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Scientists determine structure of endomannosidase enzyme

Scientists have determined the structure of the enzyme endomannosidase, significantly advancing our understanding of how a group of devastating human viruses including HIV and Hepatitis C hijack human enzymes to reproduce and cause disease.

4 Jan 2012

Working in Kazakhstan to end HIV stigma, discrimination

In this post on USAID's "IMPACTblog," Erin McKee, USAID mission director for the Central Asian Republics, recounts a discussion roundtable with people "on the front lines" in the battle against HIV/AIDS in Kazakhstan.

4 Jan 2012

PlusNews highlights 10 major HIV headlines of 2011

In a year-end recap of 10 major HIV-related headlines, PlusNews writes, "It's been a roller coaster of a year in HIV and AIDS. AIDS turned 30 in 2011, and with new evidence of the effectiveness of HIV treatment as prevention, experts are increasingly talking about 'the end of AIDS.'

4 Jan 2012

State Department fact sheets examine cholera, food security, health progress in Haiti

The State Department has released a series of fact sheets examining the U.S. government's two-year progress in Haiti. One fact sheet examines government efforts to "lessen the severity of the cholera outbreak" in Haiti.

4 Jan 2012

J&J will not join Medicines Patent Pool; Company's pharma head says mechanism could 'cause disaster'

Pharmaceutical company "Johnson & Johnson has rejected calls to offer patent rights on its HIV medicines to generic drug companies through a" Medicines Patent Pool, created to promote low-cost antiretroviral drugs in low-income countries and the development of new drug combinations and formulations, the Financial Times reports.

4 Jan 2012

Woman's ovarian cycle plays an important role in her susceptibility to infection

A new research report in the Journal of Leukocyte Biology suggests that a woman's ovarian cycle plays an important role in her susceptibility to infection.

4 Jan 2012

Similar sounding drug names should come with warnings

There have been mix ups and medication errors with similar sounding names of drugs - eye drops called Durezol and salicylic acid-containing wart remedy Duresal for example.

1 Jan 2012

Drinking untreated water increases risk of mycobacterial infection

Infections caused by mycobacteria (bacteria which are the cause of diseases such as tuberculosis in humans and animals) have a great impact on public health, animal health and the health of ecosystems in rural areas of Uganda.

29 Dec 2011

Bali tattoo and HIV transmission scare

Tourists who have gotten themselves tattooed or pierced whilst in Bali are being warned to seek medical advice after a Western Australian man reportedly contracted HIV during a recent holiday trip.

28 Dec 2011

Critical considerations for adenovirus-based HIV vaccine trials

A clinical trial testing a candidate HIV vaccine known as the STEP study was halted in September 2007 after interim analysis indicated that the vaccine did not work. Moreover, subsequent analyses indicated that the vaccine made some individuals more susceptible to HIV, in particular individuals who had pre-existing immune effectors (antibodies) that recognized a component of the vaccine (adenovirus serotype 5 [Ad5]).

28 Dec 2011

Pioneer in infectious disease medicine shares his perspectives in new podcast series

Beginning this month, the journal Medicine launches a series of podcasts featuring pioneering infectious disease physician John Bartlett, MD. Medicine is published by Lippincott Williams & Wilkins, a part of Wolters Kluwer Health.

28 Dec 2011

FDA accepts Gilead's Quad HIV regimen NDA for review

Gilead Sciences, Inc. announced today that the U.S. Food and Drug Administration (FDA) has accepted for review the New Drug Application (NDA) for the Quad, a complete single-tablet HIV regimen containing elvitegravir, cobicistat, emtricitabine and tenofovir disoproxil fumarate.

26 Dec 2011

Roundup: HIV staff to be cut in Ga.; Abortion news in N.J., Mo.; Wis. Medicaid coverage in limbo

A loss of $3.7 million in federal funds is forcing Georgia to reduce its workforce for HIV prevention. After an inquiry by Georgia Health News, the Department of Public Health this week acknowledged that 20 people in state health districts have been notified they will probably lose their jobs in January, and that an unspecified number of staffers at the department level have received the same notification.

23 Dec 2011

Science names HIV prevention trial as '2011 Breakthrough of the Year'

"The journal Science has chosen the HPTN 052 clinical trial, an international HIV prevention trial sponsored by the National Institute of Allergy and Infectious Diseases (NIAID)," which found that early treatment with antiretroviral drugs (ARVs) reduced the risk of transmission among sero-discordant partners by 96 percent, as the "2011 Breakthrough of the Year," an NIH press release states (12/22).

23 Dec 2011

ARV drugs can prevent transmission of HIV

The finding of a team of researchers - including several members from Johns Hopkins - that HIV treatment with antiretroviral drugs (ARVs) can actually prevent transmission of the virus from an infected person to his or her uninfected partner has been named "Breakthrough of the Year" for 2011 by the journal Science.

23 Dec 2011