a steroid commonly used to treat a variety of inflammatory and allergic conditions -- can also prevent lung damage that often develops in premature babies treated with oxygen.

26 Apr 2016

Meta-analysis supports combination therapy for PAH patients

A meta-analysis shows that clinical worsening is significantly less likely in patients with pulmonary arterial hypertension if they are given combination treatment, rather than monotherapy.

25 Apr 2016

Scientists discover Hobit, Blimp1 genes that fight disease-causing pathogens

Melbourne researchers have uncovered the genes responsible for the way the body fights infection at the point of 'invasion' - whether it's the skin, liver, lungs or the gut.

25 Apr 2016

3-D imaging of fibroblastic foci may help researchers study disease progression in IPF patients

Idiopathic pulmonary fibrosis (IPF) is a fatal disease in which progressive scarring of the lungs leads to respiratory failure. Lung scarring in IPF takes the form of aggregates of proliferating fibroblasts and myofibroblasts, known as "fibroblastic foci", which deposit collagen and other fibrotic components. These foci are thought to form in response to lung injury.

22 Apr 2016

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Pediatric researchers have devised an innovative, safe and minimally invasive procedure that helps relieve rare but potentially life-threatening airway blockages occurring in children who had surgery for congenital heart defects.

22 Apr 2016

Macrophages play key role in quick tissue repair

While scientists have known for many years that there are cells living in the cavities surrounding various organs such as the heart, lung and liver, their function has remained unknown. A recent Cumming School of Medicine study examined these cells, and discovered they play an integral role in fast tissue repair. The study was published in the journal Cell this month.

22 Apr 2016

Blocking IL-1 signalling molecule could alleviate asthma symptoms

Scientists have made a discovery that could lead to improved treatment for asthma sufferers.They have found that blocking a certain signalling molecule can alleviate symptoms such as mucus production, swelling (edema), and constriction of the airways in the lungs.

21 Apr 2016

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

Cancer cells communicate with their environment through cell molecules that pass on signals to the inside of the cell. The signals help cancer cells multiply and migrate, spreading the disease.

21 Apr 2016

Motivational interviewing can help reduce risky use of pain pills

As America battles an epidemic of deaths from misused pain pills, a new study suggests an inexpensive way to cut risky use of these drugs by people who have a high chance of overdosing.

21 Apr 2016

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

Watercress extract taken multiple times a day significantly inhibits the activation of a tobacco-derived carcinogen in cigarette smokers, researchers at the University of Pittsburgh Cancer Institute, partner with UPMC Cancer Center, demonstrated in a phase II clinical trial presented today at the American Association for Cancer Research Annual Meeting in New Orleans.

21 Apr 2016

Lungs News and Research

Curve along edge of tumor may play major role in cancer cell metastasis

New miniaturized microscope offers unprecedented insight into nervous system function

Bacterial invasion of lungs can lead to inflammation in COPD

Maternal exposure to air pollution increases risk of long-term health problems in children

Yoga exercise may reduce impact of asthma on people's quality of life

TGen scientists trace likely origins, dispersal of fungus that causes Valley Fever

Newly published manuscripts enhance understanding of the immune system

Salk scientists reveal how cellular fuel gauge plays unexpected role in development

Five simple steps could reduce future life-threatening asthma attacks and hospital admissions

Children living closer to major roadways have increased risk of lower lung function, study finds

Hydrocortisone drug can also prevent lung damage in premature babies

Meta-analysis supports combination therapy for PAH patients

Scientists discover Hobit, Blimp1 genes that fight disease-causing pathogens

3-D imaging of fibroblastic foci may help researchers study disease progression in IPF patients

Pediatric researchers develop minimally invasive techniques to treat plastic bronchitis

Macrophages play key role in quick tissue repair

Blocking IL-1 signalling molecule could alleviate asthma symptoms

SI-2 molecule can inhibit tumor growth in breast cancer mouse model

Motivational interviewing can help reduce risky use of pain pills

Clinical study shows watercress extract inhibits carcinogen activation in cigarette smokers

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